| Movie | 2000 | Gladiator | Gracchus | |
| Movie | 2006 | Underworld: Evolution | Alexander Corvinus | |
| Movie | 2007 | The Golden Compass | Magisterial Emissary | |
| Movie | 1996 | Hamlet | King Claudius | |
| Movie | 1989 | Henry V | Chorus | |
| Movie | 1982 | Stranger in Town | The Stranger | |
| Movie | 1982 | Enigma | Kurt Limmer | |
| Movie | 1973 | The Day of the Jackal | Inspector Caron | |
| Movie | 2001 | Gosford Park | Probert | |
| Movie | 1998 | Love Is the Devil: Study for a Portrait of Francis Bacon | Francis Bacon | |
| Movie | 1998 | Animated Epics: Beowulf | Narrator ( voice ) | |
| Movie | 2004 | Strings | Nezo | |
| Movie | 1974 | The Odessa File | Klaus Wenzer | |
| Movie | 2005 | Nanny McPhee | Mr. Wheen | |
| Movie | 1982 | The Secret of NIMH | Nicodemus (voice) | |
| Movie | 2025 | Moss & Freud | Lucian Freud | |
| Movie | 1978 | The Medusa Touch | Townley - Publisher | |
| Movie | 1991 | Dead Again | Franklyn Madson | |
| Movie | 2002 | Revengers Tragedy | The Duke | |
| Movie | 2023 | Allelujah | Ambrose | |
| Movie | 2007 | The Old Curiosity Shop | Grandfather | |
| Movie | 2001 | The Body | Father Lavelle | |
| Movie | 2002 | The Gathering Storm | Stanley Baldwin | |
| Movie | 2000 | The Wyvern Mystery | Squire Fairfield | |
| Movie | 2005 | Bye Bye Blackbird | Lord Dempsey | |
| Movie | 2011 | Anonymous | Prologue | |
| Movie | 1993 | The Vision Thing | George Salisbury | |
| Movie | 1965 | Othello | Cassio | |
| Movie | 2011 | There Be Dragons | Honorio | |
| Movie | 2007 | The Riddle | The Tramp / Charles Dickens | |
| Movie | 1995 | Achilles | Narrator | |
| Movie | 2011 | Ironclad | Cornhill | |
| Movie | 1977 | Philby, Burgess and Maclean | Guy Burgess | |
| Movie | 1987 | Little Dorrit | Arthur Clennam | |
| Movie | 1979 | The Human Factor | Arthur Davis | |
| Movie | 2002 | Two Men Went To War | Maj. Merton | |
| Movie | 2008 | Adam Resurrected | Dr. Nathan Gross | |
| Movie | 2008 | A Bunch of Amateurs | Nigel Dewberry | |
| Movie | 2000 | Up at the Villa | Lucky Leadbetter | |
| Movie | 1987 | The Secret Garden | Archibald Craven | |
| Movie | 2002 | Ultimate Fights from the Movies | Gracchus (Gladiator) (archive footage) | |
| Movie | 1982 | The Hunchback of Notre Dame | Dom Claude Frollo | |
| Movie | 2024 | Gladiator II | Gracchus | |
| Movie | 1985 | Cyrano de Bergerac | Cyrano de Bergerac | |
| Movie | 2010 | Joe Maddison's War | Mr. Simpson | |
| Movie | 2007 | Anastezsi | Balzer | |
| Movie | 1996 | Breaking the Code | Alan Turing | |
| Movie | 1986 | On Wings of Fire | Self | |
| Movie | 2006 | Pinochet in Suburbia | Senator Augusto Pinochet | |
| Movie | 2003 | Broadway: The Golden Age, by the Legends Who Were There | Self | |
| Movie | 1988 | The Tenth Man | The Imposter | |
| Movie | 2012 | Last Will. & Testament | Himself | |
| Movie | 2014 | Effie Gray | Travers Twiss | |
| Movie | 2007 | Guantanamero | Guido | |
| Movie | N/A | Venom! Nine Ways to Die | Narrator | |
| Movie | 2022 | Peter O'Toole: Along the Sky Road to Aqaba | Self | |
| Movie | 1996 | Witness Against Hitler | General | |
| Movie | 2011 | Through the Weeping Glass: On the Consolations of Life Everlasting (Limbos & Afterbreezes in the Mütter Museum) | Narrator (voice) | |
| Movie | 2014 | Grace of Monaco | Count Fernando D'Aillieres | |
| Movie | 1994 | The Secret Garden | Archibald Craven (voice) | |
| Movie | 2013 | Muse of Fire | Self | |
| Movie | 2007 | Airlock, or How to Say Goodbye in Space | President | |
| Movie | 2009 | Diamonds | Piers Denmont | |
| Movie | 2023 | The Martini Shot | Errol | |
| Movie | 2010 | The King's Speech | Archbishop Cosmo Lang | |
| Movie | 1978 | Richard II | King Richard II | |
| Movie | 1990 | The Fool | Mr. Frederick / Sir John | |
| Movie | 1974 | Blue Blood | Gregory | |
| Movie | 1990 | Discovering Hamlet | Himself | |
| Movie | 1996 | Looking for Richard | Self - Interviewee | |
| Movie | 2002 | The Diaries of Vaslav Nijinsky | Nijinsky (voice) (as Sir Derek Jacobi) | |
| Movie | 2025 | Juliet & Romeo | The Friar | |
| Movie | 1986 | Mr. Pye | Mr. Pye | |
| Movie | 1970 | Three Sisters | Andrei | |
| Movie | 1980 | The Man Who Went Up in Smoke | Martin Beck | |
| Movie | 1967 | Much Ado About Nothing | Don John | |
| Movie | 2022 | Pearl Islands | Self | |
| Movie | 2015 | The Gospel of Luke | Narrator (voice) – King James Version | |
| Movie | 2000 | Wilfred | Voice | |
| Movie | 2002 | The Dinosaur Hunters | Narrator (voice) | |
| Movie | 2015 | Knights of Classic Drama at the BBC | Self (archive footage) | |
| Movie | 1962 | The Fishing Match | Eric | |
| Movie | 2021 | Rhythm of Life | Self | |
| Movie | 2001 | Revelation | Librarian | |
| Movie | 1980 | Hamlet | Hamlet | |
| Movie | 2000 | Victoria Wood with All the Trimmings | Various Characters | |
| Movie | 2009 | Endgame | Rudolph Agnew | |
| Movie | 2008 | Sidney Turtlebaum | Sidney Turtlebaum | |
| Movie | 1994 | Aladdin | The Magician (voice) | |
| Movie | 2012 | Jail Caesar | Sulla | |
| Movie | 2011 | National Theatre Live: King Lear | King Lear | |
| Movie | N/A | The Man Who Tried to Steal an Island | Narrator | |
| Movie | 2016 | Branagh Theatre Live: Romeo and Juliet | Mercutio | |
| Movie | 2016 | The History of Love | Leopold Gursky | |
| Movie | 2017 | Murder on the Orient Express | Edward Henry Masterman | |
| Movie | 2001 | Great Escape: The Untold Story | Narrator | |
| Movie | 2009 | Margot | Fred Ashton | |
| Movie | 2002 | Inquisition | Cardinal Grand Inquisitor | |
| Movie | 2013 | National Theatre Live: 50 Years on Stage | Claudius/Spooner | |
| Movie | 2010 | Hereafter | Derek Jacobi | |
| Movie | 2017 | Stratton | Ross | |
| Movie | 2008 | One of Those Days | Howard Whittam | |
| Movie | 2012 | The Halloween Kid | Narrator | |
| Movie | 2017 | A Christmas Carol Goes Wrong | Scrooge | |
| Movie | 1999 | The Chimes | Narrator | |
| Movie | 2006 | Mist: The Tale of a Sheepdog Puppy | Narrator | |
| Movie | 1986 | David Macaulay: Cathedral | Pierre (voice) | |
| Movie | 2019 | Tolkien | Professor Joseph Wright | |
| Movie | 2018 | Tomb Raider | Mr. Yaffe | |
| Movie | 1999 | Molokai: The Story of Father Damien | Father Leonor Fousnel | |
| Movie | 2018 | Nothing Is Truer than Truth | | |
| Movie | 2019 | Horrible Histories: The Movie — Rotten Romans | Claudius | |
| Movie | 1994 | David Macaulay: Roman City | Marcus Fabricius (voice) | |
| Movie | 2001 | David Macaulay: Mill Times | Priam Huntington (voice) | |
| Movie | 1989 | David Macaulay: Pyramid | Hordedef (voice) | |
| Movie | 2020 | Come Away | Mr. Brown | |
| Movie | 2009 | Morris: A Life with Bells On | Quentin Neely | |
| Movie | 2013 | Dangerous Edge: A Life of Graham Greene | Narrator (voice) | |
| Movie | 1981 | Charlotte | Daberlohn | |
| Movie | 1989 | The Congress | (voice) | |
| Movie | 2004 | Unforgivable Blackness: The Rise and Fall of Jack Johnson | Other Voices (voice) | |
| Movie | 2019 | The Warrior Queen of Jhansi | Lord Palmerston | |
| Movie | 1993 | Circle of Deceit | Randal | |
| Movie | 2007 | The Art of Francis Bacon | Derek Jacobi | |
| Movie | 2020 | The Host | Dr. Hobson | |
| Movie | 2019 | Muse | The Lawyer | |
| Movie | 1965 | Olivier Talks About Othello | (archive footage) | |
| Movie | 2002 | I, Claudius: A Television Epic | Self | |
| Movie | 1985 | The Statue of Liberty | Self (voice) | |
| Movie | 2022 | A Bird Flew In | David | |
| Movie | 2009 | Charles Dickens's England | Himself - Presenter | |
| Movie | 2021 | Say Your Prayers | Father Enoch | |
| Movie | N/A | Lead Heads | | |
| Movie | 2020 | Coronation Street: Queens of the Street | Himself | |
| Movie | 2002 | The Making of Gosford Park | Self | |
| Movie | 1998 | Basil | Father Frederick | |
| Movie | 2008 | Pompeii and the Roman Villa | Narrator | |
| Movie | 2017 | Celebration of the Tercentenary of the Founding of The Premier Grand Lodge | | |
| Movie | 2015 | Venom | Narrator | |
| Movie | 1978 | Mysterious Castles of Clay | Narrator | |
| Movie | 2011 | My Week with Marilyn | Sir Owen Morshead | |
| Movie | 2004 | Angelina Ballerina: The Show Must Go On | Mr. Operatski (voice) | |
| Movie | 2015 | Cinderella | King | |
| Movie | 2021 | Albert Speer und der Traum von Hollywood | Himself (archive footage) | |
| Movie | 2013 | You | Man | |
| Movie | 2020 | Breaking The Codes | | |
| Movie | 2025 | Tinsel Town | Albert | |
| Movie | 2008 | The Ties That Bind Us | The Master (archive footage) | |
| Movie | 2004 | Cloud Cuckoo Land | Victor | |
| Movie | 2005 | Strength and Honor: Production Pods | Self | |
| Movie | 2024 | Dame Maggie Smith - A Celebration | Self | |
| Movie | 1994 | One Corpse Too Many | Brother Cadfael | |
| Movie | 1994 | The Sanctuary Sparrow | Brother Cadfael | |
| Movie | 1994 | The Leper of St. Giles | Brother Cadfael | |
| Movie | 1994 | Monk's Hood | Brother Cadfael | |
| Movie | 1995 | The Virgin in the Ice | Brother Cadfael | |
| Movie | N/A | Frank and Percy | | |
| Movie | 2025 | Broken English | The Narrator | |
| Movie | 2016 | The Devil of Christmas | | |
| TV Show | 1971 | Budgie | Herbert Fletcher | 1 |
| TV Show | 2005 | Doctor Who Confidential | | 1 |
| TV Show | 1979 | Tales of the Unexpected | The Stranger | 2 |
| TV Show | 1993 | Frasier | Jackson Hedley | 1 |
| TV Show | 1979 | Minder | Freddie Fenton | 1 |
| TV Show | 2000 | Randall & Hopkirk (Deceased) | | 1 |
| TV Show | 2007 | In the Night Garden | Narrator (voice) | 100 |
| TV Show | 1976 | I, Claudius | Claudius | 12 |
| TV Show | 1951 | Hallmark Hall of Fame | Dom Claude | 1 |
| TV Show | 2021 | The Lost Pirate Kingdom | Narrator | 6 |
| TV Show | 1971 | The Rivals of Sherlock Holmes | William Drew | 1 |
| TV Show | 1974 | The Pallisers | | 26 |
| TV Show | 2014 | Inside No. 9 | Webster | 1 |
| TV Show | 1992 | The Velvet Claw | Narrator | 7 |
| TV Show | 2009 | Diamonds | | 2 |
| TV Show | 1994 | Cadfael | Brother Cadfael | 13 |
| TV Show | 2012 | Titanic: Blood and Steel | Lord Pirrie | 12 |
| TV Show | 2012 | Last Tango in Halifax | Alan | 24 |
| TV Show | 1974 | NOVA | Voice of Ernest Shackleton | 1 |
| TV Show | 2012 | Shakespeare Uncovered | Himself | 1 |
| TV Show | 2013 | Vicious | Stuart Bixby | 12 |
| TV Show | 2004 | Who Do You Think You Are? | Self | 1 |
| TV Show | 2004 | London | Tacitus | 3 |
| TV Show | 1956 | Tony Awards | Self - Nominee | 1 |
| TV Show | 2002 | The Jury | George Cording QC | 6 |
| TV Show | 2019 | Good Omens | The Metatron | 1 |
| TV Show | 2023 | The Following Events are Based on a Pack of Lies | Sir Ralph Unwin | 5 |
| TV Show | 2005 | Doctor Who | Professor Yana | 1 |
| TV Show | 2009 | Doctor Who Greatest Moments | Self | 1 |
| TV Show | 2011 | The Amazing World of Gumball | Narrator (voice) | 2 |
| TV Show | 1986 | Mr. Pye | Mr. Pye | 4 |
| TV Show | 2000 | Jason and the Argonauts | Phineas | 2 |
| TV Show | 2004 | The Long Firm | Lord Edward 'Teddy' Thursby | 4 |
| TV Show | 1990 | The Civil War | Various | 9 |
| TV Show | 1951 | Hallmark Hall of Fame | Archibald Craven | 1 |
| TV Show | 1951 | Hallmark Hall of Fame | Imposter | 1 |
| TV Show | 1994 | Baseball | Various (voice) | 0 |
| TV Show | 2023 | The American Buffalo | (voice) | 2 |
| TV Show | 2018 | Les Misérables | Bishop Myriel | 1 |
| TV Show | 2004 | Agatha Christie's Marple | Colonel Protheroe | 1 |
| TV Show | 2022 | The Sandman | Erasmus Fry | 1 |
| TV Show | 1996 | The West | Self (voice) | 1 |
| TV Show | 2019 | Good Omens | Metatron | 1 |
| TV Show | 2023 | U-Boat Wargamers | Narrator (voice) | 6 |
| TV Show | 2019 | Greatest Events of World War II in Colour | Narrator | 10 |
| TV Show | 1986 | Wedden, dat..? | Self | 1 |
| TV Show | 2016 | The Crown | Duke of Windsor | 1 |
| TV Show | 2024 | Ludwig | Mr. Todd | 1 |
| TV Show | 1992 | The World of Peter Rabbit and Friends | Mr. Jeremy Fisher (voice) | 1 |
| TV Show | 1956 | Tony Awards | Self - Winner | 1 |
| TV Show | 1994 | Baseball | (voice) | 1 |
| TV Show | 2003 | Henry VIII | Narrator | 2 |
| TV Show | 1991 | The Storyteller: Greek Myths | Daedalus | 1 |
| TV Show | 2003 | Doctor Who: Scream of the Shalka | The Master (voice) | 5 |
| TV Show | 1982 | Inside the Third Reich | Adolf Hitler | 2 |
