| Movie | 2008 | Delgo | Kurrin (voice) | |
| Movie | 2003 | Batman: Mystery of the Batwoman | Rocky (voice) | |
| Movie | 2010 | I'm Still Here | Kelly Ripa (uncredited) | |
| Movie | 2003 | Britney Spears: In the Zone | Self | |
| Movie | 1996 | Marvin's Room | Coral | |
| Movie | 2008 | Fly Me to the Moon | Nat's Mom (voice) | |
| Movie | 2008 | The Great Buck Howard | Kelly Ripa | |
| Movie | 2021 | Madame X Presents: Madame Xtra Q&A | Self | |
| Movie | 1999 | The Stand-In | Jennifer | |
| Movie | 2014 | Sharknado 2: The Second One | Kelly Ripa | |
| Movie | 2024 | Disney Legends Awards Ceremony | Self | |
| Movie | 2002 | Sesame Street: Elmo's World: Happy Holidays! | Mail Carrier Kelly | |
| Movie | 2002 | It's a Very Merry Muppet Christmas Movie | Self | |
| Movie | 2003 | Kim Possible: A Sitch In Time | Future Bonnie Rockwaller (voice) | |
| Movie | 2003 | Cheaper by the Dozen | Kelly Ripa | |
| Movie | 2020 | The Stand In | Kelly Ripa | |
| Movie | 2012 | The Perfect Human Diet | Self / Talk Show Host | |
| Movie | 2010 | Unforgettable | Self | |
| Movie | 2003 | Late Night with Conan O'Brien: 10th Anniversary Special | Self | |
| Movie | 2023 | Open Heart | Self (archive footage) | |
| Movie | 2025 | The Golden Girls: 40 Years of Laughter and Friendship | Self | |
| Movie | 2001 | Walt Disney World Very Merry Christmas Parade | Self - Host | |
| Movie | 2002 | Walt Disney World Christmas Day Parade | Self - Host | |
| Movie | 2003 | Walt Disney World Christmas Day Parade | Self - Host | |
| Movie | 2006 | Walt Disney World Christmas Day Parade | Self - Host | |
| Movie | 2005 | Walt Disney World Christmas Day Parade | Self - Host | |
| Movie | 2007 | Walt Disney World Christmas Day Parade | Self - Host | |
| Movie | 2008 | Walt Disney World Christmas Day Parade | Self - Host | |
| Movie | 2004 | Walt Disney World Christmas Day Parade | Self - Host | |
| Movie | 2009 | Disney Parks Christmas Day Parade | Self - Host | |
| TV Show | 1969 | Sesame Street | | 1 |
| TV Show | 2004 | The Ashlee Simpson Show | Self | 1 |
| TV Show | 2004 | The Tony Danza Show | Self | 1 |
| TV Show | 2006 | Brothers and Sisters | Kelly Ripa | 1 |
| TV Show | 1999 | Family Guy | Kelly Ripa (voice) | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 4 |
| TV Show | 1988 | LIVE with Kelly and Mark | Host | 0 |
| TV Show | 2000 | Ed | Jennifer Bradley | 4 |
| TV Show | 1997 | The View | Self | 5 |
| TV Show | 1995 | Road Rules | | 1 |
| TV Show | 2019 | Tamron Hall | Self - Guest | 1 |
| TV Show | 1996 | E! True Hollywood Story | | 1 |
| TV Show | 1993 | Late Night with Conan O'Brien | Self - Guest | 1 |
| TV Show | 2010 | The Marriage Ref | Self - Panelist | 3 |
| TV Show | 2001 | Popstars (US) | | 2 |
| TV Show | 2014 | Last Week Tonight with John Oliver | Self | 1 |
| TV Show | 2003 | TV Land Awards: A Celebration of Classic TV | | 1 |
| TV Show | 1975 | Saturday Night Live | Self - Host | 1 |
| TV Show | 1975 | Saturday Night Live | Self - Cameo (uncredited) | 2 |
| TV Show | 2014 | Broad City | Self | 1 |
| TV Show | 1992 | MTV Movie & TV Awards | Herself - Live with Kelly | 1 |
| TV Show | 2007 | CNN Heroes | Self - Host | 16 |
| TV Show | 2012 | Nashville | Herself | 1 |
| TV Show | 2014 | Late Night with Seth Meyers | Self | 2 |
| TV Show | 2003 | Hope & Faith | Faith Fairfield | 73 |
| TV Show | 1993 | Intimate Portrait | Self | 2 |
| TV Show | 2003 | Duck Dodgers | The New Cadet (voice) | 1 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self | 1 |
| TV Show | 1997 | The Wonderful World of Disney | Self - Host | 1 |
| TV Show | 2006 | 30 Rock | Kelly Ripa | 1 |
| TV Show | 2009 | Watch What Happens Live with Andy Cohen | Self - Guest | 16 |
| TV Show | 2022 | Generation Gap | Self - Host | 20 |
| TV Show | 2017 | Riverdale | Mrs. Mulwray | 1 |
| TV Show | 1988 | LIVE with Kelly and Mark | Self - Host | 4393 |
| TV Show | 2021 | Home Economics | Self | 1 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self - Guest | 2 |
| TV Show | 2006 | Hannah Montana | Kelly Ripa | 1 |
| TV Show | 1981 | Entertainment Tonight | Self | 3 |
| TV Show | 2013 | Alpha House | Self | 1 |
| TV Show | 2009 | Late Night with Jimmy Fallon | Self | 1 |
| TV Show | 2016 | American Housewife | Whitney (voice) | 4 |
| TV Show | 2007 | Say Yes to the Dress | Self | 1 |
| TV Show | 2025 | Running with the Wolves | Self | 4 |
| TV Show | 2006 | Ugly Betty | Kelly Ripa | 1 |
| TV Show | 2014 | Late Night with Seth Meyers | Self - Guest | 1 |
| TV Show | 2005 | Dancing with the Stars | Self - Video Message | 1 |
| TV Show | 2007 | Damages | Kelly Ripa | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self - Guest | 3 |
| TV Show | 2025 | My Nightmare Stalker: The Eva LaRue Story | Self - Co-Host, 'Live with Regis and Kelly' (archive footage) | 1 |
| TV Show | 1970 | All My Children | Hayley Vaughan | 407 |
