| Movie | 2022 | Tomorrow's Game | Jorge Robles | |
| Movie | 1986 | Quicksilver | Hector Rodriguez | |
| Movie | 2001 | Ali | Dr. Ferdie Pacheco | |
| Movie | 2001 | Crocodile Dundee in Los Angeles | Diego | |
| Movie | 2002 | Blood Work | Detective Ronaldo Arrango | |
| Movie | 2002 | The Original Latin Kings of Comedy | Himself | |
| Movie | 2001 | Rat Race | Gus the Cabbie | |
| Movie | 2007 | Heckler | Self | |
| Movie | 2004 | Baadasssss! | Jose Garcia | |
| Movie | 1983 | Belzer Behind Bars | Self | |
| Movie | 2010 | I Am Comic | Self | |
| Movie | 2008 | Beverly Hills Chihuahua | Chico (voice) | |
| Movie | 2001 | Tortilla Soup | Orlando Castillo | |
| Movie | 1986 | The Whoopee Boys | Barney Benar | |
| Movie | N/A | I'm Not Like That No More | | |
| Movie | 1991 | Voices That Care | Self - Choir Member | |
| Movie | 2003 | Time Changer | Eddie Martinez | |
| Movie | 1995 | Rough Magic | Diego | |
| Movie | 2001 | UFC 32: Showdown In The Meadowlands | Self | |
| Movie | 2006 | Cloud 9 | Mr. Wong | |
| Movie | 2005 | Back By Midnight | Next Week | |
| Movie | 1998 | Race | Gustavo Alvarez | |
| Movie | 1987 | Born in East L.A. | Javier | |
| Movie | 1995 | Paul Rodriguez: Live in San Quentin | Himself | |
| Movie | 2009 | Paul Rodriguez & Friends: Comedy Rehab | Himself | |
| Movie | 1986 | Ponce de Leon | Julio | |
| Movie | 1994 | A Million to Juan | Juan Lopez | |
| Movie | 2012 | Paul Rodriguez: Just for the Record | Himself | |
| Movie | 2000 | Mambo Café | Frank | |
| Movie | 2005 | El vacilón: The Movie | Paul Rodriguez | |
| Movie | 2000 | G-Men from Hell | Winford 'Weenie Man' | |
| Movie | 1986 | Miracles | Juan | |
| Movie | 2009 | Porndogs: The Adventures of Sadie | Bato | |
| Movie | 2022 | Dirty Daddy: The Bob Saget Tribute | Self | |
| Movie | 2010 | The Deported | Ernesto | |
| Movie | 1994 | Loco Slam | | |
| Movie | 1983 | D.C. Cab | Xavier | |
| Movie | 2016 | Americano | El Divino | |
| Movie | 1997 | Rodney Dangerfield's 75th Birthday Toast | Self | |
| Movie | 2001 | Laughing Out Loud: America's Funniest Comedians | Self (archive footage) | |
| Movie | 1992 | Time Out: The Truth About HIV, AIDS and You | Self | |
| Movie | 2014 | Mission Air | General Raul | |
| Movie | 2006 | Holidaze: The Christmas That Almost Didn't Happen | Mr. C (voice) | |
| Movie | 1991 | La Pastorela: The Shepherd's Tale | Satanas | |
| Movie | 2022 | A Marriage Made in Heaven | Manuel Velosco | |
| Movie | 2023 | Gone Before His Time: Freddie Prinze Sr. | Self | |
| Movie | 2000 | Price of Glory | Pepe | |
| Movie | 2003 | Chasing Papi | Costas Delgado | |
| Movie | 2010 | Cats & Dogs: The Revenge of Kitty Galore | Crazy Carlito (voice) | |
| Movie | 2004 | A Cinderella Story | Bobby | |
| Movie | 2011 | Without Men | Camacho | |
| Movie | 2015 | Gravy | Chuy | |
| Movie | 2017 | Sandy Wexler | Testimonial | |
| Movie | 2017 | Pray for Rain | Francisco Reynoso | |
| Movie | 2005 | The World's Fastest Indian | Fernando | |
| Movie | 2018 | Armed | Hector | |
| Movie | 2006 | Inside Project 8: The Video Game | Self | |
| Movie | 2016 | Voiceless | | |
| Movie | 2018 | Paul Rodriguez: The Here & Wow | Himself | |
| Movie | 2018 | The Griddle House | Amos | |
| Movie | 2019 | The Curse of La Llorona | Officer Claro | |
| Movie | 1991 | Hi Honey - I'm Dead | Ralph, The Angel | |
| Movie | 2019 | Loves Me, Loves Me Not | Principal Davis | |
| Movie | 2019 | Ruta Madre | Flaco | |
| Movie | 1990 | Grand Slam | Pedro Gomez | |
| Movie | 1994 | Rhythm Thief | Eladio | |
| Movie | 2020 | Chateau Vato | Gustavo | |
| Movie | 2000 | Ready to Run | T.J. (voice) | |
| Movie | 1993 | Made in America | Jose | |
| Movie | 2022 | Silent Life: The Story of the Lady in Black | Alexander De Salm | |
| Movie | 2021 | Clifford the Big Red Dog | Sanchez | |
| Movie | 1988 | An All-Star Toast to the Improv | Self | |
| Movie | 1989 | Comic Relief III | Self | |
| Movie | 2024 | Holy Cash | Actor | |
| Movie | 1987 | Paul Rodriguez Live!: I Need the Couch | Self | |
| Movie | 1988 | Sid & Marty Krofft's Redeye Express | | |
| TV Show | 2005 | Kathy Griffin: My Life on the D-List | Self | 1 |
| TV Show | 1985 | The Golden Girls | Ramone | 1 |
| TV Show | 1994 | Touched by an Angel | Ben Rivera | 1 |
| TV Show | 1997 | King of the Hill | Jacinto (voice) | 1 |
| TV Show | 1996 | E! True Hollywood Story | | 1 |
| TV Show | 1993 | Late Night with Conan O'Brien | Self - Comedy Guest | 1 |
| TV Show | 1984 | a.k.a. Pablo | Paul Rivera | 6 |
| TV Show | 2020 | The Comedy Store | Self | 5 |
| TV Show | 1988 | Trial and Error | Tony Rivera | 8 |
| TV Show | 1998 | ALMA Awards | | 2 |
| TV Show | 1990 | Grand Slam (US) | Pedro Gomez | 8 |
| TV Show | 1999 | It's Christopher Lowell | | 1 |
| TV Show | 2002 | The Twilight Zone | Rosas | 1 |
| TV Show | 2022 | Dark Side of Comedy | Self | 1 |
| TV Show | 2012 | Fixing a Paco | | 9 |
| TV Show | 2012 | Gotham Comedy Live | Self - Host | 2 |
| TV Show | 2000 | Latin Grammy Awards | Self | 1 |
| TV Show | 2005 | The Buzz on Maggie | Julio's Father (voice) | 1 |
| TV Show | 1995 | Happily Ever After: Fairy Tales for Every Child | Jesse (voice) | 1 |
| TV Show | 1995 | Happily Ever After: Fairy Tales for Every Child | Gilbert the Fish (voice) | 1 |
| TV Show | 1995 | Happily Ever After: Fairy Tales for Every Child | Tizoc (voice) | 1 |
| TV Show | 1985 | Tall Tales & Legends | Julio | 1 |
| TV Show | 2018 | A Million Little Things | Javier Mendez | 4 |
| TV Show | 2012 | The First Family | Dictator Rafael | 1 |
| TV Show | 1962 | The Tonight Show Starring Johnny Carson | Self | 2 |
| TV Show | 2007 | Thank God You're Here | Self | 1 |
| TV Show | 1982 | Gloria | Jerry | 1 |
| TV Show | 2006 | The Megan Mullally Show | Self - Guest | 1 |
