| Movie | 1969 | Butch Cassidy and the Sundance Kid | Agnes | |
| Movie | 1981 | History of the World: Part I | Madame Defarge | |
| Movie | 1974 | Young Frankenstein | Frau Blücher | |
| Movie | 1996 | Making Frankensense of Young Frankenstein | Frau Blücher (archive footage) | |
| Movie | 2004 | Spanglish | Evelyn Wright | |
| Movie | 1999 | The Iron Giant | Mrs. Lynley Tensedge (voice) | |
| Movie | 1974 | Daisy Miller | Mrs. Ezra Miller | |
| Movie | 1993 | The Beverly Hillbillies | Granny | |
| Movie | 2009 | Love Takes Wing | Hattie Clarence | |
| Movie | 1979 | Scavenger Hunt | Mildred Carruthers | |
| Movie | 2005 | Sky High | Nurse Spex | |
| Movie | 1989 | Prancer | Mrs. McFarland | |
| Movie | 1980 | Herbie Goes Bananas | Louise Trends | |
| Movie | 1971 | The Last Picture Show | Ruth Popper | |
| Movie | 1977 | High Anxiety | Nurse Charlotte Diesel | |
| Movie | 1995 | Now and Then | Grandma Albertson | |
| Movie | 2005 | The Longest Yard | Lynette | |
| Movie | 1999 | Music of the Heart | Assunta | |
| Movie | 2006 | Beerfest | Great Gam Gam | |
| Movie | 1973 | Dillinger | Anna Sage | |
| Movie | 1987 | Walk Like a Man | Margaret Shand | |
| Movie | 1994 | A Troll in Central Park | Queen Gnorga (voice) | |
| Movie | 2008 | The Women | Maggie | |
| Movie | 2013 | Mel Brooks: Make a Noise | Self (archive footage) | |
| Movie | 2002 | The Mary Tyler Moore Reunion | Self | |
| Movie | 1970 | Lovers and Other Strangers | Bernice Henderson | |
| Movie | 1977 | The Mouse and His Child | Euterpe (voice) | |
| Movie | 2000 | Gen¹³ | Helga (voice) | |
| Movie | 2009 | American Cowslip | Sandy | |
| Movie | 2010 | Expecting Mary | Annie | |
| Movie | 2010 | You Again | Helen (uncredited) | |
| Movie | 1974 | Death Sentence | Susan Davies | |
| Movie | 1979 | The North Avenue Irregulars | Claire | |
| Movie | 2003 | Alex & Emma | Grandmother | |
| Movie | 1981 | Perfectly Frank: Frank Loesser Revued | Performer | |
| Movie | 1955 | Kiss Me Deadly | Christina Bailey | |
| Movie | 1970 | WUSA | Philomene | |
| Movie | 2013 | The Croods | Gran (voice) | |
| Movie | 1982 | Miss All-American Beauty | Agatha Blaine | |
| Movie | 1977 | Yabba Dabba Doo! The Happy World of Hanna-Barbera | Self | |
| Movie | 1991 | Picture This: The Times of Peter Bogdanovich in Archer City, Texas | Self | |
| Movie | 1990 | Texasville | Ruth Popper | |
| Movie | 1956 | The Rack | Caroline | |
| Movie | 2005 | The Californians | Eileen Boatwright | |
| Movie | 1988 | Hansel and Gretel | Griselda the Witch | |
| Movie | 1995 | Between Love and Honor | Anna Collura | |
| Movie | 1993 | Double, Double, Toil and Trouble | Aunt Agatha / Aunt Sofia | |
| Movie | 1983 | The Demon Murder Case | Joan Greenway | |
| Movie | 2002 | Manna from Heaven | Helen | |
| Movie | 1973 | Dying Room Only | Jean Mitchell | |
| Movie | 1980 | S.O.S. Titanic | Molly Brown | |
| Movie | 2012 | Gambit | Grandma Merle | |
| Movie | 2011 | The Fields | Gladys | |
| Movie | 1975 | Crazy Mama | Melba | |
| Movie | 1973 | Charley and the Angel | Nettie Appleby | |
| Movie | 1984 | Ernie Kovacs: Between the Laughter | Mary Kovacs | |
| Movie | 1970 | The People Next Door | Tina Hoffman | |
| Movie | 1980 | Foolin' Around | Samantha | |
| Movie | 2012 | The Oogieloves in the Big Balloon Adventure | Dotty Rounder | |
| Movie | 1973 | Happy Mother's Day, Love George | Ronda | |
| Movie | 1972 | Haunts of the Very Rich | Ellen Blunt | |
| Movie | 1977 | It Happened One Christmas | Clara Oddbody | |
| Movie | 2005 | Buzz | | |
| Movie | 1991 | In Broad Daylight | Ruth Westerman | |
| Movie | 1962 | The Chapman Report | Miss Selby | |
| Movie | 1990 | The Giant of Thunder Mountain | Narrator / The Elder Amy | |
| Movie | 1975 | Someone I Touched | Laura Hyatt | |
| Movie | 1974 | Thursday's Game | Lois Ellison | |
| Movie | 2001 | The Amati Girls | Dolly Amati | |
| Movie | 1990 | Love Hurts | Ruth Weaver | |
| Movie | 2015 | The Wedding Ringer | Grandma Palmer | |
| Movie | 1971 | Suddenly Single | Joanne Hackett | |
| Movie | 1973 | A Brand New Life | Victoria Douglas | |
| Movie | 1993 | Without a Kiss Goodbye | Mrs. Samuels | |
| Movie | 1981 | The Acorn People | Nurse Betty Nelson | |
| Movie | 2019 | Being and Nothingness | Ivy | |
| Movie | 1974 | The Migrants | Viola Barlow | |
| Movie | 1986 | My Little Pony: The Movie | Hydia (voice) | |
| Movie | 2007 | Lake Placid 2 | Sadie | |
| Movie | 1969 | Silent Night, Lonely Night | Ginny | |
| Movie | 1997 | Annabelle's Wish | Aunt Agnes (voice) | |
| Movie | 2014 | Phineas and Ferb: Night of the Living Pharmacists | Mrs. Feyersied (voice) | |
| Movie | 1990 | Fine Things | Ruth Fine | |
| Movie | 2015 | Scouts Guide to the Zombie Apocalypse | Miss Fielder | |
| Movie | 2008 | New York, I Love You | Mitzie | |
| Movie | 1979 | The Muppet Movie | Lord's Secretary | |
| Movie | 2012 | Foodfight! | Brand X Lunch Lady (voice) | |
| Movie | 1988 | Going to the Chapel | Mrs. Haldane | |
| Movie | 2008 | Comedy Central Roast of Bob Saget | Self | |
| Movie | 1987 | The Facts of Life Down Under | Beverly Ann Stickle | |
| Movie | 1993 | Fade to Black | Ruth | |
| Movie | N/A | Everbrook (The Home) | | |
| Movie | 2016 | So B. It | Alice Wilinsky | |
| Movie | 2015 | Unity | Narrator (voice) | |
| Movie | 1991 | A Little Piece of Heaven | Edwina 'Ed' McKevin | |
| Movie | 1981 | Advice to the Lovelorn | Maggie Dale | |
| Movie | 2015 | This Is Happening | Estelle (Grandmother) | |
| Movie | 1980 | The Oldest Living Graduate | Maureen | |
| Movie | 2000 | Hanging Up | Pat Mozell | |
| Movie | 1995 | Nobody's Girls: Five Women of the West | Laura Evans | |
| Movie | 2015 | Baby, Baby, Baby | Actress | |
| Movie | 1987 | Sparky's Magic Piano | | |
| Movie | 1983 | Dixie: Changing Habits | Sister Eugenio | |
| Movie | 2014 | Adult World | Mary Ann | |
| Movie | 1999 | The Last Picture Show: A Look Back | Self | |
| Movie | 2016 | Is That a Gun in Your Pocket? | Maxine | |
| Movie | 1975 | A Girl Named Sooner | Old Mam Hawes | |
| Movie | 1985 | Deadly Intentions | Charlotte Raynor | |
| Movie | 2016 | The Bronx Bull | Lilian Forrester | |
| Movie | 2016 | The Comedian | May Conner | |
| Movie | 2015 | Mary Tyler Moore: A Celebration | Self / Phyllis Lindstrom (archive footage) | |
| Movie | 1996 | Beavis and Butt-Head Do America | Old Woman On Plane And Bus (voice) | |
| Movie | 1979 | Mrs. R's Daughter | Ruth Rendell | |
| Movie | 1987 | The Little Troll Prince | | |
| Movie | 1978 | Long Journey Back | Laura Casella | |
| Movie | 2006 | Scary Movie 4 | Mrs. Norris | |
| Movie | 2018 | I Can Only Imagine | Memaw | |
| Movie | 1991 | Mary Tyler Moore: The 20th Anniversary Show | Herself | |
| Movie | 1986 | Shadow Play | Millie Crown | |
| Movie | 2006 | Mrs. Harris | Pearl "Billie" Schwartz | |
| Movie | 1981 | Yesterday | Mrs Kramer | |
| Movie | 2020 | The Croods: A New Age | Gran (voice) | |
| Movie | 2020 | When We Last Spoke | Itasca | |
| Movie | 2018 | Lez Bomb | Josephine | |
| Movie | 1974 | Hitchhike! | Claire Stevens | |
| Movie | 1979 | Willa | Darla Jean | |
| Movie | 1971 | The Steagle | Rita Weiss | |
| Movie | 1973 | Crime Club | Hilary Kelton | |
| Movie | 1996 | Never Too Late | Olive | |
| Movie | 2009 | Hitchcock and Mel: Spoofing the Master of Suspense | Self | |
| Movie | 1993 | Spies | Pamela Beale | |
| Movie | 1984 | Donald Duck's 50th Birthday | Self | |
| Movie | 1983 | The Woman Who Willed a Miracle | May Lemke | |
| Movie | 1975 | Death Scream | Mrs. Singleton | |
| Movie | 1985 | Love Is Never Silent | Mrs. Anglin | |
| Movie | 2018 | It's Who You Know | Liz | |
| Movie | 1993 | My Boyfriend's Back | Maggie The Zombie Expert | |
| Movie | 2021 | High Holiday | Nana | |
| Movie | 2022 | Jump, Darling | Margaret | |
| Movie | 2015 | Enzian: When the Lights Go Up | Self (archive footage) | |
| Movie | 1993 | Miracle Child | Doc Betty | |
| Movie | 1976 | Telly... Who Loves Ya, Baby? | Self | |
| Movie | 2021 | Dear Diary: World's First Pranks | Gran (voice) | |
| Movie | 2021 | Not to Forget | Donna | |
| Movie | 2016 | A Wig and a Prayer: The Peaches Christ Story | Self | |
| Movie | 1972 | Of Thee I Sing | Mary Turner | |
| Movie | 2001 | The Animal | Cat Lady (uncredited) | |
| Movie | 1999 | The Titanic Chronicles | (voice) | |
| Movie | 1976 | The Love Boat | Iris Havlicek | |
| Movie | 1952 | Forgotten Children | Martha Berry | |
| Movie | 2011 | Obsession: Letters to David Lynch | Self | |
| Movie | 2003 | Bad Santa | Granny | |
| Movie | 1998 | Skip Chasers | | |
| Movie | 2017 | The Gliksmans | Helen Neuman | |
| TV Show | 1989 | The Simpsons | Mrs. Glick (voice) | 1 |
| TV Show | 1958 | 77 Sunset Strip | | 1 |
| TV Show | 1961 | Cain's Hundred | Katie Cortner | 1 |
| TV Show | 1999 | Family Guy | Cloris Leachman (voice) | 1 |
| TV Show | 1974 | Rhoda | | 2 |
| TV Show | 1975 | Phyllis | Phyllis Lindstrom | 48 |
| TV Show | 2005 | Beach Girls | Aunt Aida | 6 |
| TV Show | 1979 | The Facts of Life | Beverly Ann Stickle | 48 |
| TV Show | 1994 | Touched by an Angel | Ruth | 4 |
| TV Show | 1966 | That Girl | | 1 |
| TV Show | 1993 | The Nanny | Clara Mueller | 1 |
| TV Show | 2000 | Malcolm in the Middle | | 0 |
| TV Show | 2003 | Two and a Half Men | Norma | 1 |
| TV Show | 1969 | Marcus Welby, M.D. | Jean Cullen | 1 |
| TV Show | 2001 | The Ellen Show | Dot Richmond | 18 |
| TV Show | 1999 | Thanks | Grammy Winthrop | 6 |
| TV Show | 1955 | Gunsmoke | Flory Tibbs | 1 |
| TV Show | 1948 | Studio One | Mrs. Adams | 1 |
| TV Show | 1953 | General Electric Theater | Leah Beth | 1 |
| TV Show | 1962 | Saints and Sinners | Helen Graham | 1 |
| TV Show | 1959 | Hawaiian Eye | | 1 |
| TV Show | 1968 | Adam-12 | Judy | 1 |
| TV Show | 1951 | Hallmark Hall of Fame | Martha Berry | 1 |
| TV Show | 1959 | Johnny Staccato | | 1 |
| TV Show | 1976 | The Muppet Show | Self - Special Guest Star | 1 |
| TV Show | 1959 | The Twilight Zone | Mrs. Fremont | 1 |
| TV Show | 2007 | The Wedding Bells | Edith Fleischman | 1 |
| TV Show | 1955 | Alfred Hitchcock Presents | Susan Stanger | 1 |
| TV Show | 1995 | Maybe This Time | Beasy | 1 |
| TV Show | 1962 | Going My Way | | 1 |
| TV Show | 1960 | Outlaws | | 2 |
| TV Show | 1961 | Target: The Corruptors! | | 1 |
| TV Show | 1999 | Twice in a Lifetime | | 1 |
| TV Show | 1965 | Run for Your Life | Deborah Wilson | 1 |
| TV Show | 1962 | The Virginian | Clara | 1 |
| TV Show | 1968 | Lancer | Angel Day | 2 |
| TV Show | 1960 | Thriller | Beatrice Stafford | 1 |
| TV Show | 1950 | Lux Video Theatre | Dottie | 1 |
| TV Show | 1954 | Climax! | Mrs. Sullivan | 1 |
| TV Show | 1959 | One Step Beyond | Rita Wallace | 1 |
| TV Show | 1967 | Judd for the Defense | | 1 |
| TV Show | 1958 | The Donna Reed Show | | 1 |
| TV Show | 1955 | Matinee Theater | | 1 |
| TV Show | 1948 | The Philco Television Playhouse | Jenny Blanchard | 1 |
| TV Show | 1972 | The Sixth Sense | | 1 |
| TV Show | 1958 | Wanted: Dead or Alive | Ann Barchester | 1 |
| TV Show | 1959 | Laramie | | 1 |
| TV Show | 1967 | The Guns of Will Sonnett | | 1 |
| TV Show | 1963 | Mr. Novak | Dorothy Hummer | 2 |
| TV Show | 1961 | The New Breed | Elsie Condon | 1 |
| TV Show | 1949 | Suspense | | 4 |
| TV Show | 1956 | Dick Powell's Zane Grey Theatre | Martha Jessop | 1 |
| TV Show | 1989 | The Nutt House | | 1 |
| TV Show | 1989 | The Nutt House | Mrs. Frick | 6 |
| TV Show | 1951 | Tales of Tomorrow | | 1 |
| TV Show | 1962 | Stoney Burke | | 1 |
| TV Show | 1961 | Dr. Kildare | Rhoda Kirsh | 4 |
| TV Show | 1956 | Telephone Time | | 1 |
| TV Show | 1994 | Storybook Cinema | | 9 |
| TV Show | 1961 | The Defenders | Angela Simms | 1 |
| TV Show | 1954 | Lassie | Ruth Martin | 2 |
| TV Show | 1991 | Walter & Emily | Emily Collins | 13 |
| TV Show | 1953 | Letter to Loretta | Ella | 1 |
| TV Show | 1975 | Cher | Self | 1 |
| TV Show | 2010 | Raising Hope | Maw Maw | 86 |
| TV Show | 2002 | The Twilight Zone | Agnes Fremont | 1 |
| TV Show | 1970 | The Mary Tyler Moore Show | Phyllis Lindstrom | 45 |
| TV Show | 2010 | Hawaii Five-0 | Ruth Tennenbaum | 1 |
| TV Show | 1993 | Diagnosis: Murder | Sudie | 1 |
| TV Show | 1970 | Night Gallery | Mrs. Fulton | 1 |
| TV Show | 1993 | Intimate Portrait | Self | 1 |
| TV Show | 1961 | The Mike Douglas Show | Self - Co-Host | 1 |
| TV Show | 1974 | Dinah! | Self | 2 |
| TV Show | 2010 | Top Gear | | 1 |
| TV Show | 1958 | 77 Sunset Strip | Eve Winters | 1 |
| TV Show | 1955 | Gunsmoke | Boni | 1 |
| TV Show | 1953 | Letter to Loretta | Ruth Harron | 1 |
| TV Show | 1953 | General Electric Theater | Miriam Raskin | 1 |
| TV Show | 1957 | Perry Mason | Gloria Shine | 1 |
| TV Show | 2005 | Dancing with the Stars | Self - Contestant | 13 |
| TV Show | 2017 | American Gods | Zorya Vechernyaya | 3 |
| TV Show | 1948 | The Ed Sullivan Show | Self | 2 |
| TV Show | 2011 | Bob's Burgers | Meryl (voice) | 1 |
| TV Show | 1962 | The Tonight Show Starring Johnny Carson | Self | 2 |
| TV Show | 1968 | The Name of the Game | Vera Walker | 1 |
| TV Show | 1996 | Promised Land | Aunt Ethel Mooster | 1 |
| TV Show | 2007 | Phineas and Ferb | Mrs. Feyersied (voice) | 1 |
| TV Show | 2007 | Phineas and Ferb | Doof's Mom (voice) | 1 |
| TV Show | 1955 | Alfred Hitchcock Presents | Mary Templeton | 1 |
| TV Show | 1951 | Hallmark Hall of Fame | Mrs. Anglin | 1 |
| TV Show | 1955 | Alfred Hitchcock Presents | Caroline Hardy | 1 |
| TV Show | 1948 | Studio One | | 1 |
| TV Show | 2011 | Franklin & Bash | Irina Lottye Kruskal | 1 |
| TV Show | 1961 | The Mike Douglas Show | Self | 2 |
| TV Show | 1990 | Ferris Bueller | Grandma | 1 |
| TV Show | 1954 | Climax! | Anne Colt | 1 |
| TV Show | 1958 | 77 Sunset Strip | Connie Wingate | 1 |
| TV Show | 1960 | Route 66 | Lydia Manning | 1 |
| TV Show | 2014 | Clarence | Cloris (voice) | 1 |
| TV Show | 2016 | To Tell the Truth | Self - Panelist | 1 |
| TV Show | 1949 | Suspense | Margaret Sou | 1 |
| TV Show | 1949 | Suspense | Ruth Shaw | 1 |
| TV Show | 1948 | The Philco Television Playhouse | Marianne Dashwood | 1 |
| TV Show | 1948 | The Philco Television Playhouse | | 1 |
| TV Show | 1948 | The Philco Television Playhouse | Patricia | 1 |
| TV Show | 1967 | Judd for the Defense | Louise Lockhart | 1 |
| TV Show | 1955 | Screen Director's Playhouse | Irma | 1 |
| TV Show | 2003 | Comedy Central Roasts | Self | 1 |
| TV Show | 1957 | Wagon Train | Loretta | 1 |
| TV Show | 1968 | The Dick Cavett Show | Self - Guest | 1 |
| TV Show | 2010 | Hot in Cleveland | Peg | 1 |
| TV Show | 1956 | Tony Awards | Self - Presenter | 2 |
| TV Show | 2014 | Girl Meets World | Mrs. Svorski | 1 |
| TV Show | 2009 | RuPaul's Drag Race | Self - Guest Judge | 1 |
| TV Show | 2013 | Kirstie | Shirley Kluszewski | 1 |
| TV Show | 1979 | Backstairs at the White House | Mrs. Jaffray | 4 |
| TV Show | 2019 | Mad About You | Mrs. Mandelbaum | 1 |
| TV Show | 2009 | Watch What Happens Live with Andy Cohen | Self - Guest | 1 |
| TV Show | 1953 | The Oscars | Self | 1 |
| TV Show | 1967 | Ironside | Molly Strong | 1 |
| TV Show | 2005 | The Office | Lily Hanaday | 1 |
| TV Show | 2000 | Malcolm in the Middle | Ida Welker | 11 |
| TV Show | 1944 | Golden Globe Awards | Self - Nominee | 1 |
| TV Show | 1944 | Golden Globe Awards | Self - Presenter | 1 |
| TV Show | 2003 | Happy Family | Lois, Peter's Mother | 1 |
| TV Show | 2017 | American Gods | Zorya Vechernyaya, the Evening Star | 8 |
| TV Show | 2016 | Justice League Action | Granny Goodness (voice) | 3 |
| TV Show | 1975 | Wonder Woman | Queen Hippolyta | 1 |
| TV Show | 2006 | The Megan Mullally Show | Self - Guest | 1 |
| TV Show | 2014 | Last Week Tonight with John Oliver | Self | 1 |
| TV Show | 1977 | The Love Boat | Karen Cooper | 1 |
| TV Show | 1967 | Mannix | Barker's Ex-Wife | 1 |
| TV Show | 1973 | The Bobby Darin Show | | 1 |
| TV Show | 1974 | Dinah! | | 1 |
| TV Show | 1962 | The Merv Griffin Show | Self | 2 |
| TV Show | 2013 | The Millers | Louise | 1 |
| TV Show | 2003 | Joan of Arcadia | Aunt Olive | 1 |
