| Movie | 1984 | Gremlins | Gizmo (voice) | |
| Movie | 1990 | Gremlins 2: The New Batch | Gizmo (voice) | |
| Movie | 2020 | Julia Scotti: Funny That Way | Self (archive footage) | |
| Movie | 2021 | Back Home Again | Father Bear (voice) | |
| Movie | 2023 | The 10th Annual On Cinema Oscar Special | Self / Spencer from 'Pinocchio 3000' | |
| Movie | 2007 | Heckler | Self | |
| Movie | 1987 | Walk Like a Man | Bobo Shand | |
| Movie | 2000 | The Tangerine Bear: Home in Time for Christmas! | Jack (voice) | |
| Movie | 1983 | The First Howie Mandel Special | himself | |
| Movie | 1989 | Little Monsters | Maurice | |
| Movie | 2005 | The Aristocrats | Self | |
| Movie | 1990 | Mother Goose Rock 'n' Rhyme | Humpty Dumpty | |
| Movie | 1994 | In Search of Dr. Seuss | Sam-I-Am (voice) | |
| Movie | 1986 | A Fine Mess | Dennis Powell | |
| Movie | 2002 | Hansel & Gretel | The Sandman | |
| Movie | 2022 | The Disruptors | Self | |
| Movie | 2000 | Tribulation | Jason Quincy | |
| Movie | 1994 | Shake, Rattle and Rock! | Danny Klay | |
| Movie | 2004 | Pinocchio 3000 | Spencer (voice) | |
| Movie | 2006 | The Great Polar Bear Adventure | Pupa (voice) | |
| Movie | 2004 | Bobby's World The Signature Episodes | Bobby | |
| Movie | 2013 | When Jews Were Funny | | |
| Movie | 1986 | Howie Mandel: North American Watusi Tour | Himself | |
| Movie | 1985 | Where Did I Come From? | Narrator (voice) | |
| Movie | 2022 | Chop & Steele | Self | |
| Movie | 1988 | Joan Rivers and Friends Salute Heidi Abromowitz | Howie Mandel | |
| Movie | 2023 | Family Switch | Barry | |
| Movie | 1985 | Howie Mandel: Live from Carnegie Mall | Self | |
| Movie | 2001 | Spinning Out of Control | Marty Levinne | |
| Movie | 1994 | Magic Kid II | Moe | |
| Movie | 2015 | Being Canadian | Self | |
| Movie | 2015 | Impractical Jokers: Live Punishment Special | Self - Host | |
| Movie | 2015 | 7 Days in Hell | The Duke of Kent | |
| Movie | 2017 | Killing Hasselhoff | Self | |
| Movie | 1997 | Howie Mandel On Ice | Himself | |
| Movie | 1993 | David Copperfield | Mealy (voice) | |
| Movie | 2002 | Added Attractions: The Hollywood Shorts Story | Self (uncredited) | |
| Movie | 2024 | Miss Q | Self | |
| Movie | 2010 | 2Everything2Terrible2: Tokyo Drift | (archive footage) | |
| Movie | 1986 | The Princess Who Had Never Laughed | Wienerhead Waldo | |
| Movie | 1986 | The Young Comedians All-Star Reunion | Self | |
| Movie | 2017 | Gilbert | Self | |
| Movie | 1986 | The Canadian Conspiracy | | |
| Movie | 1981 | Gas | Matt Lloyd | |
| Movie | 1983 | The Funny Farm | Larry Pound | |
| Movie | 2017 | Night of Too Many Stars: America Unites for Autism Programs | Self | |
| Movie | 2017 | A Very Pentatonix Christmas | Self | |
| Movie | 2017 | Where Have You Gone, Lou DiMaggio? | Self | |
| Movie | 2018 | Narishkayt: YidLife Crisis in Krakow | | |
| Movie | 2018 | Darci Lynne: My Hometown Christmas | | |
| Movie | 2019 | Howie Mandel Presents Howie Mandel at the Howie Mandel Comedy Club | Himself | |
| Movie | 1992 | The Martin & Lewis Story: The Last Great Comedy Team | Self | |
| Movie | 2019 | I Am Richard Pryor | Self - Actor and Comedian | |
| Movie | 2018 | Game Changers | Self | |
| Movie | 1995 | Harrison Bergeron | Charlie | |
| Movie | 2020 | Howie Mandel's 5th Annual All-Star Gala | Self - Host | |
| Movie | 2000 | Timothy Tweedle the First Christmas Elf | Comet (voice) | |
| Movie | 2020 | Stronger Together, Tous Ensemble | Self | |
| Movie | 2020 | Feeding America Comedy Festival | Self | |
| Movie | 2020 | Penn & Teller: Try This at Home Too | Himself | |
| Movie | 2020 | Howie Mandel: But, Enough About Me | Self | |
| Movie | 2014 | From Gizmo to Gremlins: Creating the Creatures | Self | |
| Movie | 2014 | Committed | Self | |
| Movie | 2021 | Mister Candid Camera | Self | |
| Movie | 2026 | Pierre the Pigeon-Hawk | | |
| Movie | 2019 | Jeff Dunham: Talking Heads | Self | |
| Movie | 1999 | Jackie's Back! | Howie Mandel | |
| Movie | 1984 | Saturday's the Place! | Self (uncredited) | |
| Movie | 2024 | Gallagher | Self | |
| Movie | 1987 | The Best of Max Headroom | Self | |
| Movie | 1986 | The Ice Man Hummeth | Locker Room Guy | |
| Movie | 2025 | When We Went MAD! | Self | |
| Movie | N/A | The 6th Annual Young Comedians | Self | |
| TV Show | 2005 | Medium | Howie Mandel | 1 |
| TV Show | 1982 | St. Elsewhere | Wayne Fiscus | 137 |
| TV Show | 1992 | The Ben Stiller Show | | 1 |
| TV Show | 1969 | Sesame Street | | 1 |
| TV Show | 1985 | Larry King Live | Self | 1 |
| TV Show | 2003 | The Ellen DeGeneres Show | Self | 7 |
| TV Show | 1984 | Muppet Babies | Baby Animal / Baby Bunsen (voice) | 13 |
| TV Show | 2004 | The Tony Danza Show | Self | 2 |
| TV Show | 1999 | Providence | Self (uncredited) | 1 |
| TV Show | 2006 | Studio 60 on the Sunset Strip | Self | 1 |
| TV Show | 2002 | Monk | Ralph Roberts | 2 |
| TV Show | 1952 | Today | Self | 1 |
| TV Show | 1988 | LIVE with Kelly and Mark | Self | 4 |
| TV Show | 1993 | The Nanny | Howie Mandel | 1 |
| TV Show | 2003 | Las Vegas | Self | 1 |
| TV Show | 1992 | The Tonight Show with Jay Leno | Self | 11 |
| TV Show | 2015 | Superstore | Howie Mandel | 1 |
| TV Show | 2007 | Deal or No Deal Canada | Himself - Host | 5 |
| TV Show | 1995 | MADtv | Self | 1 |
| TV Show | 1982 | Faerie Tale Theatre | Wienerhead Waldo | 1 |
| TV Show | 1993 | Homicide: Life on the Street | Interior Decorator | 1 |
| TV Show | 2009 | The Jay Leno Show | Self | 1 |
| TV Show | 1993 | Late Night with Conan O'Brien | Self - Guest | 5 |
| TV Show | 2005 | Deal or No Deal | Self - Host | 234 |
| TV Show | 1992 | The Amazing Live Sea Monkeys | The Professor | 11 |
| TV Show | 2020 | The Comedy Store | Self | 5 |
| TV Show | 2007 | The Big Bang Theory | Howie Mandel | 1 |
| TV Show | 1990 | Carol & Company | Steve | 38 |
| TV Show | 2009 | Glenn Martin, DDS | | 1 |
| TV Show | 2010 | The Marriage Ref | Self - Panelist | 1 |
| TV Show | 2019 | The Masked Singer | Rock Lobster | 1 |
| TV Show | 1995 | The Outer Limits | Karl Durand | 1 |
| TV Show | 2008 | The Wendy Williams Show | | 1 |
| TV Show | 1988 | Friday Night Live | | 1 |
| TV Show | 2012 | Canada's Got Talent | Self - Judge | 0 |
| TV Show | 2009 | 2009 Game Show Awards | Self - Host | 1 |
| TV Show | 1990 | Good Grief | Ernie Lapidus | 13 |
| TV Show | 1995 | Bless This House | Stuart Wyler | 16 |
| TV Show | 2011 | Mobbed | Host | 11 |
| TV Show | 2019 | Game Changer | Self - Guest Judge | 1 |
| TV Show | 2019 | Tamron Hall | Self - Guest | 1 |
| TV Show | 2023 | The Game Show Show | Self | 4 |
| TV Show | 2006 | America's Got Talent | Self - Judge | 404 |
| TV Show | 1994 | Rebel Highway | Danny Klay | 10 |
| TV Show | 1982 | Faerie Tale Theatre | Guest Interviewee | 1 |
| TV Show | 2005 | The Late Late Show with Craig Ferguson | Self | 1 |
| TV Show | 2011 | Impractical Jokers | Self - Host | 1 |
| TV Show | 2012 | The Eric Andre Show | Self | 1 |
| TV Show | 2019 | America's Got Talent: The Champions | | 7 |
| TV Show | 2024 | America's Got Talent: Fantasy League | Self - Judge | 8 |
| TV Show | 2022 | Bullsh*t The Gameshow | Apresentador | 10 |
| TV Show | 2012 | Canada's Got Talent | Judge | 0 |
| TV Show | 2020 | Celebrity IOU | Self | 1 |
| TV Show | 2022 | Dark Side of Comedy | Self | 1 |
| TV Show | 1988 | LIVE with Kelly and Mark | Self - Guest | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 4 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self | 1 |
| TV Show | 2022 | The Kardashians | Self | 1 |
| TV Show | 2022 | The Jennifer Hudson Show | Self | 4 |
| TV Show | 2019 | The Kelly Clarkson Show | Self | 2 |
| TV Show | 1990 | Bobby's World | Bobby / Howard (voice) | 81 |
| TV Show | 1992 | Martin & Lewis: Their Golden Age of Comedy | Self | 3 |
| TV Show | 2019 | Biography: Comedy Icons | Himself | 1 |
| TV Show | 2005 | The Reichen Show | Self - Guest | 1 |
| TV Show | 2016 | Hollywood Medium with Tyler Henry | Self - Guest | 1 |
| TV Show | 2014 | Late Night with Seth Meyers | Self | 2 |
| TV Show | 2013 | Deal With It | Self | 5 |
| TV Show | 2006 | Comics Unleashed | Self | 2 |
| TV Show | 2009 | The Dr. Oz Show | | 1 |
| TV Show | 1962 | The Tonight Show Starring Johnny Carson | Self | 2 |
| TV Show | 1997 | The View | Self | 1 |
| TV Show | 2019 | The Kelly Clarkson Show | Self - Guest Host | 1 |
| TV Show | 2024 | Stupid Pet Tricks | Self | 1 |
| TV Show | 2005 | My Name Is Earl | Howie Mandel | 1 |
| TV Show | 2022 | The Checkup with Dr. David Agus | Self | 1 |
| TV Show | 2022 | Password | Self - Celebrity Guest | 1 |
| TV Show | 1993 | Lois & Clark: The New Adventures of Superman | Mr. Mxyzptlk | 1 |
| TV Show | 2023 | America's Got Talent: All-Stars | Self - Judge | 9 |
| TV Show | 2024 | Deal or No Deal Island | Self - Banker | 1 |
| TV Show | 2020 | The Search For Canada's Game Shows | Self | 7 |
| TV Show | 2003 | Real Time with Bill Maher | Self | 1 |
| TV Show | 2024 | Celebrity Family Food Battle | Self - Contestant | 1 |
| TV Show | 2020 | The Secret Life of Lele Pons | Himself | 1 |
| TV Show | 2019 | Harley Quinn | Howie Mandel (voice) | 1 |
| TV Show | 2024 | Rhett & Link's Wonderhole | Howie Mandel | 1 |
| TV Show | 2010 | Conan | Self | 3 |
| TV Show | 2006 | The Megan Mullally Show | Self - Guest | 1 |
| TV Show | 1944 | Golden Globe Awards | Self - Presenter | 1 |
| TV Show | 2023 | Dr Phil LIVE! | Self | 1 |
| TV Show | 2022 | Canada's Got Talent | Self - Judge | 36 |
| TV Show | 1985 | The Max Headroom Show | Self | 1 |
| TV Show | 2018 | The Fix | Self - Guest | 1 |
