| Movie | 1995 | Toy Story | Rex (voice) | |
| Movie | 1999 | Toy Story 2 | Rex (voice) | |
| Movie | 1979 | Manhattan | Jeremiah | |
| Movie | 2010 | Toy Story 3 | Rex (voice) | |
| Movie | 1995 | Canadian Bacon | Canadian Prime Minister Clark MacDonald | |
| Movie | 1987 | The Princess Bride | Vizzini | |
| Movie | 2001 | The Curse of the Jade Scorpion | George Bond | |
| Movie | 2007 | Southland Tales | Baron Von Westphalen | |
| Movie | 2007 | Happily N'Ever After | Munk (voice) | |
| Movie | 1983 | Deal of the Century | Harold DeVoto | |
| Movie | 2009 | Capitalism: A Love Story | Self | |
| Movie | 1981 | Cheaper to Keep Her | Mugger | |
| Movie | 1984 | The Hotel New Hampshire | Freud | |
| Movie | 1980 | Atlantic City | Waiter | |
| Movie | 1994 | Mrs. Parker and the Vicious Circle | Horatio Byrd | |
| Movie | 1987 | Radio Days | Masked Avenger | |
| Movie | 2008 | Kit Kittredge: An American Girl | Mr. Gibson | |
| Movie | 1981 | My Dinner with Andre | Wallace Shawn | |
| Movie | 2001 | Monsters, Inc. | Rex (voice) (uncredited) | |
| Movie | 1994 | Vanya on 42nd Street | Vanya | |
| Movie | 2008 | Scooby-Doo! and the Goblin King | Mr. Gibbles (voice) | |
| Movie | 1995 | Clueless | Mr. Wendell Hall | |
| Movie | 2005 | Chicken Little | Principal Fetchit (voice) | |
| Movie | 1999 | My Favorite Martian | Coleye | |
| Movie | 2004 | Melinda and Melinda | Sy | |
| Movie | 1992 | Mom and Dad Save the World | Sibor, Semage's Beau | |
| Movie | 1987 | Prick Up Your Ears | John Lahr | |
| Movie | 1984 | Micki & Maude | Dr. Elliot Fibel | |
| Movie | 2009 | Jack and the Beanstalk | Booker / Broker / Lancealot Squarejaw | |
| Movie | 1985 | Head Office | Mike Hoover | |
| Movie | 2009 | The Windmill Movie | Self | |
| Movie | 1988 | The Moderns | Oiseau | |
| Movie | 1981 | Strong Medicine | Birthday Party Guest (uncredited) | |
| Movie | 2011 | The Speed of Thought | Sandy | |
| Movie | 2006 | Tom and Jerry: Shiver Me Whiskers | Barnacle Paul (voice) | |
| Movie | 2003 | Monte Walsh | Colonel Wilson | |
| Movie | 1997 | Critical Care | Furnaceman | |
| Movie | 2001 | The Prime Gig | Gene | |
| Movie | 2008 | USIDent TV: Surveilling the Southland | Self | |
| Movie | 1995 | A Goofy Movie | Principal Mazur (voice) | |
| Movie | 1987 | The Bedroom Window | Henderson's Attorney | |
| Movie | 1983 | Strange Invaders | Earl | |
| Movie | 1989 | She's Out of Control | Dr. Fishbinder | |
| Movie | 1996 | All Dogs Go to Heaven 2 | Labrador MC (voice) | |
| Movie | 1983 | Lovesick | Otto Jaffe | |
| Movie | 1992 | The Double 0 Kid | Cashpot | |
| Movie | 2012 | Vamps | Dr. Van Helsing | |
| Movie | 1995 | The Wife | Cosmo | |
| Movie | 1993 | The Magic Bubble | Doctor/Therapist | |
| Movie | 1987 | Nice Girls Don't Explode | Ellen | |
| Movie | 1984 | Crackers | Turtle | |
| Movie | 2011 | Hawaiian Vacation | Rex (voice) | |
| Movie | 1999 | The Diary of the Hurdy-Gurdy Man | | |
| Movie | 2012 | A Late Quartet | Gideon Rosen | |
| Movie | 1985 | Heaven Help Us | Father Abruzzi | |
| Movie | 2013 | Admission | Clarence | |
| Movie | 2004 | Karroll's Christmas | | |
| Movie | 2014 | The Double | Mr. Papadopoulos | |
| Movie | 2012 | Partysaurus Rex | Rex (voice) | |
| Movie | 1997 | Just Write | Arthur Blake | |
| Movie | 2013 | Andre Gregory: Before and After Dinner | Self | |
| Movie | 2010 | Furry Vengeance | Dr. Christian Burr (uncredited) | |
| Movie | 1998 | Noah | | |
| Movie | 1983 | The First Time | Jules Goldfarb | |
| Movie | 2013 | Toy Story of Terror! | Rex (Voice) | |
| Movie | 2007 | The Pixar Story | Rex (voice) (archive footage) | |
| Movie | 2003 | The Haunted Mansion | Ezra | |
| Movie | 2014 | A Master Builder | Halvard Solness | |
| Movie | 2009 | André Gregory and Wallace Shawn | | |
| Movie | 1979 | All That Jazz | Assistant Insurance Man | |
| Movie | 1995 | Driving Mr. Pink | Boss Man (voice) | |
| Movie | 2003 | Love Thy Neighbor | Clinic Doctor | |
| Movie | 1980 | Simon | Eric Van Dongen | |
| Movie | 2014 | Toy Story That Time Forgot | Rex (voice) | |
| Movie | 1991 | Shadows and Fog | Simon Carr | |
| Movie | 2014 | Christmas at Cartwright's | Harry | |
| Movie | 1989 | We're No Angels | Translator | |
| Movie | 1996 | House Arrest | Victor Finley | |
| Movie | 2016 | Maggie's Plan | Kliegler | |
| Movie | 1997 | Vegas Vacation | Marty | |
| Movie | 2015 | Robo-Dog | Mr. Willis | |
| Movie | 1979 | Starting Over | Workshop Member | |
| Movie | 2004 | Teacher's Pet | Principal Crosby Strickler (voice) | |
| Movie | 2002 | Personal Velocity | Mr. Gelb | |
| Movie | 2004 | The Incredibles | Gilbert Huph (voice) | |
| Movie | 2011 | Small Fry | Rex (voice) | |
| Movie | 2015 | Club Penguin Halloween Panic! | Gary | |
| Movie | 2003 | Duplex | Herman | |
| Movie | 1982 | A Little Sex | Oliver | |
| Movie | 1984 | How to Be a Perfect Person in Just Three Days | Professor Silverfish | |
| Movie | 1983 | Saigon: Year of the Cat | Frank Judd | |
| Movie | 2010 | Cats & Dogs: The Revenge of Kitty Galore | Calico (voice) | |
| Movie | 1989 | Scenes from the Class Struggle in Beverly Hills | Howard | |
| Movie | 2017 | Animal Crackers | Mr. Woodley (voice) | |
| Movie | 1995 | Just Like Dad | Stan Spiegel | |
| Movie | 1992 | Nickel & Dime | Everett Willits | |
| Movie | 2015 | Club Penguin Monster Beach Party | Gary the Gadget Guy (voice) | |
| Movie | 1984 | The Bostonians | Mr. Pardon | |
| Movie | 2006 | Air Buddies | Billy (voice) | |
| Movie | 2017 | Cop and a Half: New Recruit | Principal Miller | |
| Movie | 1996 | The Story Behind 'Toy Story' | Self | |
| Movie | 2000 | Buzz Lightyear of Star Command: The Adventure Begins | Rex (voice) | |
| Movie | 2017 | The Only Living Boy in New York | David | |
| Movie | 1984 | My Dinner with Louis | Interviewer | |
| Movie | 2018 | Book Club | Dr. Derek | |
| Movie | 2017 | Another Kind of Wedding | Albert | |
| Movie | 1993 | The Meteor Man | Mr. Little | |
| Movie | 2016 | Starring Austin Pendleton | Self | |
| Movie | 2001 | As You Wish: The Story of 'The Princess Bride' | Self | |
| Movie | 2018 | What We Left Behind: Looking Back at Star Trek: Deep Space Nine | Self | |
| Movie | 2019 | Toy Story 4 | Rex (voice) | |
| Movie | 2020 | Rifkin’s Festival | Mort Rifkin | |
| Movie | 2020 | Timmy Failure: Mistakes Were Made | Mr. Crocus | |
| Movie | 2019 | Marriage Story | Frank | |
| Movie | 2006 | Howard Zinn: Voices of a People's History of the United States | Self | |
| Movie | 2019 | Forky Asks a Question: What Is Time? | Rex (voice) | |
| Movie | 2009 | Jack and the Beanstalk | Broker / Booker / Lancelot Squarejaw | |
| Movie | 2007 | I Could Never Be Your Woman | Math Teacher (uncredited) | |
| Movie | 2020 | A Virtual Princess Bride Reunion | Vizzini | |
| Movie | 2014 | The Fog of Courage | Eustace Bagge | |
| Movie | 1998 | The Jungle Book: Mowgli's Story | Tarzan Chimp (voice) | |
| Movie | 1995 | Napoleon | Echidna (voice) | |
| Movie | 2021 | Waiting for Godot | Lucky | |
| Movie | 2021 | The Addams Family 2 | Mr. Mustela (voice) | |
| Movie | 2007 | Strange Culture | Self | |
| Movie | 2015 | Toy Story at 20: To Infinity and Beyond | Self (archive footage) | |
| Movie | 1993 | The Cemetery Club | Larry | |
| Movie | 2002 | Mr. St. Nick | Mimir | |
| Movie | 2014 | Phineas and Ferb Save Summer | Saul (voice) | |
| Movie | 2017 | Drawing Home | | |
| Movie | N/A | The Man Who Changed the World | | |
| Movie | 2009 | Pixar Short Films | Rex (voice) | |
| Movie | 2014 | Don Peyote | Dr. Fieldman | |
| TV Show | 1999 | Family Guy | Bertram (voice) | 3 |
| TV Show | 2004 | Desperate Housewives | Lonny Moon | 1 |
| TV Show | 1997 | Ally McBeal | Mr. Dune | 1 |
| TV Show | 1984 | The Cosby Show | Jeffrey Engels | 5 |
| TV Show | 1993 | The Nanny | Charles Haste | 1 |
| TV Show | 2001 | Crossing Jordan | Howard Stiles | 8 |
| TV Show | 2000 | Teacher's Pet | Principal Strickler (voice) | 47 |
| TV Show | 2005 | Fat Actress | Dr. Von Oy | 1 |
| TV Show | 2004 | The L Word | William Halsey | 4 |
| TV Show | 2001 | Law & Order: Criminal Intent | Film Professor | 1 |
| TV Show | 1997 | Stargate SG-1 | Arlos | 1 |
| TV Show | 1993 | Homicide: Life on the Street | | 1 |
| TV Show | 2015 | Mr. Robot | Mr. Williams | 1 |
| TV Show | 1993 | The Pink Panther | Boss Man (voice) | 69 |
| TV Show | 1997 | The Wonderful World of Disney | | 1 |
| TV Show | 2016 | Search Party | William Badpastor | 2 |
| TV Show | 2019 | Amphibia | Humphrey (voice) | 1 |
| TV Show | 2007 | Gossip Girl | Cyrus Rose | 11 |
| TV Show | 1999 | Law & Order: Special Victims Unit | Roy Batters | 1 |
| TV Show | 1996 | Toy Story Treats | Rex (Voice) | 55 |
| TV Show | 2009 | The Good Wife | Charles Lester | 3 |
| TV Show | 2021 | Gossip Girl | Cyrus Rose | 1 |
| TV Show | 2014 | BoJack Horseman | Wallace Shawn (voice) | 1 |
| TV Show | 2006 | Eureka | Warren Hughes | 2 |
| TV Show | 1978 | Taxi | Arnie Ross | 1 |
| TV Show | 2010 | Fish Hooks | Rat King (voice) | 1 |
| TV Show | 2014 | The 7D | Not-So-Magic-Mirror (voice) | 1 |
| TV Show | 1978 | Taxi | Arnie | 1 |
| TV Show | 2010 | Buzz Lightyear Mission Logs | Rex (voice) | 3 |
| TV Show | 2001 | Blonde | I.E. Shinn | 2 |
| TV Show | 2007 | Phineas and Ferb | Saul (voice) | 1 |
| TV Show | 2019 | Evil | Father Francis Ignatius | 10 |
| TV Show | 2017 | The Good Fight | Charles Lester | 5 |
| TV Show | 1993 | Star Trek: Deep Space Nine | Zek | 7 |
| TV Show | 2018 | Big City Greens | Jyle (voice) | 1 |
| TV Show | 2018 | Summer Camp Island | Morris Mole (voice) | 1 |
| TV Show | 2018 | Summer Camp Island | Barry (voice) | 1 |
| TV Show | 2018 | Summer Camp Island | Pete (voice) | 1 |
| TV Show | 2010 | Regular Show | Evil Brain (voice) | 1 |
| TV Show | 2015 | Life in Pieces | Samuel | 1 |
| TV Show | 2008 | Life on Mars | The Sorcerer | 1 |
| TV Show | 1999 | Law & Order: Special Victims Unit | Benjamin Edelman | 1 |
| TV Show | 2017 | Young Sheldon | John Sturgis | 53 |
| TV Show | 1998 | The Lionhearts | (voice) | 4 |
| TV Show | 1989 | The Simpsons | Wallace the Hernia (voice) | 1 |
| TV Show | 1998 | Sex and the City | Martin Gable | 1 |
| TV Show | 2014 | Mozart in the Jungle | Winslow Elliott | 6 |
| TV Show | 2014 | The Mysteries of Laura | Kenneth Walters | 1 |
| TV Show | 1997 | King of the Hill | Philip Ny (voice) | 1 |
| TV Show | 2006 | Eureka | Dr. Warren Hughes | 1 |
| TV Show | 2014 | The Night Shift | Mr. Neville | 1 |
| TV Show | 2016 | The Stinky & Dirty Show | Tall (voice) | 5 |
| TV Show | 2023 | Krapopolis | John Fate (voice) | 1 |
| TV Show | 2017 | The Marvelous Mrs. Maisel | Herb Smith | 1 |
