| Movie | 2004 | Shaun of the Dead | Ed | |
| Movie | 2007 | Hot Fuzz | PC Danny Butterman | |
| Movie | 2005 | Spider-Plant Man | Scientist | |
| Movie | 2021 | Monster Family 2 | Frank Wishbone (voice) | |
| Movie | 2004 | Danger! 50,000 Zombies | Nick Frost | |
| Movie | 2024 | Timestalker | George | |
| Movie | 2005 | Kinky Boots | Don | |
| Movie | 2011 | Paul | Clive Gollings | |
| Movie | 2011 | The Adventures of Tintin | Thomson (voice) | |
| Movie | 2007 | Suck My Geek! | Self | |
| Movie | 2009 | The Boat That Rocked | Dave | |
| Movie | 2012 | Ice Age: Continental Drift | Flynn (voice) | |
| Movie | 2012 | Snow White and the Huntsman | Nion | |
| Movie | 2011 | Attack the Block | Ron | |
| Movie | 2013 | The World's End | Andrew Knightley | |
| Movie | 2014 | Cuban Fury | Bruce | |
| Movie | 2014 | The Boxtrolls | Mr. Trout (voice) | |
| Movie | 2004 | Spaced: Skip to the End | Self | |
| Movie | 2013 | Completing the Golden Mile: The Making of The World's End | Himself / Andy Knightley | |
| Movie | 2007 | The Fuzzball Rally | Himself | |
| Movie | 2026 | Whistle | Mr. Craven | |
| Movie | 2014 | Phineas and Ferb: Night of the Living Pharmacists | Ed (voice) | |
| Movie | 2024 | Get Away | Richard | |
| Movie | 2015 | Unfinished Business | Bill Whilmsley | |
| Movie | 2023 | Right Here, Right Now | Self | |
| Movie | 2024 | How to Date Billy Walsh | William | |
| Movie | 2007 | Conclusive: We Made Hot Fuzz | Self | |
| Movie | 2024 | Krazy House | Bernie Christian | |
| Movie | 2014 | Doctor Who: Last Christmas | Santa Claus | |
| Movie | 2025 | How to Train Your Dragon | Gobber | |
| Movie | N/A | Sweet Dreams | Frasier | |
| Movie | 2016 | The Huntsman: Winter's War | Nion | |
| Movie | N/A | 152 Days | | |
| Movie | 2024 | Seize Them! | Bobik | |
| Movie | 2024 | Black Cab | Ian | |
| Movie | 2014 | Lennon or McCartney | Self | |
| Movie | 2008 | Wild Child | Mr. Christopher | |
| Movie | 2007 | Penelope | Max | |
| Movie | 2019 | Fighting with My Family | Patrick 'Rowdy Ricky' Knight | |
| Movie | 2017 | Monster Family | Frank Wishbone (voice) | |
| Movie | 2018 | Slaughterhouse Rulez | Woody Chapman | |
| Movie | 2018 | Tomb Raider | Alan (uncredited) | |
| Movie | 2011 | Scrat's Continental Crack-Up: Part 2 | Flynn (voice) | |
| Movie | 2018 | The Festival | Ricky | |
| Movie | 2019 | Horrible Histories: The Movie — Rotten Romans | Arghus | |
| Movie | 2001 | Forced Hilarity | | |
| Movie | 2011 | Star Wars Spoofs | Himself | |
| Movie | 2019 | StarDog and TurboCat | Buddy (voice) | |
| Movie | 2020 | Vert | Jeff | |
| Movie | 1996 | Jim's Gift | Wally | |
| Movie | 2021 | Trollhunters: Rise of the Titans | Stuart (voice) | |
| Movie | 2016 | Syrenia | Dr. Welles | |
| Movie | 2021 | Scooby-Doo! The Sword and the Scoob | Merlin (voice) | |
| Movie | 2014 | Doctor Who: Dark Water / Death in Heaven | Santa Claus | |
| Movie | 2021 | The Sparks Brothers | Ringo Starr (voice) | |
| Movie | 2007 | Grindhouse | Baby Eater (segment "Don't") (uncredited) | |
| Movie | 2021 | Extinct | Captain (voice) | |
| Movie | 2025 | Grow | Arlo | |
| Movie | 2025 | Soaring to Life: The Making of How to Train Your Dragon | Self | |
| Movie | N/A | Untitled Cornetto Movie | | |
| Movie | 2014 | Asterix: The Mansions of the Gods | Obelix (voice UK Dub) | |
| Movie | 2011 | Behind the Block | Self | |
| TV Show | 1999 | Spaced | Mike Watt | 14 |
| TV Show | 1995 | Soccer AM | Self | 1 |
| TV Show | 2001 | Friday Night with Jonathan Ross | Self - Guest | 1 |
| TV Show | 2020 | Staged | Nick | 1 |
| TV Show | 2005 | Man Stroke Woman | | 12 |
| TV Show | 2006 | Hyperdrive | Commander Michael Henderson | 12 |
| TV Show | 2002 | Danger! 50,000 Volts! | | 9 |
| TV Show | 2021 | The Nevers | Declan 'Beggar King' Orrun | 6 |
| TV Show | 2019 | Why Women Kill | Bertram Fillcot | 10 |
| TV Show | 2009 | Chris Moyles' Quiz Night | Self | 1 |
| TV Show | 1988 | Comic Relief | | 1 |
| TV Show | N/A | Danger! Incoming Attack! | | 16 |
| TV Show | 1995 | Sharman | Chris | 1 |
| TV Show | 2003 | Spine Chillers | | 1 |
| TV Show | 2010 | Money | John Self | 2 |
| TV Show | 2005 | Doctor Who | Santa Claus | 1 |
| TV Show | 1998 | Big Train | Construction Worker (uncredited) | 1 |
| TV Show | 2014 | Mr Drew's School for Boys | Narrator | 4 |
| TV Show | 2014 | Mr. Sloane | Jeremy Sloane | 6 |
| TV Show | 2004 | Green Wing | Just a Man | 1 |
| TV Show | 2015 | Galavant | Andre | 1 |
| TV Show | 2015 | Into the Badlands | Bajie | 26 |
| TV Show | 2002 | Look Around You | Stone-age Man | 1 |
| TV Show | 2017 | Sick Note | Dr Ian Glennis | 14 |
| TV Show | 2002 | Top Gear | Self - Star in a Reasonably-Priced Car | 1 |
| TV Show | 2023 | Scott Pilgrim Takes Off | Studio Security #2 (voice) | 2 |
| TV Show | 2014 | Late Night with Seth Meyers | Self | 1 |
| TV Show | 2018 | 3Below: Tales of Arcadia | Stuart (voice) | 26 |
| TV Show | 2020 | Truth Seekers | Gus Roberts | 8 |
| TV Show | 2007 | The Graham Norton Show | Self | 2 |
| TV Show | 2007 | Phineas and Ferb | Ed (voice) | 1 |
| TV Show | 2024 | Star Wars: Skeleton Crew | SM-33 (voice) | 8 |
| TV Show | 2000 | Black Books | Security System Man | 1 |
| TV Show | 2010 | Conan | Self | 1 |
| TV Show | 2013 | The Last Leg | Self | 1 |
| TV Show | 2005 | Dirty Tricks | Monkey (voice) | 1 |
| TV Show | 2002 | Look Around You | Hot Jon | 1 |
| TV Show | 2006 | The One Show | Self | 2 |
| TV Show | N/A | Harry Potter | Rubeus Hagrid | 1 |
| TV Show | 2013 | It's Kevin | Bongo Player | 1 |
| TV Show | 2025 | Transaction | Simon | 6 |
| TV Show | 2005 | Twisted Tales | Keith | 1 |