| Movie | 1999 | Uninvited Guest | Mecca | |
| Movie | 2021 | Adventures In Christmasing | Parker Baldwin | |
| Movie | 2021 | Live in Front of a Studio Audience: The Facts of Life and Diff'rent Strokes | Self | |
| Movie | 1988 | Dare to Say No! | Self | |
| Movie | 2011 | Monster Mutt | | |
| Movie | 2012 | What to Expect When You're Expecting | Social Worker | |
| Movie | 2012 | Be Inspired: The Life of Heavy D | Self | |
| Movie | 2001 | The Facts of Life Reunion | Dorothy 'Tootie' Ramsey | |
| Movie | 2014 | For Better or For Worse | Roseanne | |
| Movie | 2002 | NBC 75th Anniversary Special | Self | |
| Movie | 1980 | The Comeback Kid | Molly | |
| Movie | 1983 | The 1st Annual NBC Yummy Awards | | |
| Movie | 1982 | The Facts of Life Goes to Paris | Tootie Ramsey | |
| Movie | 1987 | The Facts of Life Down Under | Tootie Ramsy | |
| Movie | 2024 | The Gutter | Vicki | |
| Movie | 2000 | Hidden Blessings | Carrie McNichols | |
| Movie | 1987 | Walt Disney World Celebrity Circus | Self | |
| Movie | 2012 | A Cross to Bear | Joan | |
| Movie | 2017 | A Question of Faith | Theresa Newman | |
| Movie | 1980 | Children of Divorce | Denise Williams | |
| Movie | 2017 | Wrapped Up In Christmas | Courtney Widmore | |
| Movie | 2018 | Merry Wishmas | Celine | |
| Movie | 2021 | Me & Mrs. Jones | Desiree | |
| Movie | 2019 | You Light Up My Christmas | Emma Simmons | |
| Movie | 1982 | The Kid with the Broken Halo | Teri Desautel | |
| Movie | 2000 | Glow | Miss Downer | |
| Movie | 1986 | Disneyland's Summer Vacation Party | Self | |
| Movie | 1977 | Have I Got a Christmas for You | Sharon Hayes | |
| Movie | 1985 | Disneyland's 30th Anniversary Celebration | Self | |
| Movie | 1981 | Good Evening Captain | Self | |
| Movie | 1988 | It's OK to Say No to Drugs | Self | |
| Movie | 1984 | The Stars Salute the U.S. Olympic Team | | |
| Movie | 2006 | My Nappy Roots: A Journey Through Black Hair-itage | Self | |
| Movie | 2021 | The Upshaws - The Afterparty | Self | |
| TV Show | 1974 | Good Times | | 2 |
| TV Show | 1992 | Martin | | 1 |
| TV Show | 2001 | One on One | Ms. Swain | 2 |
| TV Show | 2001 | The Division | Principal Ogden | 2 |
| TV Show | 1979 | The Facts of Life | Tootie Ramsey | 201 |
| TV Show | 1996 | Kenan & Kel | Miss Horn | 2 |
| TV Show | 2003 | Miss Match | Sherri | 1 |
| TV Show | 1990 | The Fresh Prince of Bel-Air | Monique | 2 |
| TV Show | 1978 | Diff'rent Strokes | Dorothy 'Tootie' Ramsey | 6 |
| TV Show | 2003 | Eve | Rochelle | 1 |
| TV Show | 2005 | The Comeback | | 1 |
| TV Show | 1996 | E! True Hollywood Story | | 1 |
| TV Show | 2019 | Tamron Hall | Self - Guest | 3 |
| TV Show | 1978 | Mork & Mindy | | 1 |
| TV Show | 1996 | The Steve Harvey Show | | 1 |
| TV Show | 1993 | Living Single | Regine Hunter | 118 |
| TV Show | 1978 | Baby, I'm Back | | 13 |
| TV Show | 1996 | C Bear and Jamal | Maya (voice) | 16 |
| TV Show | 2021 | The Upshaws | Regina | 48 |
| TV Show | 2000 | Strong Medicine | Lottie | 1 |
| TV Show | 1951 | Hallmark Hall of Fame | Sharon Hayes | 1 |
| TV Show | 2008 | The Cleaner | | 1 |
| TV Show | 1976 | Battle of the Network Stars | | 2 |
| TV Show | 1997 | The View | Self - Guest | 1 |
| TV Show | 2008 | Summer Showdown | | 12 |
| TV Show | 1998 | Hollywood Squares | Self - Panelist | 5 |
| TV Show | 1993 | Intimate Portrait | Self | 2 |
| TV Show | 2005 | Dancing with the Stars | Self - Contestant | 7 |
| TV Show | 2017 | Living the Dream | Rhoda | 12 |
| TV Show | 2017 | Battle of the Network Stars | Self | 1 |
| TV Show | 1991 | Roc | Ruth | 1 |
| TV Show | 2022 | Sherri | Self - Guest | 1 |
| TV Show | 2021 | Celebrity Wheel of Fortune | Self - Contestant | 1 |
| TV Show | 2015 | Celebrity Family Feud | Self | 1 |
| TV Show | 2021 | Name That Tune | Self - Contestant | 1 |
| TV Show | 2009 | Watch What Happens Live with Andy Cohen | Self - Guest | 4 |
| TV Show | 2019 | The Very Very Best of the 70s | Self - Commentator | 1 |
| TV Show | 2001 | Good Day Live | Self | 1 |
| TV Show | 2011 | Impractical Jokers | | 1 |
| TV Show | 2008 | The Real Housewives of Atlanta | Self | 21 |
| TV Show | 2016 | To Tell the Truth | Self - Panelist | 1 |
| TV Show | 1992 | The Golden Palace | Trisha | 1 |
| TV Show | 1981 | Entertainment Tonight | Self | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 1 |
| TV Show | 1979 | Roots: The Next Generations | Lydia Haley | 7 |
| TV Show | 2016 | Insecure | Mabel | 1 |
| TV Show | 1995 | The Drew Carey Show | Kate's Double | 1 |
| TV Show | 2018 | Cobra Kai | Sandra Robinson | 1 |
