| Movie | 2009 | Special Correspondents | Jimmy | |
| Movie | 2004 | The Box | Lorenzo | |
| Movie | 2009 | Micmacs | Remington | |
| Movie | 2007 | Garage Babes | Hamidou | |
| Movie | 2002 | Samouraïs | Tyson | |
| Movie | 2009 | King Guillaume | Jean Peter | |
| Movie | 2007 | Omar et Fred - Le spectacle | Omar Sy | |
| Movie | 2009 | Safari | Youssouf Hammal | |
| Movie | 2002 | The Race | Sergent ONU | |
| Movie | 2014 | CANAL+'s 30th anniversary | Self | |
| Movie | 2006 | Those Happy Days | Joseph | |
| Movie | 2009 | Round Da Way | Narbé (voice) | |
| Movie | 2009 | Murphy's Law | Joachim Ortega / Father Joachim Ortega | |
| Movie | 2009 | So Happy Together | Bruno | |
| Movie | 2010 | The Storytelling Show | Momo (voice) | |
| Movie | 2011 | The Intouchables | Driss | |
| Movie | 2013 | L'entrée des Trappistes | Self | |
| Movie | 2010 | The Not-So-Little Thumbling | Grand Poucet | |
| Movie | 2022 | Drôles de familles | Self | |
| Movie | 2014 | X-Men: Days of Future Past | Bishop | |
| Movie | 2012 | On the Other Side of the Tracks | Ousmane Diakhité | |
| Movie | 2000 | Jamel Debbouze - Le très très bien de Jamel | Self | |
| Movie | 2011 | The Tuche Family | Le curé | |
| Movie | 2013 | Mood Indigo | Nicolas | |
| Movie | 2025 | Shadow Force | Isaac | |
| Movie | 2012 | The Dream Team | Wéké N’Dogo | |
| Movie | 2012 | Mais qui a re-tué Pamela Rose ? | Mosby | |
| Movie | 2023 | Father & Soldier | Bakary Diallo | |
| Movie | 2003 | The Dope | Michel Dembélé | |
| Movie | 2002 | If I Was Him | Gabriel | |
| Movie | 2014 | Good People | Khan | |
| Movie | 2015 | Jurassic World | Barry | |
| Movie | 2025 | Out of Control | Julien | |
| Movie | 2025 | I Was a Stranger | Marwan | |
| Movie | 2014 | Samba | Samba Cissé | |
| Movie | 2024 | The Killer | Sey | |
| Movie | 2020 | GIMS: On the Record | Self | |
| Movie | 2015 | Mune: Guardian of the Moon | Sohone (voice) | |
| Movie | 2016 | Inferno | Christoph Bouchard | |
| Movie | 2024 | The Book of Clarence | Barabbas | |
| Movie | N/A | Le Chat du rabbin | Le chat | |
| Movie | 2015 | Burnt | Michel | |
| Movie | 2008 | VERSUS | Self | |
| Movie | 2016 | Chocolat | Rafael Padilla, aka Chocolat | |
| Movie | 2025 | French Lover | Abel Camara | |
| Movie | 2004 | Coming-Out | Omar Sy | |
| Movie | 2002 | Ces jours heureux | Brice | |
| Movie | 2016 | Two Is a Family | Samuel | |
| Movie | 1999 | Jamel Show | Self | |
| Movie | 2019 | Arctic Dogs | Leopold (voice) | |
| Movie | 2001 | La Tour Montparnasse Infernale | Le Taxi | |
| Movie | 2011 | Marrakech du rire | Self | |
| Movie | 2017 | Sahara | Ajar (voice) | |
| Movie | 2017 | Knock | Knock | |
| Movie | 2016 | The Blues: Another Story of France | Self | |
| Movie | 2010 | Conte de la frustration | Mo | |
| Movie | 2017 | Transformers: The Last Knight | Hot Rod (voice) | |
| Movie | 2005 | Once Upon a Time in the Oued | le génie de la lampe | |
| Movie | 2019 | The Wolf's Call | D'Orsi | |
| Movie | 2017 | Au tableau - Edouard Philippe / Anne Hidalgo / Omar Sy | Self, Actor | |
| Movie | 2018 | Belleville Cop | Baaba Keita | |
| Movie | 2019 | Yao | Seydou Tall | |
| Movie | 2020 | The Lost Prince | Djibi, le père / le prince | |
| Movie | 2020 | The Call of the Wild | Perreault | |
| Movie | 2018 | Omar Sy, c'est ta chance | Self | |
| Movie | 2016 | Dans l'ombre de Teddy Riner | Himself | |
| Movie | 2020 | Refugee | Marwan | |
| Movie | 2018 | The Perfect Day | Self | |
| Movie | 2020 | Night Shift | Aristide | |
| Movie | 2020 | Simply Black | Omar Sy | |
| Movie | 2022 | Jurassic World Dominion | Barry Sembène | |
| Movie | 2010 | Florence Foresti : Mother Fucker | Taxi driver | |
| Movie | 2020 | Anelka: Misunderstood | Self | |
| Movie | 2002 | Dead Weight | Malian guy | |
| Movie | 2020 | La télé d'Omar et Fred | | |
| Movie | 2021 | Fake News | Starsky, the Uber driver | |
| Movie | 2008 | 2 Alone in Paris | Sammy Bouglioni | |
| Movie | 2004 | L'Année des Guignols - Un Jean-Pierre ça peut tout faire | Self - Impersonator (voices) | |
| Movie | 2000 | L'année des guignols - Ras le bol les guignols ! | Self - Impersonator (voices) | |
| Movie | 2022 | The Takedown | Ousmane Diakhité | |
| Movie | 2024 | Michel Denisot n'aime pas les anniversaires | Self | |
| Movie | 2027 | Dumas: Black Devil | | |
| Movie | 2025 | Patience (Sabali) | Sekou | |
| Movie | N/A | Patience | Sekou | |
| TV Show | 2021 | Lupin | Assane Diop | 17 |
| TV Show | 1990 | Fort Boyard | Self | 1 |
| TV Show | 2011 | Fish 'n' Chips | Fish (voix) | 52 |
| TV Show | 2021 | C ce soir, le débat | Self - Guest | 1 |
| TV Show | 2006 | Salut les Terriens ! | Self - Guest | 7 |
| TV Show | 2005 | SAV des émissions | | 162 |
| TV Show | 2011 | Bref | Omar Sy | 1 |
| TV Show | 2007 | Moot-Moot | Isidore (voice) | 15 |
| TV Show | 2022 | Cannes Festival | Self - Guest | 1 |
| TV Show | 2007 | Moot-Moot | Tanguy (voice) | 1 |
| TV Show | 2000 | La Cape et l'épée | Ménestrel | 1 |
| TV Show | 2008 | N'oubliez pas les paroles - Primes événementiels | Self | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 1 |
| TV Show | 1992 | Morgenmagazin | Self | 1 |
| TV Show | 2017 | Face the Classroom | Self - Guest | 1 |
| TV Show | 2021 | Humberto | Self | 1 |
| TV Show | 2016 | Quotidien | Self - Guest | 1 |
| TV Show | 2023 | Beau geste | Self | 1 |
| TV Show | N/A | Mercenary | | 0 |
| TV Show | 2001 | As An Aside | Self - Guest | 1 |
| TV Show | 2023 | Faut Voir - L'hebdo cinéma | Self - Guest | 1 |
| TV Show | 2022 | Sherri | Self - Guest | 1 |
| TV Show | 2019 | The Kelly Clarkson Show | Self | 1 |
| TV Show | 2022 | Les Rencontres du Papotin | Self | 1 |
| TV Show | 2018 | Bonsoir ! | Self - Guest | 1 |
| TV Show | 2006 | On n'est pas couché | Self - Guest | 1 |
