| Movie | 2005 | Dave Chappelle's Block Party | Self | |
| Movie | 1997 | Con Air | "Pinball" Parker | |
| Movie | 2021 | Dave Chappelle: The Closer | Self | |
| Movie | 2004 | Dave Chappelle: For What It's Worth | Self | |
| Movie | 1999 | Blue Streak | Tulley | |
| Movie | 2021 | Madonna: Madame X | Self | |
| Movie | 2015 | Comedy Central Roast of Justin Bieber | Self | |
| Movie | 1993 | Robin Hood: Men in Tights | Ahchoo | |
| Movie | 1993 | Undercover Blues | Ozzie | |
| Movie | 2021 | Stunted | Self | |
| Movie | 2002 | Undercover Brother | Conspiracy Brother | |
| Movie | 1998 | Half Baked | Thurgood Jenkins / Sir Smoke-a-Lot | |
| Movie | 1998 | You've Got Mail | Kevin Jackson | |
| Movie | 1996 | The Nutty Professor | Reggie Warrington | |
| Movie | 2003 | Richard Pryor: I Ain't Dead Yet, #*%$#@!! | Self | |
| Movie | 2023 | Chris Rock: Road To Live Special | Self | |
| Movie | 2009 | Just for Laughs: Launching Pad | | |
| Movie | 1998 | Dave Chappelle: HBO Comedy Half-Hour | Self | |
| Movie | 1998 | The Real Blonde | Zee | |
| Movie | 1999 | 200 Cigarettes | Disco Cabbie | |
| Movie | 2021 | 2021 Rock & Roll Hall of Fame Induction Ceremony | Self | |
| Movie | 2000 | Dave Chappelle: Killin' Them Softly | Self | |
| Movie | 2000 | Screwed | Rusty P. Hayes | |
| Movie | 1999 | Funny Is Money | Self | |
| Movie | 1994 | Getting In | Ron | |
| Movie | 2016 | The Last Laugh | Self | |
| Movie | 2022 | The Hall: Honoring the Greats of Stand-Up | Self | |
| Movie | 2022 | Norm Macdonald: Nothing Special | Self | |
| Movie | 2022 | Dirty Daddy: The Bob Saget Tribute | Self | |
| Movie | 2022 | Dave Chappelle: What's in a Name? | Self | |
| Movie | 1997 | Mother Goose: A Rappin' and Rhymin' Special | The Spider (voice) | |
| Movie | 2022 | The Greatest Lie Ever Sold | Self (archive footage) | |
| Movie | 2022 | Taylor Hawkins Tribute Concert | Self | |
| Movie | 2023 | Dave Chappelle: The Dreamer | Self | |
| Movie | 2005 | Just for Laughs Stand Up, Vol. 1: Best of the Uptown Comics | Himself | |
| Movie | 1998 | Woo | Lenny | |
| Movie | 2002 | Hip-Hop Honeys | Himself | |
| Movie | 1998 | Bowl of Pork | Black Forrest Gump | |
| Movie | 2022 | 2022 Rock & Roll Hall of Fame Induction Ceremony | Self | |
| Movie | 2021 | Chris Rock Total Blackout: The Tamborine Extended Cut | Self (archive footage) | |
| Movie | 2015 | Chi-Raq | Morris | |
| Movie | 2013 | Richard Pryor: Omit the Logic | Self | |
| Movie | 2014 | New World Order: Communism by the Backdoor | Self (archive footage) | |
| Movie | 2016 | David Blaine: Beyond Magic | Self | |
| Movie | 2017 | Dave Chappelle: Deep in the Heart of Texas | Self | |
| Movie | 2017 | Dave Chappelle: The Age of Spin | Self | |
| Movie | 1996 | Prince: Love 4 One Another | | |
| Movie | 2005 | Life O' The Party: On the Road with Prince and the New Power Generation | Self | |
| Movie | 2018 | A Star Is Born | George "Noodles" Stone | |
| Movie | 2017 | Dave Chappelle: Equanimity | Self | |
| Movie | 2017 | Dave Chappelle: The Bird Revelation | Self | |
| Movie | 2016 | BET Presents Love & Happiness: An Obama Celebration | Self | |
| Movie | 2018 | Back To School Just For Laughs | Self | |
| Movie | 2019 | Fyre Fraud | Himself (Archival Footage) | |
| Movie | 2018 | The Road to Stardom: The Making of A Star Is Born | Self | |
| Movie | 2018 | Quincy | Self | |
| Movie | 2000 | Def Comedy Jam, Vol. 7 | | |
| Movie | 2019 | Dave Chappelle: Sticks & Stones | Self | |
| Movie | 2017 | Def Comedy Jam 25 | Self | |
| Movie | 1996 | Joe's Apartment | Cockroach (voice) | |
| Movie | 2018 | Q85: A Musical Celebration for Quincy Jones | Self | |
| Movie | 1993 | 'Robin Hood: Men in Tights' – The Legend Had It Coming | Self | |
| Movie | 2020 | David Blaine: The Magic Way | Self | |
| Movie | 2020 | 8:46 | Self | |
| Movie | 2019 | Epilogue: The Punchline | Self | |
| Movie | 2020 | 537 Votes | Self (archive footage) | |
| Movie | 2006 | World's Greatest Stand Up: Volume One | self | |
| Movie | 2020 | Dave Chappelle: Unforgiven | Self | |
| Movie | 2021 | Dave Chappelle: Redemption Song | Self | |
| Movie | 2019 | Before They Were Kings: Vol. 2 | | |
| Movie | 2019 | Devil's Pie: D'Angelo | Self | |
| Movie | 2021 | The One and Only Dick Gregory | Self | |
| Movie | 2021 | Dave Chappelle: Live in Real Life | Self | |
| Movie | 2025 | Ladies & Gentlemen... 50 Years of SNL Music | Self | |
| Movie | 2006 | September in Brooklyn: The Making of Block Party | Self | |
| Movie | 2019 | Dave Chappelle: The Kennedy Center Mark Twain Prize for American Humor | Self | |
| TV Show | 1994 | Inside the Actors Studio | Self | 1 |
| TV Show | 1991 | Home Improvement | Dave | 1 |
| TV Show | 2002 | Tough Crowd with Colin Quinn | | 57 |
| TV Show | 1996 | The Daily Show | Self | 2 |
| TV Show | 1992 | The Tonight Show with Jay Leno | | 1 |
| TV Show | 1975 | Saturday Night Live | Self - Host | 4 |
| TV Show | 1993 | Late Night with Conan O'Brien | Self - Guest | 6 |
| TV Show | 2003 | Wanda at Large | | 1 |
| TV Show | 2003 | Wanda at Large | Vincent | 19 |
| TV Show | 1996 | Buddies | Dave Carlisle | 13 |
| TV Show | 2005 | Iconoclasts | Self | 1 |
| TV Show | 2022 | jeen-yuhs: A Kanye Trilogy | Self (archive footage) | 1 |
| TV Show | 1996 | Where's Elvis This Week? | | 1 |
| TV Show | 2003 | Chappelle's Show | Host / Various Characters | 28 |
| TV Show | 2022 | Phat Tuesdays: The Era of Hip Hop Comedy | Self | 3 |
| TV Show | 1998 | Hollywood Squares | Self - Panelist | 5 |
| TV Show | 2017 | Dave Chappelle | Self | 2 |
| TV Show | 1995 | Happily Ever After: Fairy Tales for Every Child | The Spider (voice) | 1 |
| TV Show | 1987 | Biography | Himself (archival footage) | 1 |
| TV Show | 1996 | The Rosie O'Donnell Show | Self | 1 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self | 1 |
| TV Show | 2012 | Comedians in Cars Getting Coffee | Self | 1 |
| TV Show | 2019 | Will Smith's Bucket List | Himself | 1 |
| TV Show | 2016 | Ride with Norman Reedus | Self | 1 |
| TV Show | 1975 | Saturday Night Live | Self - Cameo (uncredited) | 2 |
| TV Show | 1994 | HBO Comedy Half Hour | Self | 1 |
| TV Show | 2018 | My Next Guest Needs No Introduction with David Letterman | Self | 1 |
| TV Show | 1999 | Mark Twain Prize | Self | 1 |
| TV Show | 2024 | Stand-Up: The Laughing Therapy | Self (archive footage) | 1 |
| TV Show | 1975 | Saturday Night Live | Self | 1 |
| TV Show | 1995 | Dr. Katz, Professional Therapist | Dave (voice) | 1 |
| TV Show | 1959 | The Grammys | Self | 1 |
| TV Show | 1989 | 1/2 Hour Comedy Hour | self | 1 |
