| Movie | 2007 | Meet the Robinsons | Franny (voice) | |
| Movie | 2002 | The Third Wheel | Sally (uncredited) | |
| Movie | 2005 | Kim Possible Movie: So the Drama | Shego (voice) | |
| Movie | 2008 | Superhero Movie | Julia Riker | |
| Movie | 2005 | Barry Dingle | Ethel Shivers | |
| Movie | 2000 | Buzz Lightyear of Star Command: The Adventure Begins | Mira Nova (voice) | |
| Movie | 2003 | Kim Possible: A Sitch In Time | Shego (voice) | |
| Movie | 2010 | Firebreather | Dr. Pytel (voice) | |
| Movie | 2005 | Sesame Street: All-Star Alphabet | Self - The Letter A | |
| Movie | 2022 | Teen Titans Go! & DC Super Hero Girls: Mayhem in the Multiverse | Supergirl (voice) | |
| Movie | 2012 | Let It Shine | Lyla | |
| Movie | 2012 | The Penguins of Madagascar: Operation Blowhole | Marlene (voice) | |
| Movie | 2001 | The Way She Moves | Beth | |
| Movie | 2009 | Black Dynamite | Patricia Nixon | |
| Movie | 2014 | Eat With Me | Maureen | |
| Movie | 2016 | Heaven's Floor | Karen | |
| Movie | 2014 | All-Stars | Jill Levitan | |
| Movie | 2002 | My Sister's Keeper | Alissa | |
| Movie | 2010 | The Penguins of Madagascar - Operation: Get Ducky | Marlene | |
| Movie | 2014 | Jackhammer | Crazy Lucy | |
| Movie | 2009 | 17 Again | Naomi | |
| Movie | 2016 | Pee-wee's Big Holiday | Shelly | |
| Movie | 1999 | Say You’ll Be Mine | | |
| Movie | 2014 | Lennon or McCartney | Self | |
| Movie | 2000 | Bar Hopping | Mara | |
| Movie | 2019 | Surprise Me! | Ellen | |
| Movie | 2018 | The Late Batsby | Kara Zor-El/Supergirl (voice) | |
| Movie | 2018 | I'll Be Next Door for Christmas | Ms. James | |
| Movie | 2006 | The Ant Bully | Ant #9 (voice) | |
| Movie | 2019 | Mushroom and the Forest of the World | Forest Witch | |
| Movie | 2020 | DIVOS! | Candy | |
| Movie | 2005 | Guess Who | Liz Klein | |
| Movie | 2014 | The Penguins of Madagascar: Operation Special Delivery | Marlene (voice) | |
| Movie | 2002 | A Baby Blues Christmas Special | Bizzy (voice) | |
| Movie | 2019 | DC Super Hero Girls: Sweet Justice | Supergirl (voice) | |
| Movie | 2009 | Zac Efron's Pool Party | Randi | |
| Movie | 2021 | It Takes Three | Laura Berger | |
| Movie | 2010 | The Penguins of Madagascar: Happy King Julien Day | Marlene | |
| TV Show | 2000 | Titus | Carol | 1 |
| TV Show | 1995 | The Drew Carey Show | Diane Pulaski | 1 |
| TV Show | 2002 | Less than Perfect | Deirdre Bishop | 2 |
| TV Show | 2005 | Numb3rs | Nancy Hackett | 1 |
| TV Show | 2000 | CSI: Crime Scene Investigation | Nancy Twicker | 1 |
| TV Show | 2005 | American Dad! | Janice (voice) | 1 |
| TV Show | 1999 | Family Guy | Muriel Goldman (voice) | 4 |
| TV Show | 2003 | Miss Match | Rachel | 1 |
| TV Show | 2002 | Monk | Janet Novak | 1 |
| TV Show | 2001 | According to Jim | Alicia | 1 |
| TV Show | 2002 | Clone High | Joan of Arc (voice) | 13 |
| TV Show | 2002 | Kim Possible | | 14 |
| TV Show | 2002 | Kim Possible | Shego (voice) | 14 |
| TV Show | 2000 | Buzz Lightyear of Star Command | Princess Mira Nova (voice) | 62 |
| TV Show | 1999 | Law & Order: Special Victims Unit | Jen Caulder | 1 |
| TV Show | 1993 | Diagnosis: Murder | Nurse | 1 |
| TV Show | 1998 | The King of Queens | Marilyn | 1 |
| TV Show | 1994 | Party of Five | | 1 |
| TV Show | 1994 | Models Inc. | | 1 |
| TV Show | 2002 | Kim Possible | Shego / Computer Voice (voice) | 2 |
| TV Show | 2007 | Raines | Carolyn Crumley | 7 |
| TV Show | 2001 | Scrubs | Jill Tracy | 6 |
| TV Show | 1997 | Pepper Ann | Tundra Woman (voice) | 1 |
| TV Show | 1995 | MADtv | Various | 157 |
| TV Show | 2004 | Boston Legal | Joan Rubin | 1 |
| TV Show | 2008 | Rita Rocks | Rita Clemens | 40 |
| TV Show | 2005 | Hot Properties | Chloe Reid | 13 |
| TV Show | 2005 | The Late Late Show with Craig Ferguson | Self | 1 |
| TV Show | 2007 | Slacker Cats | | 12 |
| TV Show | 1995 | Maybe This Time | | 1 |
| TV Show | 2008 | The Secret Saturdays | Drew Saturday (voice) | 49 |
| TV Show | 2000 | Baby Blues | (voice) | 8 |
| TV Show | 2017 | Will & Grace | Ruth | 1 |
| TV Show | 2023 | Clone High | Joan of Arc (voice) | 20 |
| TV Show | 2008 | The Wendy Williams Show | | 1 |
| TV Show | 2014 | Last Week Tonight with John Oliver | Pam | 1 |
| TV Show | 2009 | The Middle | Vicki | 1 |
| TV Show | 2010 | $#*! My Dad Says | Bonnie Goodson | 18 |
| TV Show | 2017 | Girlboss | Teresa | 2 |
| TV Show | 2014 | black-ish | Janine | 28 |
| TV Show | 2018 | Good Girls | Teacher | 1 |
| TV Show | 1998 | The King of Queens | Holly Shumpert | 98 |
| TV Show | 2018 | The Neighborhood | Alexis | 1 |
| TV Show | 1999 | Family Guy | Mrs. Abbott (voice) | 1 |
| TV Show | 1999 | Family Guy | Mega Hardware Customer (voice) | 1 |
| TV Show | 1999 | Family Guy | Stewie's Customer (voice) / Y2K Crown (voice) | 1 |
| TV Show | 1999 | Family Guy | Girl in a Scavenger Hunt / Cashier (voice) | 1 |
| TV Show | 1999 | Family Guy | Angelica / Cheerleader / Sorority Girl (voice) | 1 |
| TV Show | 1999 | Family Guy | Alexis Radcliffe (voice) | 1 |
| TV Show | 1999 | Family Guy | Bride / Candi / Mary (voice) | 1 |
| TV Show | 1999 | Family Guy | Mrs. Goldman (voice) | 1 |
| TV Show | 1999 | Family Guy | Tina (voice) | 1 |
| TV Show | 1999 | Family Guy | Shelly / Muriel Goldman (voice) | 1 |
| TV Show | 1999 | Family Guy | (voice) | 7 |
| TV Show | 1999 | Family Guy | Drunk Chick (voice) | 1 |
| TV Show | 1999 | Family Guy | Joan the Maid (voice) | 1 |
| TV Show | 1999 | Family Guy | Nurse at Sperm Bank (voice) | 1 |
| TV Show | 1999 | Family Guy | Boxer (voice) | 1 |
| TV Show | 1999 | Family Guy | Taco Lover (voice) | 1 |
| TV Show | 2023 | American Born Chinese | Robin | 1 |
| TV Show | 2013 | Mom | Leanne | 2 |
| TV Show | 2002 | Kim Possible | Shego / Miss Go (voice) | 1 |
| TV Show | 1999 | Family Guy | Meredith (voice) | 1 |
| TV Show | 2002 | Clone High | Marie Curie (voice) | 3 |
| TV Show | 2013 | Amethyst: Princess of Gemworld | Jalapeño Vendor (voice) | 1 |
| TV Show | 2022 | Murderville | Rebecca Hendricks | 1 |
| TV Show | 2012 | The Mindy Project | Dr. Weitzel | 1 |
| TV Show | 2014 | BoJack Horseman | Fan Girl (voice) | 1 |
| TV Show | 2014 | Celebrity Name Game | Self | 2 |
| TV Show | 2017 | Disjointed | Maria | 20 |
| TV Show | 2013 | Teen Titans Go! | Supergirl (voice) | 5 |
| TV Show | 2001 | Stanley | Farmer Julie (voice) | 1 |
| TV Show | 2021 | Name That Tune | Self - Contestant | 1 |
| TV Show | 1995 | MADtv | Mindy Tikvah | 1 |
| TV Show | 2013 | Wendell & Vinnie | Wilma Bassett | 20 |
| TV Show | 1995 | MADtv | Meg Ryan | 1 |
| TV Show | 1995 | MADtv | Lida | 1 |
| TV Show | 1995 | MADtv | Self | 2 |
| TV Show | 2007 | Head Case | Self | 2 |
| TV Show | 2016 | Hollywood Medium with Tyler Henry | Self - Guest | 1 |
| TV Show | 2003 | Celebrity Poker Showdown | Self | 2 |
| TV Show | 2019 | High School Musical: The Musical: The Series | Carol Salazar-Roberts | 3 |
| TV Show | 2010 | Worst Cooks in America | | 2 |
| TV Show | 2005 | Bones | Joanne DeMarco | 1 |
| TV Show | 2005 | The Suite Life of Zack & Cody | Miss Klotz | 1 |
| TV Show | 1991 | Rugrats | Debbie / Customer (voice) | 1 |
| TV Show | 2008 | The Penguins of Madagascar | Marlene (voice) | 149 |
| TV Show | 2008 | True Jackson, VP | Kreuftlva | 1 |
| TV Show | 2004 | Brandy & Mr. Whiskers | Gerri (voice) | 1 |
| TV Show | 2019 | Harley Quinn | Mrs. Cobblepot / Benjamin (voice) | 1 |
| TV Show | 2019 | DC Super Hero Girls | Kara Danvers / Supergirl (voice) | 78 |
| TV Show | 2005 | Grey's Anatomy | JJ | 1 |
| TV Show | 2019 | All Rise | Bea Greer | 1 |
| TV Show | 2018 | 25 Words or Less | | 1 |
| TV Show | 1999 | Family Guy | Amber (voice) | 1 |
| TV Show | 2014 | BoJack Horseman | (voice) | 1 |
| TV Show | 2014 | BoJack Horseman | Party Goer (voice) | 1 |
| TV Show | 2009 | Cougar Town | Lynn Mettler | 7 |
| TV Show | 2008 | Leverage | Heather Moscone | 1 |
| TV Show | 2022 | Pictionary | Self | 1 |
| TV Show | 2009 | RuPaul's Drag Race | Self - Guest Judge | 1 |
| TV Show | 2021 | The Sex Lives of College Girls | Carol Finkle | 6 |
| TV Show | 1997 | Fired Up | Debbie | 2 |
| TV Show | 2003 | Lilo & Stitch: The Series | Shego (voice) | 1 |
| TV Show | 1991 | Herman's Head | Young Woman | 1 |
| TV Show | 2011 | The Exes | Melanie | 1 |
| TV Show | 2011 | Whitney | Alicia | 1 |
| TV Show | 2019 | Bob Hearts Abishola | Lorraine | 3 |
| TV Show | 2000 | Daddio | Miss Lang | 1 |
| TV Show | 2007 | Thank God You're Here | Self | 1 |
| TV Show | 2013 | Devious Maids | Molly | 1 |
| TV Show | 2018 | Liverspots and Astronots | Big Man | 21 |
| TV Show | 2019 | Christy's Kitchen Throwback | | 1 |
| TV Show | 1996 | Suddenly Susan | Claire | 1 |
| TV Show | 2012 | Super Best Friends Forever | Supergirl (voice) | 4 |
