| Movie | 1998 | Appointment With The Wise Old Dog | Self | |
| Movie | 2000 | Appalachian Journey Live In Concert | Self | |
| Movie | 2012 | The Goat Rodeo Sessions Live | Self | |
| Movie | 1998 | Bach Cello Suite #1: The Music Garden | himself | |
| Movie | 1998 | Bach Cello Suite #2: The Sound of the Carceri | himself | |
| Movie | 2018 | Won't You Be My Neighbor? | Self - Musician and Fred's Friend | |
| Movie | 1997 | Falling Down Stairs | Self | |
| Movie | 1997 | Sarabande | Himself | |
| Movie | 2014 | Blue Gold: American Jeans | | |
| Movie | 2022 | Glass Onion: A Knives Out Mystery | Yo-Yo Ma | |
| Movie | 2003 | Beethoven - Choral Fantasy and Triple Concerto for Violin, Cello & Piano | Self (cellist) | |
| Movie | 2004 | Yo-Yo Ma Plays Ennio Morricone | Himself | |
| Movie | 1997 | Struggle for Hope | | |
| Movie | 2016 | The Music of Strangers: Yo-Yo Ma and the Silk Road Ensemble | Self | |
| Movie | 2024 | Music by John Williams | Self - Cellist | |
| Movie | 2009 | Chris Botti in Boston | Self | |
| Movie | 2017 | The Words That Built America | Self - Reader: Declaration of Independence | |
| Movie | 2018 | Mister Rogers: It's You I Like | Self | |
| Movie | 1997 | The Best of Sessions at West 54th: Vol. 1 | Self | |
| Movie | 2018 | Leonard Bernstein Centennial Celebration at Tanglewood | Self - Cellist | |
| Movie | 1985 | Ozawa | | |
| Movie | 1995 | Beethoven: Triple Concerto And Choral Fantasy | Self | |
| Movie | 2015 | Yo Yo Ma: The Bach Project– Six Cello Suites | | |
| Movie | 1993 | Dvorak in Prague: A Celebration | Self | |
| Movie | 2024 | Notre-Dame de Paris : La Réouverture - La Grande Soirée | Self | |
| Movie | 2025 | Half Moon | | |
| Movie | 1997 | Six Gestures | Self | |
| Movie | 2025 | Jacqueline du Pré: Genius and Tragedy | Narrator (voice) | |
| Movie | 2012 | How to Grow a Band | | |
| TV Show | 1992 | The Tonight Show with Jay Leno | | 1 |
| TV Show | 2005 | The Colbert Report | | 1 |
| TV Show | 2015 | The Late Show with Stephen Colbert | Self | 2 |
| TV Show | 2019 | Desus & Mero | Self | 1 |
| TV Show | 1999 | The West Wing | Yo-Yo Ma | 1 |
| TV Show | 2020 | Deeper Look from New York | Self | 2 |
| TV Show | 2014 | Last Week Tonight with John Oliver | Voice Over (voice) | 1 |
| TV Show | 1993 | Frasier | Tom (voice) | 1 |
| TV Show | 1996 | Arthur | Yo-Yo Ma (voice) | 2 |
| TV Show | 1962 | The Tonight Show Starring Johnny Carson | Self | 1 |
| TV Show | 1998 | Yo-Yo Ma: Inspired by Bach | | 6 |
| TV Show | 1972 | Le Grand Échiquier | Self - Main Guest | 1 |
| TV Show | 1989 | The Simpsons | Yo-Yo Ma (voice) | 1 |
| TV Show | 2018 | Firing Line with Margaret Hoover | | 1 |
