| Movie | 2007 | The Wonder of It All | himself | |
| Movie | 1976 | The Boy in the Plastic Bubble | Himself | |
| Movie | 2012 | James Cameron & Buzz Aldrin: Explorers - Von der Titanic bis zum Mond | | |
| Movie | 2008 | Fly Me to the Moon | Himself | |
| Movie | 2007 | In the Shadow of the Moon | Himself | |
| Movie | 2008 | When We Left Earth | Himself | |
| Movie | 2006 | Explorers: From The Titanic To The Moon | Self | |
| Movie | 2006 | Apollo 11: The Untold Story | Himself - Apollo 11 Astronaut | |
| Movie | 1972 | Moonwalk One | Self | |
| Movie | 2014 | Aliens on the Moon: The Truth Exposed | Self - Apollo 11 Astronaut | |
| Movie | 1969 | Footprints On The Moon | Himself | |
| Movie | 2000 | The Beatles Revolution | Self | |
| Movie | 2012 | First Man on the Moon | Himself | |
| Movie | 1990 | Fire, Ice & Dynamite | Buzz Aldrin | |
| Movie | 2015 | Doolittle's Raiders: A Final Toast | Self | |
| Movie | 2004 | Astronauts Gone Wild: An Investigation Into the Authenticity of the Moon Landings | Himself | |
| Movie | 2007 | The Pixar Story | Self (archive footage) | |
| Movie | 1976 | I, Tintin | Self (archive footage) | |
| Movie | 1995 | Doomed Mission: The True Story of Apollo 13 | Self | |
| Movie | 2012 | Apollo 11: First Steps On the Moon | Self | |
| Movie | 2024 | Hazardous Journey - The Apollo 11 Moon Landing | Self (archive footage) | |
| Movie | 1989 | For All Mankind | Self (archive footage) | |
| Movie | 2019 | Apollo: The Forgotten Films | Self (archive footage) | |
| Movie | 1996 | Apollo 11: First Steps on the Moon | Rev. Woodruff | |
| Movie | 2016 | Passage to Mars | Self | |
| Movie | 2016 | The University | Himself | |
| Movie | 2011 | Transformers: Dark of the Moon | Buzz Aldrin | |
| Movie | 2002 | Project Gemini: A Bold Leap Forward | Himself | |
| Movie | 2017 | Salute to Apollo: EAA AirVenture Oshkosh 2017 | | |
| Movie | 2019 | How the Moon Conquered Pop | Self (voice) | |
| Movie | 2019 | Apollo 11 | Self (archive footage) | |
| Movie | 2003 | The Truth Behind the Moon Landings | Self | |
| Movie | 1991 | Star Trek: 25th Anniversary Special | Self | |
| Movie | 2013 | Moonscape | Buzz Aldrin | |
| Movie | 2019 | Apollo: Missions to the Moon | Self - Lunar Module Pilot, Apollo 11 (archive footage) | |
| Movie | 2002 | Dark Side of the Moon | Self - Apollo 11 | |
| Movie | 1969 | The Eagle Has Landed: The Flight of Apollo 11 | Himself | |
| Movie | 1997 | Trekkies | Self | |
| Movie | 2019 | Als keiner schlafen wollte - Die Mondlandung | Self (archive footage) | |
| Movie | 1990 | The Other Side of the Moon | Self | |
| Movie | 2019 | Confessions from Space: Apollo | Self | |
| Movie | 2021 | Apollo 11: Quarantine | Himself | |
| Movie | 2019 | Moon Landing Live | Himself | |
| Movie | 2021 | kid 90 | Self (archive footage) | |
| Movie | 2016 | Generation Sputnik | Self - Astronaut (archive footage) | |
| Movie | 2019 | On Camera: Fifteen Apollo Astronauts and Their Experience of a Lifetime | | |
| Movie | 2008 | Wisdom | Self | |
| Movie | 2003 | Project Gemini: Bridge to the Moon | Self | |
| Movie | 1997 | The Making of ‘Moebius’ | Self (archive footage) | |
| Movie | 2025 | Sally | Self (archive footage) | |
| TV Show | 1989 | The Simpsons | Buzz Aldrin (voice) | 3 |
| TV Show | 2005 | Numb3rs | Self | 1 |
| TV Show | 1996 | E! True Hollywood Story | | 1 |
| TV Show | 1984 | Punky Brewster | Himself | 1 |
| TV Show | 2006 | 30 Rock | Buzz Aldrin | 1 |
| TV Show | 2005 | The Colbert Report | | 1 |
| TV Show | 2015 | StarTalk with Neil deGrasse Tyson | Self | 1 |
| TV Show | 2005 | Hell's Kitchen | Self - Restaurant Patron | 1 |
| TV Show | 2010 | Top Gear | | 1 |
| TV Show | 2005 | Dancing with the Stars | Self - Contestant | 5 |
| TV Show | 2007 | The Big Bang Theory | Self | 1 |
| TV Show | 1996 | The Rosie O'Donnell Show | Self | 1 |
| TV Show | 1994 | Space Ghost Coast to Coast | | 2 |
| TV Show | 2019 | Chasing the Moon | Self | 3 |
| TV Show | 2010 | America: The Story of Us | Self | 3 |
| TV Show | 1993 | Raw | | 2 |
| TV Show | 1995 | Les mercredis de l'histoire | Himself - Apollo 11 | 1 |
| TV Show | 2015 | Jorden runt på 6 steg | | 1 |
| TV Show | 1999 | Futurama | Buzz Aldrin (voice) | 1 |
| TV Show | 1998 | Style & Substance | | 1 |
| TV Show | 1982 | Yesteryear | Self | 1 |
| TV Show | 2014 | Last Week Tonight with John Oliver | Self | 1 |
| TV Show | 1969 | Sesame Street | Buzz Aldrin | 1 |
| TV Show | N/A | Science Fiction Film Awards | Himself | 1 |
