| Movie | N/A | Girls Trip 2 | Dina | |
| Movie | 2022 | Easter Sunday | Vanessa Morgan | |
| Movie | 2023 | Back on the Strip | Verna | |
| Movie | 2012 | Snoop Dogg Presents The Bad Girls of Comedy | Self | |
| Movie | 2021 | Tiffany Haddish Does Shark Week | Self | |
| Movie | 2020 | Comedy Confessions | Self | |
| Movie | 2022 | Boosters LA | Debra | |
| Movie | 2023 | Albert Brooks: Defending My Life | Self | |
| Movie | 2023 | A Very Demi Holiday Special | Self | |
| Movie | 2023 | TMZ's Merry Elfin' Christmas | Self | |
| Movie | 2024 | Bad Boys: Ride or Die | Tabitha | |
| Movie | 2014 | Jenny McCarthy's Dirty Sexy Funny | Herself | |
| Movie | 2017 | Dying Laughing | Self | |
| Movie | N/A | The Deputy | Amanda Jackson | |
| Movie | 2016 | Keanu | Hi-C | |
| Movie | 2017 | Girls Trip | Dina | |
| Movie | N/A | Untitled Kestrin Pantera Indie Project | | |
| Movie | 2017 | Mad Families | Keko | |
| Movie | 2017 | Tiffany Haddish: She Ready! From the Hood to Hollywood! | Herself | |
| Movie | 2009 | Janky Promoters | Michelle | |
| Movie | 2008 | Meet the Spartans | Urban Girl | |
| Movie | 2012 | What My Husband Doesn't Know | Falana | |
| Movie | 2008 | Racing for Time | Denise | |
| Movie | 2013 | A Christmas Wedding | Aurora | |
| Movie | 2011 | Driving by Braille | Drum Major | |
| Movie | 2005 | The Urban Demographic | Janice Green | |
| Movie | 2014 | School Dance | Trina | |
| Movie | 2014 | Wishes | Jeanie | |
| Movie | 2017 | Def Comedy Jam 25 | Self | |
| Movie | 2019 | The Kitchen | Ruby O'Carroll | |
| Movie | 2017 | DeRay Davis' Annual Funny & Famous Comedy Jam | | |
| Movie | 2017 | Great Performers: Horror Show | The Macabre Dancer | |
| Movie | 2018 | Night School | Carrie | |
| Movie | 2018 | Seth Rogen's Hilarity for Charity | Self | |
| Movie | 2019 | The Lego Movie 2: The Second Part | Queen Watevra Wa'Nabi (voice) | |
| Movie | 2018 | The Oath | Kai | |
| Movie | 2018 | Nobody's Fool | Tanya | |
| Movie | 2018 | Uncle Drew | Jess | |
| Movie | 2019 | The Secret Life of Pets 2 | Daisy (voice) | |
| Movie | 2020 | Like a Boss | Mia Carter | |
| Movie | 2018 | Forbidden | | |
| Movie | 2018 | All Between Us | Mishawn | |
| Movie | 2014 | Patterns of Attraction | Sandra Lewis | |
| Movie | 2019 | This Changes Everything | Self | |
| Movie | 2019 | Tiffany Haddish: Black Mitzvah | Herself | |
| Movie | 2018 | Emmet's Holiday Party: A LEGO Movie Short | Queen Watevra Wa’Nabi (voice) | |
| Movie | 2019 | I Am Richard Pryor | Self - Actress and Comedian | |
| Movie | 2019 | Camp! The Movie | Self | |
| Movie | 2019 | Still Laugh-In: The Stars Celebrate | Self | |
| Movie | 2021 | Bad Trip | Trina Malone | |
| Movie | 2014 | 4Play | Comedian | |
| Movie | N/A | Down Under Cover | | |
| Movie | 2019 | The Angry Birds Movie 2 | Debbie (voice) | |
| Movie | 2019 | Hello, Privilege. It's Me, Chelsea | Self | |
| Movie | 2019 | Between Two Ferns: The Movie | Tiffany Haddish | |
| Movie | 2019 | Live in Front of a Studio Audience: "All in the Family" and "Good Times" | Willona Woods | |
| Movie | 2021 | The Card Counter | La Linda | |
| Movie | 2017 | All Jokes Aside | Self | |
| Movie | 2020 | This Is Stand-Up | Self | |
| Movie | 2020 | Feeding America Comedy Festival | Self | |
| Movie | 2021 | Here Today | Emma Payge | |
| Movie | 2020 | Phineas and Ferb the Movie: Candace Against the Universe | The Sound Someone Makes When They Explode From The Waist Up (voice) | |
| Movie | 2020 | VOMO: Vote or Miss Out | Self | |
| Movie | N/A | Homecoming Queen | | |
| Movie | 2022 | The Unbearable Weight of Massive Talent | Vivian | |
| Movie | 2020 | The SpongeBob Movie: Sponge on the Run | Master of Ceremonies (voice) | |
| Movie | 2020 | In Search of the Sanderson Sisters: A Hocus Pocus Hulaween Takeover | Tiffany Haddish | |
| Movie | 2020 | Mariah Carey's Magical Christmas Special | Self | |
| Movie | 2022 | On the Count of Three | Natasha | |
| Movie | 2010 | Wax On, Fuck Off | Prostitute | |
| Movie | 2020 | Yearly Departed | Self | |
| Movie | 2023 | Landscape with Invisible Hand | Beth Campbell | |
| Movie | 2020 | The Broken Candle | Ella | |
| Movie | 2023 | Haunted Mansion | Harriet | |
| Movie | N/A | I.F. | | |
| Movie | N/A | Haunted Heist | | |
| Movie | 2017 | Moonlight | Phoebe | |
| Movie | 2018 | Taylor Swift: Reputation Stadium Tour | Self | |
| Movie | N/A | Toad | | |
| Movie | 2020 | Saving OurSelves: BET COVID-19 Relief Effort | Self | |
| TV Show | 2005 | My Name Is Earl | Robin | 1 |
| TV Show | 2005 | It's Always Sunny in Philadelphia | Stripper #3 | 1 |
| TV Show | 2022 | The Afterparty | Detective Danner | 18 |
| TV Show | 2015 | The Late Show with Stephen Colbert | Self | 5 |
| TV Show | 2008 | Reality Bites Back | | 8 |
| TV Show | 1997 | The View | Self - Guest | 1 |
| TV Show | 2021 | Friday Night Vibes | Self - Host | 21 |
| TV Show | 2009 | The Great Debate | | 6 |
| TV Show | 2009 | Secret Girlfriend | | 1 |
| TV Show | 2021 | Money, Explained | Self - Narrator | 1 |
| TV Show | 2011 | Brain Games | Self | 1 |
| TV Show | 2021 | The D'Amelio Show | Self (cameo) | 1 |
| TV Show | 2019 | Straight Up Steve Austin | Self | 1 |
| TV Show | 2011 | New Girl | Leslie | 1 |
| TV Show | 2014 | Tyler Perry's If Loving You Is Wrong | Jackie | 94 |
| TV Show | 2021 | The Freak Brothers | Kitty (voice) | 16 |
| TV Show | 2003 | The Ellen DeGeneres Show | Self | 6 |
| TV Show | 1987 | Kids' Choice Awards | Self - Presenter | 1 |
| TV Show | 2023 | Celebrity Prank Wars | Self | 1 |
| TV Show | 2020 | Punk'd | Self | 1 |
| TV Show | 2015 | The Late Late Show with James Corden | Self | 1 |
| TV Show | 2015 | The Carmichael Show | Nekeisha | 32 |
| TV Show | 1992 | MTV Movie & TV Awards | Self - Host | 1 |
| TV Show | 2022 | Phat Tuesdays: The Era of Hip Hop Comedy | Self | 3 |
| TV Show | 2017 | The High Court | Guest Bailiff | 1 |
| TV Show | 2016 | Legends of Chamberlain Heights | Cindy | 20 |
| TV Show | 1984 | MTV Video Music Awards | Self | 1 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self | 2 |
| TV Show | 2014 | Late Night with Seth Meyers | Self | 3 |
| TV Show | 1953 | The Oscars | Self | 1 |
| TV Show | 2022 | The Proud Family: Louder and Prouder | Ms. Hill (voice) | 1 |
| TV Show | 2020 | Celebrity IOU | Self | 1 |
| TV Show | 2020 | Home Movie: The Princess Bride | Princess Buttercup | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 3 |
| TV Show | 2022 | Dark Side of Comedy | Self | 1 |
| TV Show | 2017 | Face Value | | 12 |
| TV Show | 2018 | The Last O.G. | Shay | 30 |
| TV Show | 2019 | The Kelly Clarkson Show | | 1 |
| TV Show | 2014 | TripTank | Delsyia (voice) | 1 |
| TV Show | 2020 | Legendary | Self - Guest Judge | 1 |
| TV Show | 2009 | Watch What Happens Live with Andy Cohen | Self - Guest | 2 |
| TV Show | 2019 | Tuca & Bertie | Tuca (voice) | 30 |
| TV Show | 1975 | Saturday Night Live | Self - Host | 1 |
| TV Show | 2022 | Right to Offend: The Black Comedy Revolution | Self | 2 |
| TV Show | 2012 | Honest Trailers | Harriet (archive footage) | 1 |
| TV Show | 1997 | The View | Self | 1 |
| TV Show | 2011 | Bob's Burgers | Patricia (voice) | 1 |
| TV Show | 1969 | Sesame Street | Dr. Birdwhistle | 1 |
| TV Show | 2018 | My Next Guest Needs No Introduction with David Letterman | Self | 1 |
| TV Show | 2019 | Kids Say the Darndest Things | Self - Host | 20 |
| TV Show | 2019 | What Just Happened??! with Fred Savage | | 1 |
| TV Show | 2017 | Carpool Karaoke: The Series | Self | 1 |
| TV Show | 2022 | Sherri | Self - Guest | 1 |
| TV Show | 2019 | The Kelly Clarkson Show | Self | 1 |
| TV Show | 2020 | Self Made: Inspired by the Life of Madam C.J. Walker | Lelia | 4 |
| TV Show | 2018 | The Shop | Self | 1 |
| TV Show | 2003 | That's So Raven | Charlotte | 1 |
| TV Show | 2019 | Sherman's Showcase | Tiffany Haddish | 1 |
| TV Show | 2012 | Good Mythical Morning | Self | 1 |
| TV Show | 2013 | @midnight with Chris Hardwick | Self | 2 |
| TV Show | 2020 | Bookmarks: Celebrating Black Voices | | 1 |
| TV Show | 2018 | Double Dare | Self - Contestant | 2 |
| TV Show | 2015 | Close Up with The Hollywood Reporter | Self | 2 |
| TV Show | 2020 | Solar Opposites | Aisha (voice) | 23 |
| TV Show | 2012 | Russell Simmons Presents: The Ruckus | Self | 1 |
| TV Show | 2020 | Who Wants to Be a Millionaire | Self - Contestant | 1 |
| TV Show | 2018 | Lie Detector | Self | 1 |
| TV Show | 1999 | Mark Twain Prize | Self | 1 |
| TV Show | 2024 | Is It Cake? Holiday | Self - Guest Judge | 1 |
| TV Show | 2014 | Variety Studio: Actors on Actors | Self | 1 |
| TV Show | 2023 | Dr Phil LIVE! | Self | 1 |
| TV Show | 2025 | Hollywood Squares | Self | 6 |
| TV Show | 2025 | Number One on the Call Sheet | Self | 1 |
| TV Show | 2016 | The $100,000 Pyramid | Self | 1 |
| TV Show | 1974 | American Music Awards | Self - Presenter | 1 |
| TV Show | 2021 | Celebrity Wheel of Fortune | Self - Contestant | 1 |
| TV Show | 2018 | What the Fit | Self | 1 |
| TV Show | 2020 | Solar Opposites | Aisha / Jackie (voice) | 1 |
| TV Show | 2013 | Whose Line Is It Anyway? | Self - Special Guest | 1 |
