| Movie | 2008 | You Don't Mess with the Zohan | James T. O'Skanlon | |
| Movie | 2003 | Dave Matthews Band: The Central Park Concert | Dave Matthews | |
| Movie | 2001 | Dave Matthews Band: The Videos 1994-2001 | Dave Matthews | |
| Movie | 1999 | Dave Matthews Band: Listener Supported | Dave Matthews | |
| Movie | 2002 | Dave Matthews Band: Live at Folsom Field | Dave Matthews | |
| Movie | 2007 | Dave Matthews Band: Live at Piedmont Park | Dave Matthews | |
| Movie | 2005 | Dave Matthews Band: Weekend On The Rocks | Dave Matthews | |
| Movie | 2004 | Dave Matthews Band: The Gorge | Dave Matthews | |
| Movie | 2003 | Where the Red Fern Grows | Will Coleman | |
| Movie | 2003 | Go Further | Self | |
| Movie | 2008 | Lake City | Red | |
| Movie | 2000 | Santana: Supernatural Live | Self | |
| Movie | 2005 | Because of Winn-Dixie | Otis | |
| Movie | 2011 | Just Go with It | Ian Maxtone Jones | |
| Movie | 2009 | Dave Matthews Band - Across The Pond | | |
| Movie | 1999 | A Tribute To Johnny Cash | Self | |
| Movie | 2007 | Dave Matthews & Tim Reynolds - Live at Radio City Music Hall | Guitar, Vocals | |
| Movie | 2009 | Larger than Life in 3D | Himself | |
| Movie | 2010 | Hope for Haiti Now | Self | |
| Movie | 2009 | Dave Matthews Band: Live from the Beacon Theatre | Singer | |
| Movie | 2012 | Basically Frightened: The Musical Madness of Colonel Bruce Hampton | Self | |
| Movie | 2009 | Dave Matthews Band - Austin City Limits | | |
| Movie | 1995 | Dave Matthews Band - Rockpalast | Self | |
| Movie | 2023 | 2023 Rock & Roll Hall of Fame Induction Ceremony | Self | |
| Movie | 2013 | Life According to Sam | Self | |
| Movie | 2011 | A Child's Garden of Poetry | Self (voice) | |
| Movie | N/A | Dave Matthews Band: Comcast Theatre | Vocal | |
| Movie | 2017 | Dave Matthews Band - Concert for Charlottesville | Self | |
| Movie | 2022 | Homeward Bound: A Grammy Salute to the Songs of Paul Simon | Self | |
| Movie | N/A | Blue Man Group: Sing Along | | |
| Movie | 2007 | I Now Pronounce You Chuck & Larry | Salesman | |
| Movie | 2024 | Dave Matthews Band - Live in Lisbon, Portugal | | |
| Movie | 2012 | Dave Matthews Band: Away From the World | Himself | |
| Movie | 2023 | Willie Nelson 90: Long Story Short | Self | |
| Movie | 2001 | All Access: Front Row. Backstage. Live! | Self | |
| Movie | 2002 | Farm Aid 2001 - A Concert For America | Himself | |
| Movie | 2021 | Enormous: The Gorge Story | | |
| Movie | 2001 | America | A Tribute to Heroes | Self - Performer | |
| Movie | 2006 | Before the Music Dies | Self - Musician | |
| Movie | 2014 | Dave Matthews & Tim Reynolds - Farm Aid Live | | |
| Movie | 2014 | Dave Matthews Band Live From Jacksonville Arena | | |
| Movie | 2009 | Hard Rock Calling 2009 | Self | |
| Movie | 2018 | Semente da Música Brasileira | Self | |
| Movie | 2015 | Dave Matthews Band: Live Trax 36 - Alpine Valley Music Theatre | | |
| Movie | 2020 | Graduate Together: America Honors the High School Class of 2020 | Self | |
| Movie | 1997 | The Rolling Stones: Bridges to Babylon Tour '97-98 | Self | |
| Movie | 2024 | 2024 Rock & Roll Hall of Fame Induction Ceremony | Self | |
| TV Show | 2004 | House | Patrick Obyedkov | 1 |
| TV Show | 1992 | The Tonight Show with Jay Leno | | 1 |
| TV Show | 2005 | VH1 Storytellers | | 1 |
| TV Show | 2014 | Late Night with Seth Meyers | Self | 1 |
| TV Show | 2017 | Pete the Cat | Papi (voice) | 1 |
| TV Show | 1984 | MTV Video Music Awards | Self | 1 |
| TV Show | 1975 | Saturday Night Live | Self - Musical Guest | 5 |
| TV Show | 2002 | CMT Crossroads | Self | 1 |
| TV Show | 2008 | NPR Tiny Desk Concerts | Self | 1 |
| TV Show | 1989 | The Simpsons | Lloyd (voice) | 1 |
| TV Show | 2003 | Real Time with Bill Maher | Self | 1 |
| TV Show | 2015 | The Late Show with Stephen Colbert | Self | 1 |
