| Movie | 1996 | Fargo | Jerry Lundegaard | |
| Movie | 2001 | Jurassic Park III | Paul Kirby | |
| Movie | 1999 | Magnolia | Quiz Kid Donnie Smith | |
| Movie | 1997 | Wag the Dog | CIA Agent Charles Young | |
| Movie | 1995 | Mr. Holland's Opus | Vice Principal Gene Wolters | |
| Movie | 2007 | He Was a Quiet Man | Gene Shelby | |
| Movie | 2006 | Inland Empire | Announcer | |
| Movie | 2007 | Lynch 2 | Self | |
| Movie | 1998 | Pleasantville | George Parker | |
| Movie | 1994 | The Client | Dr. Greenway | |
| Movie | 2006 | Bobby | Paul Ebbers | |
| Movie | 2003 | The Cooler | Bernie Lootz | |
| Movie | 1993 | Benny & Joon | Randy Burch | |
| Movie | 2008 | Bart Got a Room | Ernie Stein | |
| Movie | 2003 | Seabiscuit | Tick Tock McGlaughlin | |
| Movie | 2004 | Spartan | Stoddard | |
| Movie | 1996 | Andersonville | Col. Chandler | |
| Movie | 1997 | Boogie Nights | Little Bill | |
| Movie | 2000 | Panic | Alex | |
| Movie | 2007 | Wild Hogs | Dudley Frank | |
| Movie | 2024 | Ricky Stanicky | Summerhayes | |
| Movie | 1998 | The Secret of NIMH 2: Timmy to the Rescue | Justin (voice) | |
| Movie | 2000 | State and Main | Walt Price | |
| Movie | 1991 | Homicide | Tim Sullivan | |
| Movie | 1998 | Psycho | Milton Arbogast | |
| Movie | 2005 | Sahara | Admiral Jim Sandecker | |
| Movie | 1999 | Happy, Texas | Sheriff Chappy Dent | |
| Movie | 2009 | The Maiden Heist | George McLendon | |
| Movie | 2004 | In Enemy Hands | Nathan Travers | |
| Movie | 1995 | Above Suspicion | Pros. Atty. Schultz | |
| Movie | 1996 | Ghosts of Mississippi | Charlie Crisco | |
| Movie | 1995 | Murder in the First | Bill McNeill | |
| Movie | 1984 | The Dining Room | Various | |
| Movie | 2006 | Doogal | Brian (voice) | |
| Movie | 2009 | Shorts | Dr. Noseworthy | |
| Movie | 1998 | A Civil Action | James Gordon | |
| Movie | 1996 | Down Periscope | Captain Knox | |
| Movie | 2004 | Cellular | Sgt. Bob Mooney | |
| Movie | 1994 | Oleanna | John | |
| Movie | 1997 | Air Force One | Major Caldwell | |
| Movie | 1999 | Mystery Men | Shoveler / Eddie | |
| Movie | 2005 | Thank You for Smoking | Senator Ortolan Finistirre | |
| Movie | 1987 | House of Games | Sgt. John Moran | |
| Movie | 2002 | It's a Very Merry Muppet Christmas Movie | Glenn | |
| Movie | 2002 | Door to Door | Bill Porter | |
| Movie | 1993 | Searching for Bobby Fischer | Tunafish Father | |
| Movie | 2006 | Everyone's Hero | Lefty Maginnis (voice) | |
| Movie | 1999 | A Slight Case of Murder | Terry Thorpe | |
| Movie | 2003 | Stealing Sinatra | John Irwin | |
| Movie | 2008 | The Deal | Charlie Berns | |
| Movie | 2004 | Reversible Errors | Arthur Raven | |
| Movie | 1995 | Evolver | Evolver (voice) | |
| Movie | 1996 | Hit Me | Policeman | |
| Movie | 2009 | Heath Ledger: A Tribute | Self | |
| Movie | 2005 | Edmond | Edmond | |
| Movie | 1992 | The Heart of Justice | Booth | |
| Movie | 2011 | The Lincoln Lawyer | Frank Levin | |
| Movie | 1993 | Twenty Bucks | Property Clerk | |
| Movie | 2010 | Dirty Girl | Ray | |
| Movie | 1992 | The Water Engine | Charles Lang | |
| Movie | 2004 | The Wool Cap | Gigot | |
| Movie | 1998 | Jerry and Tom | Karl | |
| Movie | 1997 | Colin Fitz | Mr. O'Day | |
| Movie | 1980 | Foolin' Around | Bronski | |
| Movie | 2003 | Minnesota Nice | Self | |
| Movie | 2012 | The Sessions | Father Brendan | |
| Movie | 1998 | The Con | Bobby | |
| Movie | 2013 | A Single Shot | Pitt | |
| Movie | 1994 | Dead on Sight | Steven Meeker | |
| Movie | 2023 | Maybe I Do | Sam | |
| Movie | 2013 | Trust Me | Gary | |
| Movie | 2013 | Citizen Hearst | Narrator | |
| Movie | 2014 | Two-Bit Waltz | Carl | |
| Movie | 2014 | Rudderless | Trill | |
| Movie | 2001 | Focus | Lawrence 'Larry' Newman | |
| Movie | 2001 | The Making Of Jurassic Park III | Self | |
| Movie | 2025 | Soul on Fire | | |
| Movie | 2007 | Curious George: Rocket Ride and Other Adventures | | |
| Movie | 2014 | Cake | Leonard | |
| Movie | 1998 | Macy On Mamet | | |
| Movie | 2008 | The Tale of Despereaux | Lester (voice) | |
| Movie | 2015 | Room | Robert | |
| Movie | 2015 | Walter | Dr. Corman | |
| Movie | 2015 | Dial a Prayer | Bill | |
| Movie | 2016 | Blood Father | Kirby Curtis | |
| Movie | 1983 | WarGames | NORAD Officer (uncredited) | |
| Movie | 1984 | The Boy Who Loved Trolls | Socrates | |
| Movie | 2016 | Stealing Cars | Philip Wyatt | |
| Movie | 1985 | The Last Dragon | J.J. | |
| Movie | 2024 | Kingdom of the Planet of the Apes | Trevathan | |
| Movie | 2011 | Portraits in Dramatic Time | | |
| Movie | N/A | The Deputy | Chief Krueger | |
| Movie | N/A | Exit Right | John Randall | |
| Movie | 2018 | Krystal | Wyatt | |
| Movie | 1992 | In the Line of Duty: Siege at Marion | Ray Daniels | |
| Movie | 2010 | Marmaduke | Don Twombly | |
| Movie | 2000 | Psycho Path | Self - Actor / Milton Arbogast | |
| Movie | 1980 | Somewhere in Time | Critic | |
| Movie | 2003 | Easy Riders, Raging Bulls: How the Sex 'n' Drugs 'n' Rock 'n' Roll Generation Saved Hollywood | Self - Narrator (voice) | |
| Movie | 1994 | Being Human | Boris | |
| Movie | 1992 | A Murderous Affair: The Carolyn Warmus Story | Sean Hammel | |
| Movie | 1999 | Batman Beyond: Tech Wars / Disappearing Inque | Aaron Herbst | |
| Movie | 2000 | That Moment: Magnolia Diary | Self | |
| Movie | 2006 | Choose Your Own Adventure: The Abominable Snowman | Rudyard North (voice) | |
| Movie | 2012 | Curious George: Saves the Day | The Narrator (voice) | |
| Movie | 1996 | The Writing on the Wall | Petrocelli | |
| Movie | 1995 | Roommates | Doctor (uncredited) | |
| Movie | 1999 | The Night of the Headless Horseman | Ichabod Crane | |
| Movie | 1988 | Things Change | Billy Drake | |
| Movie | 1988 | Lip Service | Farmer | |
| Movie | 1995 | In the Shadow of Evil | Dr. Frank Teague | |
| Movie | 1992 | A Private Matter | Psychiatrist | |
| Movie | 2006 | Unfiltered Comedy: The Making of 'Thank You For Smoking' | Self | |
| Movie | 1991 | Shadows and Fog | Cop | |
| Movie | 1987 | Radio Days | Radio Voice (voice) | |
| Movie | 1991 | Barton Fink | Navy Sailor (uncredited) | |
| Movie | 2018 | Lady Luck: The Making of The Cooler | Self | |
| Movie | 1995 | Tall Tale: The Unbelievable Adventure | Railroad Magnate | |
| Movie | 1983 | Without a Trace | Reporter | |
| Movie | 2011 | Return to Jurassic Park | Self | |
| Movie | 1983 | The Cradle Will Fall | Ben Duffy | |
| Movie | 2025 | The Running Man | | |
| Movie | N/A | Frontier Crucible | | |
| Movie | 2025 | Train Dreams | | |
| Movie | 2019 | Beyond the Headlines: The College Admissions Scandal with Gretchen Carlson | Self | |
| Movie | 2003 | The True Story of Seabiscuit | Narrator (voice) | |
| Movie | N/A | Brian | | |
| Movie | 2002 | Welcome to Collinwood | Riley | |
| TV Show | 1986 | L.A. Law | Bernard Ruskin | 1 |
| TV Show | 1999 | Batman Beyond | Aaron Herbst (voice) | 1 |
| TV Show | 1994 | Inside the Actors Studio | Self | 1 |
| TV Show | 1990 | Law & Order | Assistant U.S. Attorney John McCormack | 1 |
| TV Show | 1984 | Kate & Allie | | 1 |
| TV Show | 2003 | The Ellen DeGeneres Show | Self | 1 |
| TV Show | 1985 | Spenser: For Hire | | 2 |
| TV Show | 2006 | Curious George | Narrator (voice) | 60 |
| TV Show | 2003 | Jimmy Kimmel Live! | | 1 |
| TV Show | 2006 | The Unit | President of the United States | 1 |
| TV Show | 1998 | Sports Night | | 6 |
| TV Show | 1997 | The View | Self | 1 |
| TV Show | 1992 | The Tonight Show with Jay Leno | Self | 4 |
| TV Show | 2012 | Finding Your Roots | Self | 1 |
| TV Show | 1985 | The Equalizer | Dr. Spaulding | 1 |
| TV Show | 1996 | Superman: The Animated Series | Director (voice) | 1 |
| TV Show | 1995 | MADtv | Self | 1 |
| TV Show | 1994 | ER | David Morgenstern | 35 |
| TV Show | 1993 | Bakersfield P.D. | Russell Karp | 1 |
| TV Show | 2005 | The Late Late Show with Craig Ferguson | Self | 1 |
| TV Show | 2003 | Out of Order | Steven | 5 |
| TV Show | 1953 | The Oscars | Self | 1 |
| TV Show | 2001 | Good Day Live | Self | 1 |
| TV Show | 2011 | Shameless | Frank Gallagher | 134 |
| TV Show | 1998 | The Wild Thornberrys | Skoot (voice) | 1 |
| TV Show | 1999 | Batman Beyond | Karros (voice) | 1 |
| TV Show | 1993 | Frasier | Ralph (voice) | 1 |
| TV Show | 1978 | The Awakening Land | Will Beagle | 3 |
| TV Show | 1990 | Law & Order | Jack Powell | 1 |
| TV Show | 1988 | The Murder of Mary Phagan | Randy | 2 |
| TV Show | 2022 | The Dropout | Richard Fuisz | 5 |
| TV Show | 2009 | Watch What Happens Live with Andy Cohen | Self - Guest | 1 |
| TV Show | 2020 | Shameless Hall of Shame | Frank Gallagher | 1 |
| TV Show | 2006 | Nightmares & Dreamscapes: From the Stories of Stephen King | Clyde Umney / Sam Landry / George Demmick | 1 |
| TV Show | 1998 | The Lionhearts | Leo (voice) | 13 |
| TV Show | 1997 | King of the Hill | Dr. Rubin (voice) | 1 |
| TV Show | 1989 | The Simpsons | William H. Macy (voice) | 1 |
| TV Show | 1996 | Andersonville | Col. Chandler | 2 |
| TV Show | 2015 | Close Up with The Hollywood Reporter | Self | 1 |
| TV Show | 2014 | Off Camera with Sam Jones | Self | 1 |
| TV Show | 2010 | Conan | Self | 1 |
| TV Show | 2023 | Accused | Raymond | 1 |
| TV Show | 1985 | Alive from Off Center | unknown | 1 |
