| Movie | 2004 | Team America: World Police | Gary Johnston / Joe / Kim Jong Il / Hans Blix / Carson / Matt Damon / Drunk in Bar / Tim Robbins / Sean Penn / Michael Moore / Helen Hunt / Susan Sarandon (voice) | |
| Movie | 2008 | The Masterpiece That Almost Wasn't | Self | |
| Movie | 1998 | Orgazmo | Joe Young / Orgazmo | |
| Movie | 1999 | South Park: Bigger, Longer & Uncut | Stan Marsh / Eric Cartman / Gregory / Satan / Mr. Garrison / Mr. Hat / Phillip Niles Argyle / Randy Marsh / Clyde Donovan / Tom - News Reporter / Midget In A Bikini / Canadian Ambassador / Bombardiers / Mr. Mackey / Army General / Ned Gerblanski / Christophe - Ze Mole (or The Mole) / Big Gay Al (singing) / Adolf Hitler / Additional Voices (voice) | |
| Movie | 2021 | South Park: Post COVID | Various Characters (voice) | |
| Movie | 1996 | Cannibal! The Musical | Alferd Packer | |
| Movie | 1989 | Man on Mars | Murphy | |
| Movie | 2004 | Tales from the Crapper | Steve Keen (as Juan Schwartz) | |
| Movie | 1999 | Terror Firmer | Hermaphrodite (uncredited) | |
| Movie | 1998 | BASEketball | Joe Cooper | |
| Movie | 1989 | First Date | Narrator | |
| Movie | 2005 | The Aristocrats | Cartman / Stan (voice) | |
| Movie | 2021 | South Park: Post COVID: The Return of COVID | Various Characters (voice) | |
| Movie | 2008 | South Park: Imaginationland | Various Characters (voice) | |
| Movie | 1992 | The Spirit of Christmas: Jesus vs. Frosty | Boy 1 / Santa Claus / Frosty (voice) | |
| Movie | 1995 | The Spirit of Christmas: Jesus vs. Santa | Eric Cartman / Stan Marsh / Santa (voice) | |
| Movie | 2011 | 6 Days to Air: The Making of South Park | Self | |
| Movie | 1999 | Revenge of the Roadkill Rabbit | Father Rabbit | |
| Movie | 2022 | South Park the Streaming Wars | Various Characters (voice) | |
| Movie | 2023 | South Park: Joining the Panderverse | Various Characters (voice) | |
| Movie | 2022 | South Park the Streaming Wars Part 2 | Various Characters (voice) | |
| Movie | 1998 | Chef Aid: Behind The Menu | Judge Moses / Mr. Mackey (voices) (archive recording) | |
| Movie | 2009 | Direct Your Own Damn Movie! | Self | |
| Movie | 2022 | South Park: The 25th Anniversary Concert | Self | |
| Movie | 1995 | Your Studio and You | Narrator (voice) / Man Walking Out Office / Man Toasting at Bar | |
| Movie | 2023 | South Park (Not Suitable for Children) | Various Characters (voice) | |
| Movie | 2002 | Run Ronnie Run | Self | |
| Movie | 2005 | Team America: Building the World | Self | |
| Movie | 1996 | South Park: The Unaired Pilot | Eric Cartman / Stan Marsh / Mr. Garrison / Mr. Hat | |
| Movie | 2003 | The Book Of Orgazmo | Self | |
| Movie | 2003 | Shocked | | |
| Movie | 1999 | Goin' Down to South Park | Self | |
| Movie | 2024 | ¡Casa Bonita Mi Amor! | Self | |
| Movie | 2014 | 'Tallica Parking Lot | Eric Cartman / Stan Marsh (voice) | |
| Movie | 2004 | The Thick Brown Line | Self | |
| Movie | 2024 | South Park: The End of Obesity | Stan Marsh / Eric Cartman (voice) | |
| Movie | 2014 | A LEGO Brickumentary | Self | |
| Movie | 2017 | Despicable Me 3 | Balthazar Bratt (voice) | |
| Movie | 2005 | Make Your Own Damn Movie! | Himself | |
| Movie | 2002 | Bowling for Columbine | Self | |
| Movie | 2007 | Christmas Time in South Park | Stan Marsh / Eric Cartman /Mr. Garrison /Mr. Mackey / Mr. Hankey / Satan / Adolf Hitler (voice) | |
| Movie | 2010 | The Simpsons 20th Anniversary Special - In 3D! On Ice! | Self | |
| Movie | 2008 | Monty Python Conquers America | Self | |
| Movie | 1995 | Time Warped | | |
| Movie | 1996 | For Goodness Sake II | | |
| Movie | 2020 | Sassy Justice | Al Gore | |
| Movie | 2024 | Despicable Me 4 | Balthazar Bratt (voice) (uncredited) | |
| TV Show | 1980 | Nightline | | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 3 |
| TV Show | 1996 | The Daily Show | Self | 1 |
| TV Show | 1997 | South Park | Eric Cartman / Stan Marsh (voice) | 331 |
| TV Show | 1992 | The Tonight Show with Jay Leno | | 1 |
| TV Show | 1993 | Late Night with Conan O'Brien | Self - Guest | 1 |
| TV Show | 2005 | I Love the '90s: Part Deux | | 10 |
| TV Show | 1999 | The Three Friends and Jerry | | 45 |
| TV Show | 1990 | Hull High | | 8 |
| TV Show | 2003 | VH1 Goes Inside | | 1 |
| TV Show | 1956 | Tony Awards | Self - Winner | 1 |
| TV Show | 2006 | America's Game: The Super Bowl Champions | Narrator (voice) | 1 |
| TV Show | 2015 | The Weekly with Charlie Pickering | Self | 1 |
| TV Show | 2018 | The Shivering Truth | (voice) | 2 |
| TV Show | 2017 | The Nineties | Self (archive footage) | 1 |
