| Movie | 1979 | Star Trek: The Motion Picture | Lt. Cmdr. Hikaru Sulu | |
| Movie | 1982 | Star Trek II: The Wrath of Khan | Cmdr. Hikaru Sulu | |
| Movie | 1984 | Star Trek III: The Search for Spock | Cmdr. Hikaru Sulu | |
| Movie | 1986 | Star Trek IV: The Voyage Home | Sulu | |
| Movie | 1989 | Star Trek V: The Final Frontier | Cmdr. Hikaru Sulu | |
| Movie | 1991 | Star Trek VI: The Undiscovered Country | Captain Hikaru Sulu | |
| Movie | 1998 | Mulan | First Ancestor (voice) | |
| Movie | 1968 | The Green Berets | Captain Nim | |
| Movie | 2004 | Mulan II | First Ancestor (voice) | |
| Movie | 2002 | New World Order | Radio Free World (voice) | |
| Movie | 2023 | The Keepers of the 5 Kingdoms | AO the Wise (voice) | |
| Movie | 2012 | Art of Submission | Krang | |
| Movie | 1963 | PT 109 | Helmsman on Japanese Destroyer (uncredited) | |
| Movie | 2006 | A.I. Assault | Major Lane | |
| Movie | 1960 | Hell to Eternity | George Une | |
| Movie | 1997 | Trekkies | Self | |
| Movie | 1966 | Walk Don't Run | Police Captain | |
| Movie | 2009 | Scooby-Doo! and the Samurai Sword | Old Man Samurai (voice) | |
| Movie | 1960 | Ice Palace | Wang | |
| Movie | 2004 | The Eavesdropper | Dr. Hsieh | |
| Movie | 2003 | Roddenberry on Patrol | Narrator | |
| Movie | 2011 | These Amazing Shadows | Self | |
| Movie | 1996 | Oblivion 2: Backlash | Doc Valentine | |
| Movie | 2008 | Ninja Cheerleaders | Hiroshi | |
| Movie | 1990 | Blood Oath | Vice-Admiral Baron Takahashi | |
| Movie | 1993 | The Curse of the Dragon | Narrator (voice) | |
| Movie | 1971 | Josie's Castle | Ken Tanaka | |
| Movie | 1998 | Bug Buster | Dr. Hiro Fujimoto | |
| Movie | 1989 | Return from the River Kwai | Lieutenant Tanaka | |
| Movie | 2011 | Larry Crowne | Dr. Matsutani | |
| Movie | 2020 | Who’s on Top? | | |
| Movie | 2024 | To the Journey: Looking Back at Star Trek: Voyager | Self | |
| Movie | 2012 | Strange Frame | Tamadamsa (voice) | |
| Movie | 2003 | DC 9/11: Time of Crisis | Norman Mineta | |
| Movie | 2013 | Free Birds | S.T.E.V.E. (voice) | |
| Movie | 2009 | Toyo's Camera | Self | |
| Movie | 2009 | You Don't Know Jack: The Jack Soo Story | Self | |
| Movie | 1993 | Live by the Fist | Uncle Coronado | |
| Movie | 2014 | To Be Takei | Self | |
| Movie | 2022 | Soul of a Nation Presents: Together As One: Celebrating Asian American, Native Hawaiian and Pacific Islander Heritage | Self - Host | |
| Movie | 2023 | One Fighting Irishman: Wayne M. Collins and the Tule Lake Segregation Center | Narrator | |
| Movie | N/A | Holograms All the Way Down | Hikaru Sulu | |
| Movie | 2013 | The Missing Scarf | Narrator | |
| Movie | 1995 | Kissinger and Nixon | Le Duc Tho | |
| Movie | 1963 | King Kong vs. Godzilla | Osamu Sakurai (voice) (uncredited) | |
| Movie | 2013 | Axel: The Biggest Little Hero | Elder (voice) | |
| Movie | 1986 | Who's Who | | |
| Movie | 2014 | Eat With Me | George | |
| Movie | 1965 | Red Line 7000 | Kato | |
| Movie | 1966 | An American Dream | Attorney Ord Long | |
| Movie | 2008 | The Great Buck Howard | George Takei | |
| Movie | 1959 | Never So Few | Soldier in Hospital | |
| Movie | 1970 | Which Way to the Front? | Yamashita | |
| Movie | 2012 | Space Milkshake | Gary (voice) | |
| Movie | 2009 | Bring Back... Star Trek | Self | |
| Movie | 2006 | Comedy Central Roast of William Shatner | Self - Roaster | |
| Movie | 2017 | Yamasong: March of the Hollows | Elder Masook (voice) | |
| Movie | 2019 | Cool Cat's Crazy Dream | Dream World George | |
| Movie | 2015 | Entourage | George Takei | |
| Movie | 2015 | Roddenberry's Trek | himself | |
| Movie | 1999 | Who Gets the House? | Elliott | |
| Movie | 1997 | The Best Bad Thing | Mr. Yamanaka | |
| Movie | 2015 | Message From Hiroshima | Narrator | |
| Movie | 2021 | Boulevard! A Hollywood Story | Self (archive footage) | |
| Movie | 2015 | Do I Sound Gay? | Self | |
| Movie | 1996 | The Making of Star Trek Deep Space Nine Trials And Tribble-ations | Self | |
| Movie | 2016 | Kubo and the Two Strings | Hosato (voice) | |
| Movie | 1995 | William Shatner's Star Trek Memories | Self | |
| Movie | 2016 | For the Love of Spock | Self | |
| Movie | 2005 | How William Shatner Changed The World | Self | |
| Movie | 2015 | Tab Hunter Confidential | Self | |
| Movie | 1975 | The Star Trek Dream | Self | |
| Movie | 2022 | Paws of Fury: The Legend of Hank | Ohga (voice) | |
| Movie | 2014 | Ava & Lala | | |
| Movie | 2012 | 8 | William Tam | |
| Movie | 1994 | William Shatner: Captain's Log | Self | |
| Movie | 2011 | Dark Vengeance | Tanaka | |
| Movie | 2016 | Allegiance | Sam Kimura / Ojii-Chan | |
| Movie | 1993 | Moving Memories | | |
| Movie | 1994 | Oblivion | Doc Valentine | |
| Movie | 1994 | Star Trek: A Captain's Log | Himself | |
| Movie | 1999 | Batman Beyond: The Movie | Mr. Fixx (voice) | |
| Movie | 2004 | Kiss 'N' Tell: Romance in the 23rd Century | | |
| Movie | 2004 | Birth of a Timeless Legacy | | |
| Movie | 2007 | Star Trek: Beyond the Final Frontier | Self | |
| Movie | 2017 | And Then They Came for Us | himself | |
| Movie | 1991 | Star Trek: 25th Anniversary Special | Self | |
| Movie | 2006 | 40 Years of Star Trek | Self | |
| Movie | 1959 | Gigantis, the Fire Monster | Ikeda / Osaka SDF Dispatcher (voice) (uncredited) | |
| Movie | 1975 | The Year of the Dragon | Fred Eng | |
| Movie | 2025 | The Gettysburg Address | Self | |
| Movie | 2012 | Backyard Blockbusters | Sulu (archive footage) | |
| Movie | 1967 | The Big Mouth | Diamond Jeweler (uncredited) | |
| Movie | 2008 | You Don't Mess with the Zohan | George Takei | |
| Movie | 1988 | The Star Trek Saga: From One Generation to the Next | Self | |
| Movie | 2016 | Star Trek: Inside the Roddenberry Vault | Self | |
| Movie | 2020 | Aliens Stole My Body | Phil the Plant (voice) | |
| Movie | 2009 | Annul Victory | Self | |
| Movie | 2022 | Yorktown: A Time to Heal | Lt. Cmdr. Hikaru Sulu | |
| Movie | 2020 | The Soul of America | Self | |
| Movie | 1977 | Have I Got a Christmas for You | Doctor | |
| Movie | 2021 | Woman in Motion | Self | |
| Movie | 2008 | Futurama: Bender's Game | George Takei (voice) | |
| Movie | 2009 | The Pool Boys | Maitre D (Joon) | |
| Movie | 2007 | Finishing the Game: The Search for a New Bruce Lee | Man in Black (Voice) | |
| Movie | 1997 | The Magic Pearl | Ha Ping (voice) | |
| Movie | 2025 | Coroner to the Stars | Self | |
| Movie | 2010 | The Untold Story of Ralph Carr and the Japanese: The Fate of 3 Japanese-Americans and the Internment | Himself | |
| Movie | 1957 | Rodan! The Flying Monster! | Dr. Kyuichiro Kashiwagi / Izeki / male honeymooner (voice) | |
| Movie | 2025 | Beam Me Up, Sulu | Self | |
| Movie | 2025 | Reclaim the Flag | Self | |
| TV Show | 1995 | In the House | | 1 |
| TV Show | 2000 | Son of the Beach | | 1 |
| TV Show | 1999 | Batman Beyond | Mr. Fixx (voice) | 2 |
| TV Show | 2005 | Freddie | Martin | 1 |
| TV Show | 1989 | The Simpsons | Akira Kurosawa (voice) | 1 |
| TV Show | 1962 | The Gallant Men | | 1 |
| TV Show | 1994 | Spider-Man | Wong (voice) | 1 |
| TV Show | 2000 | Jackie Chan Adventures | High Mystic (voice) | 1 |
| TV Show | 1966 | Star Trek | Sulu | 79 |
| TV Show | 2007 | The Big Bang Theory | Self | 1 |
| TV Show | 1999 | Futurama | George Takei's Head (voice) | 4 |
| TV Show | 1993 | Kung Fu: The Legend Continues | Colonel Ong | 1 |
| TV Show | 1996 | Space Cases | | 1 |
| TV Show | 2006 | Heroes | Kaito Nakamura | 13 |
| TV Show | 1995 | Star Trek: Voyager | Captain Sulu | 1 |
| TV Show | 1984 | Miami Vice | | 1 |
| TV Show | 1996 | Early Edition | Mr. Lee | 1 |
| TV Show | 2001 | According to Jim | George Takei (voice) | 1 |
| TV Show | 1968 | Hawaii Five-O | Nathaniel Blake | 1 |
| TV Show | 1974 | Chico and the Man | | 1 |
| TV Show | 1973 | Star Trek | Hikaru Sulu (voice) | 22 |
| TV Show | 2000 | Malcolm in the Middle | George Takei | 1 |
| TV Show | 1998 | V.I.P. | KOP's Voice / Self | 1 |
| TV Show | 1999 | The Early Show | Self | 1 |
| TV Show | 1985 | MacGyver | Dr. Shen Wei | 1 |
| TV Show | 1957 | Perry Mason | Toma Sakai | 1 |
| TV Show | 2008 | Star Wars: The Clone Wars | Lok Durd (voice) | 1 |
| TV Show | 1959 | Hawaiian Eye | | 4 |
| TV Show | 1966 | Mission: Impossible | Roger Lee | 1 |
| TV Show | 1965 | Mister Roberts | | 1 |
| TV Show | 2008 | Secret Talents of the Stars | | 2 |
| TV Show | 1960 | The Islanders | Yung | 1 |
| TV Show | 2001 | Scrubs | George Takei | 1 |
| TV Show | 1995 | Brotherly Love | George Takei | 1 |
| TV Show | 1998 | Will & Grace | George Takei | 1 |
| TV Show | 2007 | El Tigre: The Adventures of Manny Rivera | | 1 |
| TV Show | 1951 | Hallmark Hall of Fame | Doctor | 1 |
| TV Show | 1959 | The Twilight Zone | Arthur Takamori / Taro | 1 |
| TV Show | 2005 | Bring Back... | Self | 1 |
| TV Show | 1967 | Ironside | | 1 |
| TV Show | 1996 | Muppets Tonight | Self | 1 |
| TV Show | 1966 | Felony Squad | | 1 |
| TV Show | 1978 | Vega$ | | 1 |
| TV Show | 1996 | Once a Thief | | 1 |
| TV Show | 2007 | Chowder | Foie Gras (voice) | 1 |
| TV Show | 1963 | Bob Hope Presents the Chrysler Theatre | | 1 |
| TV Show | 2003 | Alienated | | 1 |
| TV Show | 2000 | Baby Blues | | 1 |
| TV Show | 2010 | Adventure Time | Ricardio (voice) | 2 |
| TV Show | 1991 | Lightning Force | General Seng | 2 |
| TV Show | 2009 | Party Down | George Takei | 1 |
| TV Show | 1993 | Diagnosis: Murder | Man In Black | 1 |
| TV Show | 2012 | The New Normal | Sam | 1 |
| TV Show | 1993 | GMTV | Self | 1 |
| TV Show | 1960 | My Three Sons | Won Tsun | 1 |
| TV Show | 2008 | All Star Mr & Mrs | | 1 |
| TV Show | 2009 | Live from Studio Five | Self | 1 |
| TV Show | 2011 | Supah Ninjas | Hattori 'Hologramps' Fukanaga | 39 |
| TV Show | 2010 | Scooby-Doo! Mystery Incorporated | Mr. Wang / White Wizard (voice) | 1 |
| TV Show | 2009 | Community | George Takei (voice) | 1 |
| TV Show | 2023 | BLUE EYE SAMURAI | Seki (voice) | 8 |
| TV Show | 2001 | The Chronicle | Mr. Shen | 1 |
| TV Show | 1996 | The Daily Show | Self | 2 |
| TV Show | 2006 | Psych | George Takei | 1 |
| TV Show | 2021 | Marvel's Hit-Monkey | Shinji (voice) | 10 |
| TV Show | 2002 | Kim Possible | Sensei (voice) | 6 |
| TV Show | 2010 | Hawaii Five-0 | Uncle Choi | 2 |
| TV Show | 2023 | Gremlins: Secrets of the Mogwai | Noggin (voice) | 9 |
| TV Show | 2014 | Late Night with Seth Meyers | Self | 1 |
| TV Show | 2015 | StarTalk with Neil deGrasse Tyson | Self | 1 |
| TV Show | 2016 | Elena of Avalor | King Toshi (voice) | 1 |
| TV Show | 2010 | Pound Puppies | Mr. Julius (voice) | 1 |
| TV Show | 2010 | Pound Puppies | Mr. Julius / Monsieur Mitch (voice) | 1 |
| TV Show | 2008 | The Suite Life on Deck | Rome Tipton | 1 |
| TV Show | 2014 | Penn Zero: Part-Time Hero | Sylvester Kobayashi (voice) | 2 |
| TV Show | 1974 | The Six Million Dollar Man | Chin-Ling | 1 |
| TV Show | 2010 | Fish Hooks | Bird / Robot (voice) | 1 |
| TV Show | 2010 | Fish Hooks | Mr. Bird (voice) | 1 |
| TV Show | 2010 | Fish Hooks | Mr. K (voice) | 1 |
| TV Show | 1969 | The Courtship of Eddie's Father | Mr. Sato | 1 |
| TV Show | 2014 | The 7D | Dr. Sweet Tooth (voice) | 1 |
| TV Show | 1996 | Hey Arnold! | Phoebe's Father (voice) | 1 |
| TV Show | 2021 | Jellystone! | SoSo (voice) | 1 |
| TV Show | 2007 | Rick & Steve: The Happiest Gay Couple in All the World | Mayor Screwsum / Police Chief (voice) | 1 |
| TV Show | 2015 | Fresh Off the Boat | Bernard | 2 |
| TV Show | 2000 | The Brak Show | | 1 |
| TV Show | 1997 | The View | Self - Guest | 1 |
| TV Show | 2006 | The Howard Stern Interview | Self | 1 |
| TV Show | 2022 | ONI: Thunder God's Tale | Mr. Tengu (voice) | 4 |
| TV Show | 2007 | Phineas and Ferb | Positive Re-enforcement Machine (voice) | 1 |
| TV Show | 1985 | Doctor Who's Who's Who | Sulu | 1 |
| TV Show | 1995 | Happily Ever After: Fairy Tales for Every Child | Keiji (voice) | 1 |
| TV Show | 1995 | Happily Ever After: Fairy Tales for Every Child | Change / Peddler (voice) | 1 |
| TV Show | 2002 | After They Were Famous | Self | 1 |
| TV Show | 2022 | The Shuttlepod Show | Self | 1 |
| TV Show | 2004 | Star Trek: New Voyages | Hikaru Sulu | 1 |
| TV Show | 2010 | Transformers: Prime | Alpha Trion (voice) | 2 |
| TV Show | 2009 | Archer | Mr. Moto (voice) | 2 |
| TV Show | 2021 | Resident Alien | The Gray (voice) | 3 |
| TV Show | 2011 | The Problem Solverz | | 1 |
| TV Show | 2018 | The Terror | Nobuhiro Yamato / Yamato-san | 10 |
| TV Show | 2024 | Avatar the Last Airbender | Koh (voice) | 1 |
| TV Show | 2010 | Regular Show | Daisuke (voice) | 1 |
| TV Show | 2020 | Star Trek: Lower Decks | Hikaru Sulu (voice) | 1 |
| TV Show | 2010 | Lost Girl | Engelram | 1 |
| TV Show | 1980 | Beyond Westworld | Doctor Marcus | 1 |
| TV Show | 2000 | Grosse Pointe | Japanese Ad Executive (uncredited) | 1 |
| TV Show | 2002 | I'm a Celebrity...Get Me Out of Here! | Self | 17 |
| TV Show | 1996 | 3rd Rock from the Sun | George Takei | 1 |
| TV Show | 1982 | Matt Houston | Sam Shima | 1 |
| TV Show | 2015 | The Late Show with Stephen Colbert | Self | 1 |
| TV Show | 2007 | The Graham Norton Show | Self | 1 |
| TV Show | 2014 | BoJack Horseman | Audiobook Narrator (voice) | 1 |
| TV Show | 2019 | True Terror with George Takei | Self - Host | 6 |
| TV Show | 2003 | Comedy Central Roasts | Self | 1 |
| TV Show | 2009 | Watch What Happens Live with Andy Cohen | Self - Guest | 2 |
| TV Show | 2013 | Through the Keyhole | Self | 1 |
| TV Show | 2020 | Love Monster | Elder Panda (voice) | 80 |
| TV Show | 2005 | American Dad! | George Takei (voice) | 1 |
| TV Show | 2007 | Transformers: Animated | Yoketron (voice) | 1 |
| TV Show | 2020 | Visible: Out on Television | Self | 5 |
| TV Show | 2003 | Real Time with Bill Maher | Self | 1 |
| TV Show | 2021 | Call Me Kat | Self | 1 |
| TV Show | 2007 | Cory in the House | Ronald | 1 |
| TV Show | 2018 | Star Trek: Short Treks | Hikaru Sulu (voice) (archive footage) | 1 |
| TV Show | 2019 | Scooby-Doo and Guess Who? | George Takei (voice) | 1 |
| TV Show | 1984 | Murder, She Wrote | Bert Tanaka | 1 |
| TV Show | 2005 | Avatar: The Last Airbender | Warden (voice) | 1 |
| TV Show | 2023 | Star Trek: very Short Treks | Sulu (voice) | 2 |
| TV Show | 2001 | Samurai Jack | Warrior #4 (voice) | 1 |
| TV Show | 2011 | Bubble Guppies | Major Bummer (voice) | 1 |
| TV Show | 2011 | Bubble Guppies | Master Rakunuki (voice) | 1 |
| TV Show | 2007 | Thank God You're Here | Self | 1 |
| TV Show | 1989 | The Simpsons | Wink - The Game Show Host (voice) | 1 |
| TV Show | 1989 | The Simpsons | Waiter (voice) | 1 |
| TV Show | 1989 | The Simpsons | Sushi Chef (voice) | 1 |
| TV Show | 1989 | The Simpsons | George Takei (voice) | 1 |
| TV Show | 1964 | Voyage to the Bottom of the Sea | Cheng | 1 |
| TV Show | 2010 | Hot in Cleveland | Reverend Matsuda | 1 |
| TV Show | 2005 | Robot Chicken | Godzilla vs. Jason Narrator / Yakuza (voice) | 1 |
| TV Show | 2005 | Robot Chicken | Hikaru Sulu / Purple Crayon Narrator (voice) | 1 |
| TV Show | 2012 | Marvel's Ultimate Spider-Man | Master of K'un L'un (voice) | 1 |
