| Movie | 2022 | Blank | Henry | |
| Movie | 2005 | Stuart Little 3: Call of the Wild | Reeko (voice) | |
| Movie | 2000 | Geppetto | The Magician | |
| Movie | 2006 | Crossover | Vaughn | |
| Movie | 2006 | The Adventures of Brer Rabbit | Brer Wolf (voice) | |
| Movie | 2005 | Roll Bounce | D.J. Johnny Feelgood | |
| Movie | 2004 | Clifford's Really Big Movie | Shackelford (voice) | |
| Movie | 2010 | Katt Williams: 9 Lives | Self | |
| Movie | 2010 | Wayne Brady Live - Making Shit Up | Himself | |
| Movie | 2004 | Going to the Mat | Mason Wyatt | |
| Movie | 2012 | Foodfight! | Daredevil Dan (voice) | |
| Movie | 2013 | 1982 | Alonso | |
| Movie | 2007 | The List | Lewis | |
| Movie | 2013 | Sofia the First: The Floating Palace | Clover (voice) | |
| Movie | 2014 | The Hero of Color City | Blue (voice) | |
| Movie | 1988 | Earth Girls Are Easy | Extra (uncredited) | |
| Movie | 2015 | Light Girls | Self | |
| Movie | 2024 | A Hip Hop Story | Freddy | |
| Movie | 2013 | Scooby-Doo! Stage Fright | Brick Pimiento (voice) | |
| Movie | 2015 | VeggieTales: Noah's Ark | Shem (voice) | |
| Movie | 2014 | Sofia the First: The Enchanted Feast | Clover (voice) | |
| Movie | 2012 | Comedy Central Roast of Roseanne | Self | |
| Movie | 2024 | Self Reliance | Wayne Brady | |
| Movie | 2005 | Jim Brickman at the Magic Kingdom: The Disney Songbook | Self | |
| Movie | 2016 | Straight Outta OZ | | |
| Movie | 2014 | Sofia the First: The Curse of Princess Ivy | Clover (voice) | |
| Movie | 2003 | The Electric Piper | Sly, The Electric Piper (voice) | |
| Movie | 2005 | Life O' The Party: On the Road with Prince and the New Power Generation | Self | |
| Movie | 2014 | Phineas and Ferb: Star Wars | Additional Voices (voice) | |
| Movie | 2019 | Laughing Matters | Self | |
| Movie | 2005 | I Do, They Don't | | |
| Movie | 2020 | Feeding America Comedy Festival | Self | |
| Movie | 2020 | Phineas and Ferb the Movie: Candace Against the Universe | Stapler-Fist / Additional Voices (voice) | |
| Movie | 2012 | Sofia the First: Once Upon a Princess | Clover (voice) | |
| Movie | 2020 | Blindfire | Davon | |
| Movie | 2021 | Ratatouille: The TikTok Musical | Django | |
| Movie | 2018 | Sofia the First: Forever Royal | Clover (voice) | |
| Movie | 2025 | Luke Null: Pretty Songs, Dirty Words | Self | |
| Movie | N/A | The Prince | | |
| Movie | 2004 | Sesame Street: What's the Name of That Song? | Self | |
| Movie | 2015 | Sofia The First: Dear Sofia...A Royal Collection | | |
| TV Show | 1999 | Batman Beyond | Micron (voice) | 2 |
| TV Show | 2005 | How I Met Your Mother | James Stinson | 13 |
| TV Show | 2005 | Everybody Hates Chris | Louis | 2 |
| TV Show | 2007 | Dirt | | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | | 1 |
| TV Show | 2005 | Nick Cannon Presents: Wild 'N Out | | 1 |
| TV Show | 1988 | LIVE with Kelly and Mark | | 1 |
| TV Show | 2005 | The Tyra Banks Show | | 1 |
| TV Show | 1972 | Dick Clark's New Year's Rockin' Eve with Ryan Seacrest | Self | 1 |
| TV Show | 2000 | Girlfriends | Derek Tyler | 4 |
| TV Show | 1997 | The View | Self | 5 |
| TV Show | 2019 | Tamron Hall | Self - Guest | 2 |
| TV Show | 2020 | Impractical Jokers: Dinner Party | Self | 1 |
| TV Show | 1992 | The Tonight Show with Jay Leno | | 1 |
| TV Show | 2001 | The Wayne Brady Show | | 11 |
| TV Show | 2021 | Game of Talents | Self - Host | 10 |
| TV Show | 2006 | 30 Rock | Steven | 1 |
| TV Show | 2006 | Shorty McShorts' Shorts | Cameron | 16 |
| TV Show | 1997 | Stargate SG-1 | Trelak | 1 |
| TV Show | 1995 | MADtv | Self | 1 |
| TV Show | 1995 | Star Search | | 1 |
| TV Show | 2018 | Black Lightning | Tyson Sykes / Gravedigger | 3 |
| TV Show | 2002 | The Anna Nicole Show | | 1 |
| TV Show | 2004 | Kevin Hill | Pastor Jerry Carver | 2 |
| TV Show | 1974 | The Daytime Emmy Awards | | 1 |
| TV Show | 2005 | Getting Along Famously | Jackie Kinghorn | 7 |
| TV Show | 2019 | The Masked Singer | Fox | 1 |
| TV Show | 2019 | The Masked Singer | Fox (archive footage) | 1 |
| TV Show | 2019 | A Black Lady Sketch Show | Reggie | 1 |
| TV Show | 2019 | The Masked Singer | Self - Guest Panelist | 1 |
| TV Show | 2014 | Last Week Tonight with John Oliver | Self | 1 |
| TV Show | 2003 | Reno 911! | New Jones - Deputy Culufu Garwood | 1 |
| TV Show | 2012 | Trust Us with Your Life | Himself | 8 |
| TV Show | 2017 | The Good Fight | Del Cooper | 6 |
| TV Show | 2013 | Sofia the First | Clover (voice) | 25 |
| TV Show | 2009 | Cubed | Wayne Brady | 0 |
| TV Show | 1974 | American Music Awards | Self - Host | 1 |
| TV Show | 2012 | Baby Daddy | Chase Baxter | 1 |
| TV Show | 2006 | Psych | Hilton Fox | 1 |
| TV Show | 2018 | Nailed It! | Self - Judge | 1 |
| TV Show | 1956 | Tony Awards | Self - Presenter | 1 |
| TV Show | 2023 | The Game Show Show | Self | 4 |
| TV Show | 2005 | American Dad! | Astronaut (voice) | 1 |
| TV Show | 2005 | American Dad! | Cuba Gooding Jr. (voice) | 1 |
| TV Show | 2005 | The Late Late Show with Craig Ferguson | Self | 1 |
| TV Show | 2005 | Hell's Kitchen | Self - Restaurant Patron | 1 |
| TV Show | 2022 | Make Some Noise | Self - Player | 1 |
| TV Show | 1998 | Whose Line Is It Anyway? | Self | 211 |
| TV Show | 2005 | Dancing with the Stars | Self - Contestant | 11 |
| TV Show | 2014 | Celebrity Name Game | Self | 3 |
| TV Show | 2022 | The Cuphead Show! | King Dice (voice) | 4 |
| TV Show | 1983 | Reading Rainbow | Himself - Narrator (voice) | 1 |
| TV Show | 2020 | The Drew Barrymore Show | Self | 1 |
| TV Show | 2017 | The F Word | Self | 1 |
| TV Show | 2007 | Phineas and Ferb | Guide (voice) | 1 |
| TV Show | 2016 | Match Game | Self - Panelist | 2 |
| TV Show | 2017 | Drop the Mic | Self | 1 |
| TV Show | 2013 | Hollywood Game Night | Self | 1 |
| TV Show | 2008 | Shatner's Raw Nerve | Self | 1 |
| TV Show | 2019 | American Soul | Little Richard | 1 |
| TV Show | 2022 | Right to Offend: The Black Comedy Revolution | Self | 2 |
| TV Show | 2010 | The Fran Drescher Show | | 1 |
| TV Show | 2006 | Comics Unleashed | Self | 2 |
| TV Show | 2024 | After Midnight | Self | 2 |
| TV Show | 2009 | Watch What Happens Live with Andy Cohen | Self - Guest | 3 |
| TV Show | 1998 | Hollywood Squares | | 10 |
| TV Show | 2018 | The Neighborhood | Isaiah Evans | 2 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self | 1 |
| TV Show | 1993 | Raw | | 1 |
| TV Show | 2016 | Milo Murphy's Law | Eugene (voice) | 1 |
| TV Show | 2020 | Stars in the House | Self | 1 |
| TV Show | 2019 | Lights Out with David Spade | Self - Panelist | 1 |
| TV Show | 2011 | Drew Carey's Improv-A-Ganza | Self | 40 |
| TV Show | 2022 | Sherri | Self - Guest | 1 |
| TV Show | 2015 | World's Funniest Fails | Self - Panelist | 1 |
| TV Show | 2013 | Whose Line Is It Anyway? | Self | 212 |
| TV Show | 2021 | Ziwe | | 1 |
| TV Show | 2003 | Comedy Central Roasts | Self | 1 |
| TV Show | 2007 | Don't Forget the Lyrics! | Self - Host | 3 |
| TV Show | 2005 | American Dad! | Tungee (voice) | 1 |
| TV Show | 2018 | Black Lightning | Gravedigger | 1 |
| TV Show | 2009 | RuPaul's Drag Race | Self - Guest Judge | 1 |
| TV Show | 2022 | American Gigolo | Lorenzo | 6 |
| TV Show | 2020 | Wayne Brady's Comedy IQ | | 10 |
| TV Show | 2019 | mixed-ish | Geoffrey | 1 |
| TV Show | 2024 | Wayne Brady: The Family Remix | Self | 8 |
| TV Show | 2015 | Celebrity Family Feud | Self | 1 |
| TV Show | 1988 | Whose Line Is It Anyway? | Himself | 5 |
| TV Show | 1995 | The Drew Carey Show | Wayne Brady | 2 |
| TV Show | 2016 | Colony | Everett Kynes | 8 |
| TV Show | 2009 | Let's Make a Deal | Self - Host | 2023 |
| TV Show | 2003 | Chappelle's Show | | 1 |
| TV Show | 2006 | The Megan Mullally Show | Self - Guest | 1 |
| TV Show | 2002 | American Dreams | Jackie Wilson | 1 |
| TV Show | 2024 | Is It Cake? Holiday | Self - Guest Judge | 1 |
| TV Show | 2012 | Key & Peele | Centipede Buddy | 1 |
| TV Show | 2022 | The Jennifer Hudson Show | Self | 1 |
| TV Show | 2005 | American Dad! | Wayne Brady (voice) | 1 |
| TV Show | 2005 | American Dad! | Major (voice) | 1 |
| TV Show | 1974 | American Music Awards | Self - Presenter | 1 |
