| Movie | 2004 | Team America: World Police | Chris / George Clooney / Danny Glover / Ethan Hawke (voice) | |
| Movie | 1998 | Orgazmo | Dave the Lighting Guy | |
| Movie | 1999 | South Park: Bigger, Longer & Uncut | Kyle Broflovski / Kenny McCormick / Saddam Hussein / Terrance Henry Stoot / Big Gay Al / Ticket Taker / Stuart McCormick / Jimbo Kearn / Gerald Broflovski / Butters Stotch / Additional Voices (voice) | |
| Movie | 2021 | South Park: Post COVID | Various Characters (voice) | |
| Movie | 1996 | Cannibal! The Musical | James Humphries | |
| Movie | 1989 | First Date | Billy | |
| Movie | 1989 | Man on Mars | Chuck | |
| Movie | 1999 | Terror Firmer | Hermaphrodite (uncredited) | |
| Movie | 1998 | BASEketball | Doug Remer | |
| Movie | 2005 | The Aristocrats | Kyle / Kenny (voice) | |
| Movie | 2021 | South Park: Post COVID: The Return of COVID | Various Characters (voice) | |
| Movie | 2008 | South Park: Imaginationland | Various Characters (voice) | |
| Movie | 2006 | This Film Is Not Yet Rated | Self - Producer of 'South Park' and 'Team America' | |
| Movie | 1992 | The Spirit of Christmas: Jesus vs. Frosty | Boy 2 / Boy 3 (voice) | |
| Movie | 1995 | The Spirit of Christmas: Jesus vs. Santa | Kyle Broflovski / Kenny McCormick / Jesus (voice) | |
| Movie | 2011 | 6 Days to Air: The Making of South Park | Self | |
| Movie | 2022 | South Park the Streaming Wars | Various Characters (voice) | |
| Movie | 2007 | Electric Apricot | Tom the Taper | |
| Movie | 2023 | South Park: Joining the Panderverse | Various Characters (voice) | |
| Movie | 2022 | South Park the Streaming Wars Part 2 | Various Characters (voice) | |
| Movie | 1998 | Chef Aid: Behind The Menu | Chef Aid Host / Kenny / Kenny's Dad (voices) (archive recording) | |
| Movie | 2009 | Direct Your Own Damn Movie! | Self | |
| Movie | 2022 | South Park: The 25th Anniversary Concert | Self | |
| Movie | 1995 | Your Studio and You | Man Toasting Drinks at MCA Outdoors Bar | |
| Movie | 2023 | South Park (Not Suitable for Children) | Various Characters (voice) | |
| Movie | 2002 | Run Ronnie Run | Self | |
| Movie | 2002 | Bowling for Columbine | Self | |
| Movie | 2005 | Team America: Building the World | Self | |
| Movie | 1996 | South Park: The Unaired Pilot | Kyle Broflovski / Kenny McCormmick / Pip Pirrup | |
| Movie | 2003 | The Book Of Orgazmo | Self | |
| Movie | 2003 | Shocked | | |
| Movie | 1999 | Goin' Down to South Park | Self | |
| Movie | 2024 | ¡Casa Bonita Mi Amor! | Self | |
| Movie | 2014 | 'Tallica Parking Lot | Kyle Broflovski / Kenny McCormick (voice) | |
| Movie | 2024 | South Park: The End of Obesity | Kyle Broflovski / Kenny McCormick / Butters Stotch / Gerald Broflovski (voice) | |
| Movie | 2002 | Bowling for Columbine | self | |
| Movie | 2017 | Night of Too Many Stars: America Unites for Autism Programs | Self | |
| Movie | 2007 | Christmas Time in South Park | Kyle Broflovski / Kenny McCormick / Gerald Broflovski (voice) | |
| Movie | 2010 | The Simpsons 20th Anniversary Special - In 3D! On Ice! | Self | |
| Movie | 2008 | Monty Python Conquers America | Self | |
| Movie | 2010 | Rush: Beyond the Lighted Stage | Self | |
| Movie | 1995 | Time Warped | | |
| Movie | 1998 | Monty Python: Live at Aspen | Self (uncredited) | |
| Movie | 1996 | For Goodness Sake II | | |
| Movie | 2020 | Sassy Justice | The Dialysis King | |
| TV Show | 1980 | Nightline | | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 3 |
| TV Show | 1996 | The Daily Show | Self | 1 |
| TV Show | 1997 | South Park | Kyle Broflovski / Kenny McCormick (voice) | 331 |
| TV Show | 1992 | The Tonight Show with Jay Leno | | 1 |
| TV Show | 1993 | Late Night with Conan O'Brien | Self - Guest | 1 |
| TV Show | 1956 | Tony Awards | Self - Winner | 1 |
| TV Show | 2015 | The Weekly with Charlie Pickering | Self | 1 |
