| Movie | 2010 | Shrek Forever After | Shrek (voice) | |
| Movie | 2001 | Shrek | Shrek / Blind Mouse (voice) | |
| Movie | 2004 | Shrek 2 | Shrek (voice) | |
| Movie | 2007 | Shrek the Third | Shrek (voice) | |
| Movie | 2002 | Austin Powers in Goldmember | Austin Powers / Dr. Evil / Goldmember / Fat Bastard | |
| Movie | 1999 | Austin Powers: The Spy Who Shagged Me | Austin Powers / Dr. Evil / Fat Bastard | |
| Movie | 1997 | Austin Powers: International Man of Mystery | Austin Powers / Dr. Evil | |
| Movie | 2003 | The Cat in the Hat | The Cat | |
| Movie | 1998 | 54 | Steve Rubell | |
| Movie | 1993 | So I Married an Axe Murderer | Charlie MacKenzie / Stuart MacKenzie | |
| Movie | 2003 | View from the Top | John Witney | |
| Movie | 1992 | Wayne's World | Wayne Campbell | |
| Movie | 1993 | Wayne's World 2 | Wayne Campbell | |
| Movie | 2008 | The Love Guru | Guru Pitka | |
| Movie | 2003 | The Ghost of Lord Farquaad | Shrek (voice) | |
| Movie | 1987 | Meet Julie | | |
| Movie | 2012 | Oscar Etiquette | Sir Cecil Washington | |
| Movie | 2001 | Shrek in the Swamp Karaoke Dance Party | Shrek / Blind Mouse (voice) (singing voice) | |
| Movie | 2007 | Shrek the Halls | Shrek (voice) | |
| Movie | 1999 | Madonna: The Video Collection 93:99 | Austin Powers (segment "Beautiful Stranger") | |
| Movie | 2002 | Pete's Meteor | Pete | |
| Movie | 2027 | Shrek 5 | Shrek (voice) | |
| Movie | 2009 | Inglourious Basterds | General Ed Fenech | |
| Movie | 2010 | Scared Shrekless | Shrek (voice) | |
| Movie | 2010 | Donkey's Christmas Shrektacular | Shrek (voice) | |
| Movie | 2004 | Far Far Away Idol | Shrek (voice) | |
| Movie | 2005 | Shelter from the Storm: A Concert for the Gulf Coast | Self - Presenter | |
| Movie | 2022 | The Kids in the Hall: Comedy Punks | Self | |
| Movie | 2000 | The Beatles Revolution | Self | |
| Movie | 2012 | Everything or Nothing | Self | |
| Movie | 2010 | Shrek's Yule Log | Shrek (voice) | |
| Movie | 2013 | Nantucket Film Festival's 2nd Comedy Roundtable | Self | |
| Movie | 1998 | The Thin Pink Line | Tim Broderick | |
| Movie | 1999 | Canned Ham: The Dr. Evil Story | Dr. Evil / Austin Powers | |
| Movie | 1999 | Saturday Night Live: 25th Anniversary Special | Self | |
| Movie | 2013 | Supermensch: The Legend of Shep Gordon | Self | |
| Movie | 2004 | Nobody Knows Anything! | "Eye" Witness | |
| Movie | 1978 | The Making of a President | | |
| Movie | 2014 | Monty Python Live (Mostly) | Self | |
| Movie | 2004 | Barbra Streisand: The Concert - Live at the MGM Grand | Linda Richman - CBS Version | |
| Movie | 2003 | Saturday Night Live: The Best of Chris Farley | Various (archive footage) (uncredited) | |
| Movie | 1998 | Saturday Night Live: The Best of Mike Myers | Self (archive footage) | |
| Movie | 1998 | Saturday Night Live: The Best of Phil Hartman | Self / Various Characters | |
| Movie | 2004 | Britney Spears: Greatest Hits - My Prerogative | Self | |
| Movie | 2015 | Being Canadian | Self | |
| Movie | 2022 | 2022 Rock & Roll Hall of Fame Induction Ceremony | Self (archive footage) | |
| Movie | 2013 | Shrek Stories | Shrek (voice) | |
| Movie | 2015 | I Am Chris Farley | Self | |
| Movie | 1991 | Saturday Night Live: Halloween Special | Wayne Campbell | |
| Movie | 2018 | Terminal | Clinton / Mr Franklyn | |
| Movie | 1999 | Mystery, Alaska | Donnie Shulzhoffer | |
| Movie | 2014 | Monty Python: The Meaning of Live | Self | |
| Movie | 1989 | Saturday Night Live: 15th Anniversary | Self | |
| Movie | N/A | Del | Del Close | |
| Movie | 2018 | The King | Self | |
| Movie | 1989 | Elvis Stories | Cockney Man | |
| Movie | 2018 | Bohemian Rhapsody | Ray Foster | |
| Movie | 2001 | The Concert for New York City | Self | |
| Movie | 2001 | Creating a Fairy Tale World: The Making of Shrek | Self | |
| Movie | 1985 | John and Yoko: A Love Story | Delivery Boy | |
| Movie | 1998 | Saturday Night Live: A Tribute to Chris Farley | Self | |
| Movie | 1998 | Burt Bacharach: One Amazing Night | Self | |
| Movie | 2001 | America | A Tribute to Heroes | Self | |
| Movie | 2006 | Home | | |
| Movie | 2020 | Stronger Together, Tous Ensemble | Self | |
| Movie | 1997 | Austin Powers' Electric Psychedelic Pussycat Swingers Club | Austin Powers | |
| Movie | 2012 | Dreamworks Spooky Stories | Shrek (voice) | |
| Movie | 2002 | Dave Foley's The True Meaning of Christmas Specials | Self | |
| Movie | 2022 | Amsterdam | Paul Canterbury | |
| Movie | 2006 | Freddie Mercury: A Kind of Magic | Self | |
| Movie | 2021 | The Sparks Brothers | Self | |
| Movie | 2012 | Dreamworks: Holiday Classics | Shrek (voice) | |
| Movie | 2012 | Shrek's Thrilling Tales | Shrek (voice) | |
| Movie | 2025 | Ladies & Gentlemen... 50 Years of SNL Music | Self (archive footage) | |
| Movie | 1988 | 110 Lombard | Mike | |
| Movie | 2025 | You Had to Be There: How the Toronto Godspell Ignited the Comedy Revolution... | Self | |
| Movie | 2007 | Saturday Night Live in the '90s: Pop Culture Nation | Self | |
| Movie | 2005 | Saturday Night Live in the '80s: Lost and Found | Self | |
| Movie | 1999 | Behind the Scenes of 'Austin Powers: The Spy Who Shagged Me' | Self | |
| Movie | 1995 | Queen: Champions of the World | Self | |
| Movie | 2003 | Shrek 3-D | Shrek | |
| Movie | 2003 | The Osbourne Family Christmas Special | Self | |
| Movie | 2026 | Lorne | Self | |
| Movie | 2026 | Michael | Walter Yetnikoff | |
| TV Show | 1994 | Inside the Actors Studio | Self | 2 |
| TV Show | 1980 | Bizarre | Timmy Byner | 0 |
| TV Show | 2003 | Jimmy Kimmel Live! | Self | 1 |
| TV Show | 1975 | Saturday Night Live | Self - Various Characters | 141 |
| TV Show | 1996 | The Daily Show | Self | 1 |
| TV Show | 1952 | Today | Self | 1 |
| TV Show | 1999 | The Early Show | Self | 1 |
| TV Show | 1992 | The Tonight Show with Jay Leno | | 4 |
| TV Show | 2012 | Inside Comedy | Self | 1 |
| TV Show | 1993 | Late Night with Conan O'Brien | Self - Guest | 2 |
| TV Show | 2008 | DreamWorks Shrek's Swamp Stories | Shrek (voice) | 4 |
| TV Show | 2005 | Sit Down Comedy with David Steinberg | | 1 |
| TV Show | 1992 | MTV Movie & TV Awards | Self - Host | 2 |
| TV Show | 2005 | Iconoclasts | Self | 1 |
| TV Show | 2002 | V Graham Norton | Self | 1 |
| TV Show | 1953 | The Oscars | Self | 5 |
| TV Show | 1993 | GMTV | Self | 1 |
| TV Show | 1975 | Saturday Night Live | Self - Cameo (uncredited) | 10 |
| TV Show | 1975 | Saturday Night Live | Self - Host | 1 |
| TV Show | 2018 | The Alec Baldwin Show | Self | 1 |
| TV Show | 2014 | Late Night with Seth Meyers | Self | 2 |
| TV Show | 2017 | The Gong Show | Tommy Maitland - Host | 17 |
| TV Show | 2015 | The Late Show with Stephen Colbert | Self - Guest | 1 |
| TV Show | 1988 | LIVE with Kelly and Mark | Self - Guest | 5 |
| TV Show | 1979 | The Littlest Hobo | Tommy (as Michael Meyers) | 1 |
| TV Show | 2006 | Second City: First Family of Comedy | Self | 3 |
| TV Show | 1999 | Teen Choice Awards | Self | 1 |
| TV Show | 1996 | The Rosie O'Donnell Show | Self | 1 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self | 1 |
| TV Show | 2022 | The Pentaverate | Various Characters | 6 |
| TV Show | 2014 | The Tonight Show Starring Jimmy Fallon | Self - Guest | 2 |
| TV Show | 2014 | Last Week Tonight with John Oliver | Self | 1 |
| TV Show | 2020 | Reunited Apart | Self | 1 |
| TV Show | 2006 | When the Levees Broke: A Requiem in Four Acts | Self | 4 |
| TV Show | 1987 | Kids' Choice Awards | Host | 1 |
| TV Show | 2009 | Late Night with Jimmy Fallon | Self - Guest | 1 |
| TV Show | 2014 | Monty Python's Best Bits (Mostly) | Self | 1 |
| TV Show | 1975 | Saturday Night Live | Self / Linda Richman | 1 |
| TV Show | 2003 | DreamWorks 6 Spooky Stories Collection | Shrek (voice) | 2 |
| TV Show | 2005 | Dreamworks 5 Holiday Classics Collection | Shrek (voice) | 5 |
| TV Show | 2026 | Hockey Fanatics | Himself | 1 |