| Movie | 2019 | The Doctors: The Sylvester McCoy Years | | |
| Movie | 2013 | Doctor Who Live: The Afterparty | Self | |
| Movie | 2013 | Doctor Who Explained | Self | |
| Movie | 2019 | The Circuit | | |
| Movie | 2022 | The Munsters | Igor | |
| Movie | 1996 | Doctor Who | The Doctor | |
| Movie | 2008 | King Lear | The Fool | |
| Movie | 2012 | The Hobbit: An Unexpected Journey | Radagast the Brown | |
| Movie | 2000 | The Mumbo Jumbo | Mr. Tallman | |
| Movie | 2014 | Doctor Who: The Ultimate Time Lord with Peter Davison | Self | |
| Movie | 2020 | Conjuring: The Book of the Dead | Book Seller (archive footage) | |
| Movie | 2013 | The Hobbit: The Desolation of Smaug | Radagast the Brown | |
| Movie | 2023 | Necronomicon | Book Seller (archive footage) | |
| Movie | 2014 | The Hobbit: The Battle of the Five Armies | Radagast the Brown | |
| Movie | 1979 | The Secret Policeman's Ball | Various Roles | |
| Movie | N/A | Sylvester: Who's the Real McCoy? | Self | |
| Movie | 1993 | The Airzone Solution | Anthony Stanwick | |
| Movie | 2023 | Doctor on Display: Blackpool 2 | Self | |
| Movie | 1993 | Doctor Who: Dimensions in Time | The 7th Doctor | |
| Movie | 2013 | The Christmas Candle | Edward Haddington | |
| Movie | 2014 | The Seventeenth Kind | Rusty | |
| Movie | 2013 | The Five(ish) Doctors Reboot | Self | |
| Movie | 2023 | Talking Doctor Who | Self / The Doctor (7) (archive footage) | |
| Movie | 1991 | Doctor Who: The Hartnell Years | Self - Presenter | |
| Movie | 2023 | Sylvester McCoy Uncut | Himself | |
| Movie | 1994 | Myth Makers 28: Sylvester McCoy | Self | |
| Movie | 2001 | Then & Now | | |
| Movie | 2002 | My Doctor Who Diary | | |
| Movie | 2022 | The Munsters: Return to Mockingbird Lane | Igor / Self | |
| Movie | 2013 | Doctor Who: The Day of the Doctor | The Doctor (7) (archive footage) | |
| Movie | 2022 | Bug-Eyed Monsters Invade the Earth! | Klakk (voice) | |
| Movie | 2021 | Doctor Who: 24 Carat | The Doctor | |
| Movie | 2016 | Punk Strut: The Movie | DJ | |
| Movie | 2012 | The Inspector Chronicles | Uncle Roderick | |
| Movie | 1991 | The PanoptiCon Tapes Vol 1 - The Main Event | | |
| Movie | 1990 | The PanoptiCon Tapes II | | |
| Movie | 1990 | The PanoptiCon Tapes III | | |
| Movie | 1990 | The PanoptiCon Tapes IV | | |
| Movie | 1990 | The PanoptiCon Tapes V | | |
| Movie | 1986 | The PanoptiCon Tapes VI | | |
| Movie | 1996 | Spellbreaker: Secret of the Leprechauns | Flynn | |
| Movie | 1979 | Dracula | Walter | |
| Movie | 1994 | The Zero Imperative | Dr. Colin Dove | |
| Movie | 2018 | Hangover in Death Valley | General Zwick (archive footage) | |
| Movie | 2013 | Ian Levine: Downtime Redux | The Doctor | |
| Movie | 2021 | Christmas with Strangers | Self | |
| Movie | 1989 | Doctor Who: Battlefield | The Doctor | |
| Movie | 1989 | Doctor Who: The Curse of Fenric | The Doctor | |
| Movie | 2025 | Dead Before They Wake | Evan | |
| Movie | 2005 | Doctor Who: A New Dimension | Self | |
| Movie | 1979 | Big Jim and the Figaro Club | Turps | |
| Movie | 1989 | Doctor Who: Survival | The Doctor | |
| Movie | 2012 | Eldorado | General Zwick | |
| Movie | 1996 | Ghostlands | Edward Parfitt | |
| Movie | 2024 | The Apocalypse Box | Peter Mann | |
| Movie | 1987 | Doctor Who: Dragonfire | The Doctor | |
| Movie | 1987 | Doctor Who: Delta and the Bannermen | The Doctor | |
| Movie | 1987 | Doctor Who: Time and the Rani | The Doctor | |
| Movie | 1989 | Doctor Who: Ghost Light | The Doctor | |
| Movie | 1988 | Doctor Who: The Greatest Show in the Galaxy | The Doctor | |
| Movie | 1988 | Doctor Who: Silver Nemesis | The Doctor | |
| Movie | 1988 | Doctor Who: The Happiness Patrol | The Doctor | |
| Movie | 1988 | Doctor Who: Remembrance of the Daleks | The Doctor | |
| Movie | 1994 | Stranger than Fiction | | |
| Movie | 1995 | Stranger than Fiction 2: From Script to Screen | | |
| Movie | 1996 | Bidding Adieu: A Video Diary | Self | |
| Movie | 1995 | The Doctors: 30 Years of Time Travel and Beyond | | |
| Movie | 1995 | Leapin' Leprechauns | Flynn | |
| Movie | 2017 | Slumber | Amado | |
| Movie | 1987 | Three Kinds of Heat | Harry Pimm | |
| Movie | 2011 | Doctor Who: Tales Lost in Time | | |
| Movie | 2006 | Manilla Envelopes | Duncan | |
| Movie | 2001 | Do You Have a Licence to Save this Planet? | The Foot Doctor | |
| Movie | 1999 | Adventures in Space and Time | Himself | |
| Movie | 2007 | Davros Connections | (archival footage) | |
| Movie | 2003 | The Story of Doctor Who | | |
| Movie | 1996 | I Was a Doctor Who Monster! | Presenter | |
| Movie | 1997 | Beyond Fear | Michael Samms | |
| Movie | 1998 | Where on Earth Is Katy Manning? | | |
| Movie | 2020 | The Owners | Richard Huggins | |
| Movie | 2018 | Beauty | Henry | |
| Movie | 2020 | Lost at Christmas | Ernie | |
| Movie | 1971 | The Ken Campbell Roadshow | Self | |
| Movie | 1987 | Doctor Who: Paradise Towers | The Doctor | |
| Movie | 1991 | Thrill Kill Video Club | Spoons | |
| Movie | N/A | You - Story and Glory of a Masterpiece | Museum attendant / Vasilij Grossman | |
| Movie | 1980 | Electric in the City | Kerwin | |
| Movie | 2002 | Doctor Who: Death Comes to Time | The Doctor | |
| Movie | 2024 | Doctor Who at the Proms | The Doctor (7) (archive footage) | |
| Movie | 2025 | The Heartsmith | Umbrella Man | |
| Movie | 2018 | The Doctors: Monsters! | | |
| Movie | 1992 | The Children's Royal Variety Performance | The Wizard | |
| Movie | 1993 | 30 Years in the TARDIS | Himself | |
| Movie | 2008 | Doctor Who: The Next Doctor | The Doctor (7) (archive footage) | |
| Movie | 2015 | Doctor Who: The Husbands of River Song | The Doctor (7) (picture) (uncredited) | |
| Movie | 1993 | Police 5: The Master | The Doctor (archive footage) | |
| Movie | 1993 | I Was That Monster | Himself | |
| Movie | 1990 | Search Out Space | The Doctor | |
| Movie | 2007 | Doctor Who: Endgame | | |
| Movie | 1988 | The Making of Doctor Who: Silver Nemesis | | |
| Movie | 2013 | Doctor Who: Tales from the TARDIS | Self | |
| Movie | 2010 | The Last Chance Saloon | | |
| Movie | 2025 | Doctor Who: Downtime | The Doctor | |
| Movie | 2025 | Doctor Who: The Eight Doctors | The Doctor | |
| Movie | 2025 | Doctor Who: Wish World & The Reality War | The Doctor (archive footage) (uncredited) | |
| Movie | 2021 | Sylvester McCoy - In Conversation | Self | |
| TV Show | 1974 | Tiswas | | 302 |
| TV Show | 1964 | Vision On | | 121 |
| TV Show | 2002 | Still Game | | 1 |
| TV Show | 2005 | Doctor Who Confidential | | 9 |
| TV Show | 1984 | The Bill | | 1 |
| TV Show | 1997 | The History of Tom Jones: A Foundling | Mr, Dowling | 5 |
| TV Show | 1997 | Space Cadets | Self | 2 |
| TV Show | 2006 | Mayo | Reverend Beaver | 1 |
| TV Show | 1985 | The Last Place on Earth | Lt. 'Birdie' Bowers | 7 |
| TV Show | 1993 | GMTV | Self | 2 |
| TV Show | 1981 | Big Jim And The Figaro Club | Turps | 6 |
| TV Show | 1987 | It's Wicked | | 1 |
| TV Show | 2011 | Pointless Celebrities | Self | 1 |
| TV Show | 1978 | An Audience with... | Self | 1 |
| TV Show | 1993 | Frank Stubbs Promotes | Angus | 1 |
| TV Show | 1986 | Casualty | Kev the Rev | 1 |
| TV Show | 1986 | Casualty | Ashley Millington | 1 |
| TV Show | 2023 | Tales of the Tardis | The Doctor | 1 |
| TV Show | 1987 | Doctor Who Then & Now | Doctor Who | 1 |
| TV Show | 2013 | Father Brown | Dr. Angus McClurgy | 1 |
| TV Show | 1987 | Going Live! | Self | 2 |
| TV Show | 2016 | The Real Marigold Hotel | Self | 3 |
| TV Show | 2015 | Thunderbirds Are Go! | Aezethril the Wizard (voice) | 1 |
| TV Show | 1963 | Doctor Who | The Doctor | 42 |
| TV Show | 2013 | Doctor Who: The Doctors Revisited | Self | 11 |
| TV Show | 1974 | Playhouse | Kerwin | 1 |
