| Movie | 1988 | Married to the Mob | Homicide Detective | |
| Movie | 2021 | Sam Morril: Full Capacity | | |
| Movie | 2003 | Richard Pryor: I Ain't Dead Yet, #*%$#@!! | Self | |
| Movie | 2011 | Colin Quinn: Long Story Short | Himself | |
| Movie | 2010 | Grown Ups | Dickie Bailey | |
| Movie | 2002 | Comedian | Self | |
| Movie | 2013 | Grown Ups 2 | Dickie Bailey | |
| Movie | 2020 | Mike Cannon: Life Begins | Self | |
| Movie | 2003 | When Stand Up Stood Out | Self | |
| Movie | 2021 | Patrice O'Neal: Killing Is Easy | Self | |
| Movie | 1988 | Crocodile Dundee II | Onlooker at Mansion | |
| Movie | 2003 | Comedy Central Roast of Denis Leary | Self | |
| Movie | 2005 | Comedy Central Roast of Jeff Foxworthy | Self | |
| Movie | 2011 | Cheat | Delivery Boy | |
| Movie | 2015 | Trainwreck | Gordon Townsend | |
| Movie | 2015 | Colin Quinn: Unconstitutional | Himself | |
| Movie | 2024 | Colin Quinn: Our Time Is Up | Self | |
| Movie | 2003 | Crooked Lines | Customer | |
| Movie | 2019 | Drunk Parents | Ryan the Bum #2 | |
| Movie | 2004 | Comedy Anatomy Presents: The Jim Norton Roast | Self | |
| Movie | 2003 | The Patrice O'Neal Roast | Self | |
| Movie | 2008 | Harold | Reedy | |
| Movie | 2016 | Colin Quinn: The New York Story | Himself | |
| Movie | 2017 | Sandy Wexler | Kevin Connors | |
| Movie | 1998 | A Night at the Roxbury | Dooley | |
| Movie | 1993 | Who's the Man? | Frankie Flynn | |
| Movie | 2012 | That's My Boy | Strip Club DJ | |
| Movie | 1992 | Carol Leifer: Gaudy, Bawdy & Blue | Mulligan | |
| Movie | 1987 | 3 Men and a Baby | Gift Shop Clerk | |
| Movie | 2017 | Where Have You Gone, Lou DiMaggio? | Self | |
| Movie | 2018 | The Roast of Rich Vos | Self | |
| Movie | 2018 | Breslin and Hamill: Deadline Artists | Self | |
| Movie | 2019 | Colin Quinn: Red State, Blue State | Self | |
| Movie | 2017 | Oh, Rick! | Self | |
| Movie | 2020 | Hubie Halloween | Janitor | |
| Movie | 2006 | Home | | |
| Movie | 2020 | Feeding America Comedy Festival | Self | |
| Movie | 2011 | Give It Up for Greg Giraldo | Self | |
| Movie | 2003 | Windy City Heat | Self | |
| Movie | 2021 | Rehab Cabin | Mr. Granger | |
| Movie | 2020 | Colin Quinn & Friends: A Parking Lot Comedy Show | Self | |
| Movie | 2004 | Last Laugh '04 | Self | |
| Movie | 2024 | Colin Quinn: Stamps & Tea | Self | |
| Movie | 1992 | One Night Stand: Colin Quinn | Self | |
| Movie | N/A | Jesters and Fools | Self | |
| Movie | 2007 | Saturday Night Live in the '90s: Pop Culture Nation | Self | |
| TV Show | 1992 | The Ben Stiller Show | | 1 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 1 |
| TV Show | 2002 | Tough Crowd with Colin Quinn | | 57 |
| TV Show | 1997 | The View | Self | 2 |
| TV Show | 1992 | The Tonight Show with Jay Leno | | 1 |
| TV Show | 2015 | The Late Show with Stephen Colbert | Self | 1 |
| TV Show | 1993 | Late Night with Conan O'Brien | Self - Guest | 6 |
| TV Show | 1989 | One Night Stand | | 1 |
| TV Show | 2010 | The Marriage Ref | Self - Panelist | 1 |
| TV Show | 2002 | The Colin Quinn Show | | 3 |
| TV Show | 1975 | Saturday Night Live | Self - Various Characters | 85 |
| TV Show | 1996 | The Daily Show | Self | 6 |
| TV Show | 2014 | Late Night with Seth Meyers | Self | 7 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self | 4 |
| TV Show | 1975 | Saturday Night Live | Self - Cameo (uncredited) | 3 |
| TV Show | 2016 | Horace and Pete | Jimmy | 10 |
| TV Show | 2010 | The Green Room with Paul Provenza | Self | 1 |
| TV Show | 1997 | The Chris Rock Show | | 1 |
| TV Show | 1984 | MTV Video Music Awards | Self - Preshow Host | 1 |
| TV Show | 1994 | Space Ghost Coast to Coast | | 1 |
| TV Show | 2012 | Comedians in Cars Getting Coffee | Self | 1 |
| TV Show | 1987 | Remote Control | himself | 6 |
| TV Show | 2009 | Watch What Happens Live with Andy Cohen | Self - Guest | 1 |
| TV Show | 2016 | Match Game | Self - Panelist | 1 |
| TV Show | 2019 | Lights Out with David Spade | Self | 1 |
| TV Show | 2003 | Comedy Central Roasts | Self | 2 |
| TV Show | 1984 | The Cosby Show | Davey Herbeck | 1 |
| TV Show | 2015 | Thank You and Sorry | | 6 |
| TV Show | 2010 | Conan | Self | 2 |
| TV Show | 2014 | Last Week Tonight with John Oliver | Voice Over (voice) | 1 |
| TV Show | 2017 | Crashing | | 1 |
| TV Show | 2013 | Beat Bobby Flay | Self | 1 |
| TV Show | 1996 | Pulp Comics | Cop | 1 |
| TV Show | 2014 | Late Night with Seth Meyers | Self - Guest | 1 |
